The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies

Despite the significant differences in pathological background of neurodegenerative diseases,epileptic seizures are a comorbidity in many disorders such as Huntington disease (HD), Alzheimer 'sdisease (AD), and multiple sclerosis (MS). Regarding the last one, specifically, it has been shownthat...

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Autores: Rayatpour, Atefeh, Farhangi, Sahar, Verdaguer Cardona, Ester, Olloquequi, Jordi, Ureña Bares, Jesús Mariano, Auladell i Costa, M. Carme, Javan, Mohammad
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/184034
Acceso en línea:https://hdl.handle.net/2445/184034
Access Level:acceso abierto
Palabra clave:Malalties neurodegeneratives
Metabolisme cel·lular
Neurodegenerative Diseases
Cell metabolism
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spelling The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient TherapiesRayatpour, AtefehFarhangi, SaharVerdaguer Cardona, EsterOlloquequi, JordiUreña Bares, Jesús MarianoAuladell i Costa, M. CarmeJavan, MohammadMalalties neurodegenerativesMetabolisme cel·lularNeurodegenerative DiseasesCell metabolismDespite the significant differences in pathological background of neurodegenerative diseases,epileptic seizures are a comorbidity in many disorders such as Huntington disease (HD), Alzheimer 'sdisease (AD), and multiple sclerosis (MS). Regarding the last one, specifically, it has been shownthat the risk of developing epilepsy is three to six times higher in patients with MS compared tothe general population. In this context, understanding the pathological processes underlying thisconnection will allow for the targeting of the common and shared pathological pathways involvedin both conditions, which may provide a new avenue in the management of neurological disorders.This review provides an outlook of what is known so far about the bidirectional association betweenepilepsy and MSMDPI2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/184034Articles publicats en revistes (Bioquímica i Fisiologia)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.3390/ph14101031Pharmaceuticals, 2021, vol. 14, num. 10, p. 1031https://doi.org/10.3390/ph14101031cc-by (c) Rayatpour, Atefeh et al., 2021https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1840342026-05-27T06:46:51Z
dc.title.none.fl_str_mv The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies
title The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies
spellingShingle The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies
Rayatpour, Atefeh
Malalties neurodegeneratives
Metabolisme cel·lular
Neurodegenerative Diseases
Cell metabolism
title_short The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies
title_full The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies
title_fullStr The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies
title_full_unstemmed The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies
title_sort The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies
dc.creator.none.fl_str_mv Rayatpour, Atefeh
Farhangi, Sahar
Verdaguer Cardona, Ester
Olloquequi, Jordi
Ureña Bares, Jesús Mariano
Auladell i Costa, M. Carme
Javan, Mohammad
author Rayatpour, Atefeh
author_facet Rayatpour, Atefeh
Farhangi, Sahar
Verdaguer Cardona, Ester
Olloquequi, Jordi
Ureña Bares, Jesús Mariano
Auladell i Costa, M. Carme
Javan, Mohammad
author_role author
author2 Farhangi, Sahar
Verdaguer Cardona, Ester
Olloquequi, Jordi
Ureña Bares, Jesús Mariano
Auladell i Costa, M. Carme
Javan, Mohammad
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Malalties neurodegeneratives
Metabolisme cel·lular
Neurodegenerative Diseases
Cell metabolism
topic Malalties neurodegeneratives
Metabolisme cel·lular
Neurodegenerative Diseases
Cell metabolism
description Despite the significant differences in pathological background of neurodegenerative diseases,epileptic seizures are a comorbidity in many disorders such as Huntington disease (HD), Alzheimer 'sdisease (AD), and multiple sclerosis (MS). Regarding the last one, specifically, it has been shownthat the risk of developing epilepsy is three to six times higher in patients with MS compared tothe general population. In this context, understanding the pathological processes underlying thisconnection will allow for the targeting of the common and shared pathological pathways involvedin both conditions, which may provide a new avenue in the management of neurological disorders.This review provides an outlook of what is known so far about the bidirectional association betweenepilepsy and MS
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/184034
url https://hdl.handle.net/2445/184034
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/ph14101031
Pharmaceuticals, 2021, vol. 14, num. 10, p. 1031
https://doi.org/10.3390/ph14101031
dc.rights.none.fl_str_mv cc-by (c) Rayatpour, Atefeh et al., 2021
https://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Rayatpour, Atefeh et al., 2021
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Articles publicats en revistes (Bioquímica i Fisiologia)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300724

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