Recommendations for the clinical approach to immune thrombocytopenia: Spanish ITP working group (GEPTI)

Primary immune thrombocytopenia (ITP) is a complex autoimmune disease whose hallmark is a deregulation of cellular and humoral immunity leading to increased destruction and reduced production of platelets. The heterogeneity of presentation and clinical course hampers personalized approaches for diag...

Descripción completa

Detalles Bibliográficos
Autores: Mingot-Castellano, M. Eva, Sánchez González, Blanca, Spanish Immune Thrombocytopenia Group (GEPTI)
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/68331
Acceso en línea:http://hdl.handle.net/10230/68331
http://dx.doi.org/10.3390/jcm12206422
Access Level:acceso abierto
Palabra clave:Fostamatinib
Glucocorticoids
Intravenous immunoglobulins
Primary immune thrombocytopenia
Recommendations
Rituximab
Descripción
Sumario:Primary immune thrombocytopenia (ITP) is a complex autoimmune disease whose hallmark is a deregulation of cellular and humoral immunity leading to increased destruction and reduced production of platelets. The heterogeneity of presentation and clinical course hampers personalized approaches for diagnosis and management. In 2021, the Spanish ITP Group (GEPTI) of the Spanish Society of Hematology and Hemotherapy (SEHH) updated a consensus document that had been launched in 2011. The updated guidelines have been the reference for the diagnosis and management of primary ITP in Spain ever since. Nevertheless, the emergence of new tools and strategies makes it advisable to review them again. For this reason, we have updated the main recommendations appropriately. Our aim is to provide a practical tool to facilitate the integral management of all aspects of primary ITP management.