Thermal desorption-ion mobility spectrometry: A rapid sensor for the detection of cannabinoids and discrimination of Cannabis Sativa L. chemotypes

Existing analytical techniques used for the determination of cannabinoids in Cannabis sativa L. (Cannabis) plants mostly rely on chromatography-based methods. As a rapid alternative for the direct analysis of them, thermal desorption (TD)-ion mobility spectrometry (IMS) was used for obtaining spectr...

Descripción completa

Detalles Bibliográficos
Autores: Contreras, María del Mar, Jurado-Campos, Natividad, Sánchez-Carnerero Callado, Carolina, Arroyo-Manzanares, Natalia, Fernández Romero, Luis, Casano, Salvatore, Marco Colás, Santiago, Arce, Lourdes, Ferreiro-Vera, Carlos
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2018
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/187935
Acceso en línea:https://hdl.handle.net/2445/187935
Access Level:acceso abierto
Palabra clave:Cànnabis
Quimiometria
Espectroscòpia de mobilitat d'ions
Cannabis
Chemometrics
Ion mobility spectroscopy
id ES_cacbaebfda9a4efb8324cb0aabfaded7
oai_identifier_str oai:recercat.cat:2445/187935
network_acronym_str ES
network_name_str España
repository_id_str
spelling Thermal desorption-ion mobility spectrometry: A rapid sensor for the detection of cannabinoids and discrimination of Cannabis Sativa L. chemotypesContreras, María del MarJurado-Campos, NatividadSánchez-Carnerero Callado, CarolinaArroyo-Manzanares, NataliaFernández Romero, LuisCasano, SalvatoreMarco Colás, SantiagoArce, LourdesFerreiro-Vera, CarlosCànnabisQuimiometriaEspectroscòpia de mobilitat d'ionsCannabisChemometricsIon mobility spectroscopyExisting analytical techniques used for the determination of cannabinoids in Cannabis sativa L. (Cannabis) plants mostly rely on chromatography-based methods. As a rapid alternative for the direct analysis of them, thermal desorption (TD)-ion mobility spectrometry (IMS) was used for obtaining spectral fingerprints of single cannabinoids from Cannabis plant extracts and from plant residues on hands after their manipulation. The ionization source was 63Ni, with automatic switchable polarity. Although in both ionization modes there were signals in the TD-IMS spectra of the plant extracts and residues that could be assigned to concrete cannabinoids and chemotypes, most of them could not be clearly distinguished. Alternatively, the global spectral data of the plant extracts and residues were pre-processed and then, using principal component analysis (PCA)-linear discriminant analysis (LDA), grouped in function of their chemotype in a more feasible way. Using this approach, the possibility of false positive responses was also studied analyzing other non-Cannabis plants and tobacco, which were clustered in a different group to those of Cannabis. Therefore, TD-IMS, as analytical tool, and PCA-LDA, as a strategy for data reduction and pattern recognition, can be applied for on-site chemotaxonomic discrimination of Cannabis varieties and detection of illegal marijuana since the IMS equipment is portable and the analysis time is highly short.Elsevier B.V.2022202220182022info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion12 p.application/pdfhttps://hdl.handle.net/2445/187935Articles publicats en revistes (Enginyeria Electrònica i Biomèdica)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1016/j.snb.2018.07.031Sensors and Actuators B-Chemical, 2018, vol. 273, p. 1413-1424https://doi.org/10.1016/j.snb.2018.07.031cc-by-nc-nd (c) Elsevier B.V., 2018https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1879352026-05-29T05:05:01Z
dc.title.none.fl_str_mv Thermal desorption-ion mobility spectrometry: A rapid sensor for the detection of cannabinoids and discrimination of Cannabis Sativa L. chemotypes
title Thermal desorption-ion mobility spectrometry: A rapid sensor for the detection of cannabinoids and discrimination of Cannabis Sativa L. chemotypes
spellingShingle Thermal desorption-ion mobility spectrometry: A rapid sensor for the detection of cannabinoids and discrimination of Cannabis Sativa L. chemotypes
Contreras, María del Mar
Cànnabis
Quimiometria
Espectroscòpia de mobilitat d'ions
Cannabis
Chemometrics
Ion mobility spectroscopy
title_short Thermal desorption-ion mobility spectrometry: A rapid sensor for the detection of cannabinoids and discrimination of Cannabis Sativa L. chemotypes
title_full Thermal desorption-ion mobility spectrometry: A rapid sensor for the detection of cannabinoids and discrimination of Cannabis Sativa L. chemotypes
title_fullStr Thermal desorption-ion mobility spectrometry: A rapid sensor for the detection of cannabinoids and discrimination of Cannabis Sativa L. chemotypes
title_full_unstemmed Thermal desorption-ion mobility spectrometry: A rapid sensor for the detection of cannabinoids and discrimination of Cannabis Sativa L. chemotypes
title_sort Thermal desorption-ion mobility spectrometry: A rapid sensor for the detection of cannabinoids and discrimination of Cannabis Sativa L. chemotypes
dc.creator.none.fl_str_mv Contreras, María del Mar
Jurado-Campos, Natividad
Sánchez-Carnerero Callado, Carolina
Arroyo-Manzanares, Natalia
Fernández Romero, Luis
Casano, Salvatore
Marco Colás, Santiago
Arce, Lourdes
Ferreiro-Vera, Carlos
author Contreras, María del Mar
author_facet Contreras, María del Mar
Jurado-Campos, Natividad
Sánchez-Carnerero Callado, Carolina
Arroyo-Manzanares, Natalia
Fernández Romero, Luis
Casano, Salvatore
Marco Colás, Santiago
Arce, Lourdes
Ferreiro-Vera, Carlos
author_role author
author2 Jurado-Campos, Natividad
Sánchez-Carnerero Callado, Carolina
Arroyo-Manzanares, Natalia
Fernández Romero, Luis
Casano, Salvatore
Marco Colás, Santiago
Arce, Lourdes
Ferreiro-Vera, Carlos
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Cànnabis
Quimiometria
Espectroscòpia de mobilitat d'ions
Cannabis
Chemometrics
Ion mobility spectroscopy
topic Cànnabis
Quimiometria
Espectroscòpia de mobilitat d'ions
Cannabis
Chemometrics
Ion mobility spectroscopy
description Existing analytical techniques used for the determination of cannabinoids in Cannabis sativa L. (Cannabis) plants mostly rely on chromatography-based methods. As a rapid alternative for the direct analysis of them, thermal desorption (TD)-ion mobility spectrometry (IMS) was used for obtaining spectral fingerprints of single cannabinoids from Cannabis plant extracts and from plant residues on hands after their manipulation. The ionization source was 63Ni, with automatic switchable polarity. Although in both ionization modes there were signals in the TD-IMS spectra of the plant extracts and residues that could be assigned to concrete cannabinoids and chemotypes, most of them could not be clearly distinguished. Alternatively, the global spectral data of the plant extracts and residues were pre-processed and then, using principal component analysis (PCA)-linear discriminant analysis (LDA), grouped in function of their chemotype in a more feasible way. Using this approach, the possibility of false positive responses was also studied analyzing other non-Cannabis plants and tobacco, which were clustered in a different group to those of Cannabis. Therefore, TD-IMS, as analytical tool, and PCA-LDA, as a strategy for data reduction and pattern recognition, can be applied for on-site chemotaxonomic discrimination of Cannabis varieties and detection of illegal marijuana since the IMS equipment is portable and the analysis time is highly short.
publishDate 2018
dc.date.none.fl_str_mv 2018
2022
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/187935
url https://hdl.handle.net/2445/187935
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1016/j.snb.2018.07.031
Sensors and Actuators B-Chemical, 2018, vol. 273, p. 1413-1424
https://doi.org/10.1016/j.snb.2018.07.031
dc.rights.none.fl_str_mv cc-by-nc-nd (c) Elsevier B.V., 2018
https://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by-nc-nd (c) Elsevier B.V., 2018
https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 12 p.
application/pdf
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Articles publicats en revistes (Enginyeria Electrònica i Biomèdica)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869419510432268288
score 15.812429

Similares en LA Referencia