Unravelling the role of secretory Immnuoglobulin-A in COVID-19: a multicentre study in nursing homes during the first wave

The function of mucosal secretory IgA (SIgA) seems to be paramount in the immune response against SARS-CoV-2 however, there are few studies addressing this issue specifically in the institutionalized older population. This study aims to determine the levels of secretory IgA against the S1 domain of...

ver descrição completa

Detalhes bibliográficos
Autores: Bielza Galindo, Rafael, Pérez, Patricia, García, Nuria, Ballesteros Sanabria, Laura, Martínez, Rosa María, Ghazi, Azam, Hernando, Clara, Rodríguez, María Victoria, Thuissard Vasallo, Israel John, Andreu Vázquez, Cristina, Et al.
Tipo de documento: artigo
Data de publicação:2024
País:España
Recursos:Universidad Europea (UEM)
Repositório:ABACUS. Repositorio de Producción Científica
Idioma:inglês
OAI Identifier:oai:abacus.universidadeuropea.com:11268/13388
Acesso em linha:http://hdl.handle.net/11268/13388
Access Level:Acceso aberto
Palavra-chave:Pandemia
Inmunología
Anciano
Goal 3: Ensure healthy lives and promote well-being for all at all ages
Goal 4: Quality education
Descrição
Resumo:The function of mucosal secretory IgA (SIgA) seems to be paramount in the immune response against SARS-CoV-2 however, there are few studies addressing this issue specifically in the institutionalized older population. This study aims to determine the levels of secretory IgA against the S1 domain of the SARS-CoV-2 spike (SIgA-S1) in older people living in nursing homes (NH) and to investigate the differences in baseline characteristics, severity of COVID-19, duration of symptoms, 30-day mortality, and reinfection according to the levels of SIgA-S1.