Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot study

The purpose of this study was to determine the accuracy of autofluorescence techniques for diagnosing oral mucosa lesions, using as reference pattern for comparison the visual diagnosis made by a clinical specialist. A pilot study was conducted with 60 patients divided in a control group without muc...

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Detalles Bibliográficos
Autores: Jané Salas, Enric, Blanco Carrión, Andrés, Jover Armengol, Lluís de, López López, José, 1958-
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/133453
Acceso en línea:https://hdl.handle.net/2445/133453
Access Level:acceso abierto
Palabra clave:Fluorescència
Diagnòstic
Ferides i lesions
Mucosa oral
Fluorescence
Diagnosis
Wounds and injuries
Oral mucosa
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spelling Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot studyJané Salas, EnricBlanco Carrión, AndrésJover Armengol, Lluís deLópez López, José, 1958-FluorescènciaDiagnòsticFerides i lesionsMucosa oralFluorescenceDiagnosisWounds and injuriesOral mucosaThe purpose of this study was to determine the accuracy of autofluorescence techniques for diagnosing oral mucosa lesions, using as reference pattern for comparison the visual diagnosis made by a clinical specialist. A pilot study was conducted with 60 patients divided in a control group without mucosal pathology and a study group with known clinical history for mucosal pathology. Both groups were examined by an oral medicine specialist and by a general dentist who used VELscope(r) system, which applies tissue fluorescence visualization to identify oral mucosal abnormalities. Using the VELscope(r) system, the general dentist made overdiagnosis in two cases and underdiagnosis in one case. The sensitivity and specificity for the oral medicine specialist were 1 (95% CI: 0.884 to 1). For the general dentist, the sensitivity did not improve significantly with the use of VELscope(r) system [0.53 (95% CI: 0.343 to 0.717) versus 0.49 (95% CI: 0.406 to 0.773)] and the specificity was 0.80 (95% CI: 0.614 to 0.923). A limitation of the study is the small sample size, which does not fully represent a population and extrapolation of the data should be done carefully. Based on the obtained results, no clinical benefits were obtained using this VELscope(r) system.Dental Foundation of Ribeirão Preto2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/133453Articles publicats en revistes (Odontoestomatologia)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1590/0103-6440201300181Brazilian Dental Journal , 2015, vol. 26, num. 6, p. 580-586https://doi.org/10.1590/0103-6440201300181cc-by-nc (c) Jané Salas, Enric et al., 2015http://creativecommons.org/licenses/by-nc/3.0/esinfo:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1334532026-05-27T06:46:51Z
dc.title.none.fl_str_mv Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot study
title Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot study
spellingShingle Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot study
Jané Salas, Enric
Fluorescència
Diagnòstic
Ferides i lesions
Mucosa oral
Fluorescence
Diagnosis
Wounds and injuries
Oral mucosa
title_short Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot study
title_full Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot study
title_fullStr Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot study
title_full_unstemmed Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot study
title_sort Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot study
dc.creator.none.fl_str_mv Jané Salas, Enric
Blanco Carrión, Andrés
Jover Armengol, Lluís de
López López, José, 1958-
author Jané Salas, Enric
author_facet Jané Salas, Enric
Blanco Carrión, Andrés
Jover Armengol, Lluís de
López López, José, 1958-
author_role author
author2 Blanco Carrión, Andrés
Jover Armengol, Lluís de
López López, José, 1958-
author2_role author
author
author
dc.subject.none.fl_str_mv Fluorescència
Diagnòstic
Ferides i lesions
Mucosa oral
Fluorescence
Diagnosis
Wounds and injuries
Oral mucosa
topic Fluorescència
Diagnòstic
Ferides i lesions
Mucosa oral
Fluorescence
Diagnosis
Wounds and injuries
Oral mucosa
description The purpose of this study was to determine the accuracy of autofluorescence techniques for diagnosing oral mucosa lesions, using as reference pattern for comparison the visual diagnosis made by a clinical specialist. A pilot study was conducted with 60 patients divided in a control group without mucosal pathology and a study group with known clinical history for mucosal pathology. Both groups were examined by an oral medicine specialist and by a general dentist who used VELscope(r) system, which applies tissue fluorescence visualization to identify oral mucosal abnormalities. Using the VELscope(r) system, the general dentist made overdiagnosis in two cases and underdiagnosis in one case. The sensitivity and specificity for the oral medicine specialist were 1 (95% CI: 0.884 to 1). For the general dentist, the sensitivity did not improve significantly with the use of VELscope(r) system [0.53 (95% CI: 0.343 to 0.717) versus 0.49 (95% CI: 0.406 to 0.773)] and the specificity was 0.80 (95% CI: 0.614 to 0.923). A limitation of the study is the small sample size, which does not fully represent a population and extrapolation of the data should be done carefully. Based on the obtained results, no clinical benefits were obtained using this VELscope(r) system.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/133453
url https://hdl.handle.net/2445/133453
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1590/0103-6440201300181
Brazilian Dental Journal , 2015, vol. 26, num. 6, p. 580-586
https://doi.org/10.1590/0103-6440201300181
dc.rights.none.fl_str_mv cc-by-nc (c) Jané Salas, Enric et al., 2015
http://creativecommons.org/licenses/by-nc/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by-nc (c) Jané Salas, Enric et al., 2015
http://creativecommons.org/licenses/by-nc/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Dental Foundation of Ribeirão Preto
publisher.none.fl_str_mv Dental Foundation of Ribeirão Preto
dc.source.none.fl_str_mv Articles publicats en revistes (Odontoestomatologia)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869419583708856320
score 15,301603

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