Exploring Tenebrio molitor as a source of low-molecular-weight antimicrobial peptides using a n in silico approach: correlation of molecular features and molecular docking

[Background] Yellow mealworm (Tenebrio molitor) larvae are increasingly recognized as a potential source of bioactive peptides due to their high protein content. Antimicrobial peptides from sustainable sources are a research topic of interest. This study aims to characterize the peptidome of T. moli...

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Detalles Bibliográficos
Autores: González-de la Rosa, Teresa, Márquez-Paradas, Elvira, Leon, Maria J, Montserrat-de la Paz, Sergio, Rivero-Pino, Fernando
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/390841
Acceso en línea:http://hdl.handle.net/10261/390841
https://api.elsevier.com/content/abstract/scopus_id/85206655293
Access Level:acceso abierto
Palabra clave:Bacteria
Bioactive peptides
Fungi
Peptidome
Proteomic profile
Virus
Descripción
Sumario:[Background] Yellow mealworm (Tenebrio molitor) larvae are increasingly recognized as a potential source of bioactive peptides due to their high protein content. Antimicrobial peptides from sustainable sources are a research topic of interest. This study aims to characterize the peptidome of T. molitor flour and an Alcalase-derived hydrolysate, and to explore the potential presence of antimicrobial peptides using in silico analyses, including prediction tools, molecular docking and parameter correlations.