Cyclooctyne [60]fullerene hexakis adducts: a globular scaffold for copper-free click chemistry

The synthesis of a new highly symmetric hexakis adduct of C60 appended with 12 cyclooctyne moieties has been carried out. This compound has been used for the copper-free strain-promoted cycloaddition reaction to a series of azides with excellent yields.This strategy for the obtention of clicked addu...

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Detalles Bibliográficos
Autores: Ramos, Soriano, Reina, José J., Pérez, Sánchez, Illescas, Beatriz M., Rojo, Javier, Martín, Nazario
Tipo de recurso: artículo
Fecha de publicación:2016
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/23178
Acceso en línea:https://hdl.handle.net/20.500.14352/23178
Access Level:acceso abierto
Palabra clave:547
Química orgánica (Química)
2306 Química Orgánica
Descripción
Sumario:The synthesis of a new highly symmetric hexakis adduct of C60 appended with 12 cyclooctyne moieties has been carried out. This compound has been used for the copper-free strain-promoted cycloaddition reaction to a series of azides with excellent yields.This strategy for the obtention of clicked adducts of [60]fullerene is of special interest for biological applications.