The role of platelet-activating factor antagonists in the prohylasis of postransplant acute tubular necrosis
Renal reperfusion injury can be defined as the renal damage suffered by a kidney because of reestablishment of blood flow prolonged ischemia. Increased permeability for calcium ions, subsequent activation of endogenous phospholipases, and damage mediated by oxygen free radicals are involved in this...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 1996 |
| País: | España |
| Institución: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2445/156959 |
| Acceso en línea: | https://hdl.handle.net/2445/156959 |
| Access Level: | acceso abierto |
| Palabra clave: | Trasplantament renal Necrosi Agregació plaquetària Kidney transplantation Necrosis Blood platelet aggregation |
| Sumario: | Renal reperfusion injury can be defined as the renal damage suffered by a kidney because of reestablishment of blood flow prolonged ischemia. Increased permeability for calcium ions, subsequent activation of endogenous phospholipases, and damage mediated by oxygen free radicals are involved in this reperfusion injury. Inhibition of inflammatory mediators of endothelial origin, such as superoxide radicals and platelet-activating factor (PAF), is a possible way of protecting the injured endothelium following blood reperfusion. |
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