The effects of tobacco smoking on age of onset of psychosis and psychotic symptoms in a first-episode psychosis population

BACKGROUND AND AIMS: Research suggests that tobacco smokers may develop psychosis at an earlier age than non-smokers, with effects on psychotic symptoms. We aimed to test the difference in age of onset of psychosis between smokers and non-smokers. DESIGN: Self-report data were collected from smokers...

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Autores: Hickling, Lauren M., Ortiz García de la Foz, Víctor, Ayesa Arriola, Rosa, Crespo Facorro, Benedicto|||0000-0001-9709-1276, McGuire, Philip, Pérez Iglesias, Rocío
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universidad de Cantabria (UC)
Repositorio:UCrea Repositorio Abierto de la Universidad de Cantabria
Idioma:inglés
OAI Identifier:oai:repositorio.unican.es:10902/13718
Acceso en línea:http://hdl.handle.net/10902/13718
Access Level:acceso abierto
Palabra clave:Age of Onset
First-Episode Psychosis
Psychopathology
Psychosis
Smoking
Tobacco
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spelling The effects of tobacco smoking on age of onset of psychosis and psychotic symptoms in a first-episode psychosis populationHickling, Lauren M.Ortiz García de la Foz, VíctorAyesa Arriola, RosaCrespo Facorro, Benedicto|||0000-0001-9709-1276McGuire, PhilipPérez Iglesias, RocíoAge of OnsetFirst-Episode PsychosisPsychopathologyPsychosisSmokingTobaccoBACKGROUND AND AIMS: Research suggests that tobacco smokers may develop psychosis at an earlier age than non-smokers, with effects on psychotic symptoms. We aimed to test the difference in age of onset of psychosis between smokers and non-smokers. DESIGN: Self-report data were collected from smokers and non-smokers in a population of first-episode psychosis patients. SETTING: Out-patient first-episode psychosis programme in Santander (Cantabria), Spain. PARTICIPANTS: Three hundred and ninety-seven patients (226 male, 171 female) who agreed to take part between 2001 and 2011. MEASUREMENTS: Age of onset of psychosis, age of smoking initiation, demographics, family history of psychosis and cannabis use were collected by self-report. FINDINGS: Kaplan-Meier analysis showed that smokers had a significantly lower mean age of psychosis onset [smokers = 27.4 (± 8.1) years, non-smokers = 30.5 (± 9.9) years] than non-smokers (?2(1) = 11.72, P = 0.001). The Cox proportional hazard model showed no significant difference in the age of psychosis onset between smokers and non-smokers adjusted for covariates [hazard ratio (HR) = 1.034, 95% confidence interval (CI) = 0.828-1.291]. Age of psychosis onset was predicted significantly by cannabis use (HR = 2.073, 95% CI = 1.633-2.633) and gender (HR = 1.706, 95% CI = 1.363-2.135). CONCLUSIONS: Smokers do not appear to have a significantly earlier age of psychosis onset than non-smokers after taking into account cannabis use and gender.Society for the Study of AddictionUniversidad de Cantabria20172017-03-01journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articlehttp://hdl.handle.net/10902/13718Addiction. 2017 Mar;112(3):526-532reponame:UCrea Repositorio Abierto de la Universidad de Cantabriainstname:Universidad de Cantabria (UC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:repositorio.unican.es:10902/137182026-06-02T12:39:31Z
dc.title.none.fl_str_mv The effects of tobacco smoking on age of onset of psychosis and psychotic symptoms in a first-episode psychosis population
title The effects of tobacco smoking on age of onset of psychosis and psychotic symptoms in a first-episode psychosis population
spellingShingle The effects of tobacco smoking on age of onset of psychosis and psychotic symptoms in a first-episode psychosis population
Hickling, Lauren M.
Age of Onset
First-Episode Psychosis
Psychopathology
Psychosis
Smoking
Tobacco
title_short The effects of tobacco smoking on age of onset of psychosis and psychotic symptoms in a first-episode psychosis population
title_full The effects of tobacco smoking on age of onset of psychosis and psychotic symptoms in a first-episode psychosis population
title_fullStr The effects of tobacco smoking on age of onset of psychosis and psychotic symptoms in a first-episode psychosis population
title_full_unstemmed The effects of tobacco smoking on age of onset of psychosis and psychotic symptoms in a first-episode psychosis population
title_sort The effects of tobacco smoking on age of onset of psychosis and psychotic symptoms in a first-episode psychosis population
dc.creator.none.fl_str_mv Hickling, Lauren M.
Ortiz García de la Foz, Víctor
Ayesa Arriola, Rosa
Crespo Facorro, Benedicto|||0000-0001-9709-1276
McGuire, Philip
Pérez Iglesias, Rocío
author Hickling, Lauren M.
author_facet Hickling, Lauren M.
Ortiz García de la Foz, Víctor
Ayesa Arriola, Rosa
Crespo Facorro, Benedicto|||0000-0001-9709-1276
McGuire, Philip
Pérez Iglesias, Rocío
author_role author
author2 Ortiz García de la Foz, Víctor
Ayesa Arriola, Rosa
Crespo Facorro, Benedicto|||0000-0001-9709-1276
McGuire, Philip
Pérez Iglesias, Rocío
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad de Cantabria
dc.subject.none.fl_str_mv Age of Onset
First-Episode Psychosis
Psychopathology
Psychosis
Smoking
Tobacco
topic Age of Onset
First-Episode Psychosis
Psychopathology
Psychosis
Smoking
Tobacco
description BACKGROUND AND AIMS: Research suggests that tobacco smokers may develop psychosis at an earlier age than non-smokers, with effects on psychotic symptoms. We aimed to test the difference in age of onset of psychosis between smokers and non-smokers. DESIGN: Self-report data were collected from smokers and non-smokers in a population of first-episode psychosis patients. SETTING: Out-patient first-episode psychosis programme in Santander (Cantabria), Spain. PARTICIPANTS: Three hundred and ninety-seven patients (226 male, 171 female) who agreed to take part between 2001 and 2011. MEASUREMENTS: Age of onset of psychosis, age of smoking initiation, demographics, family history of psychosis and cannabis use were collected by self-report. FINDINGS: Kaplan-Meier analysis showed that smokers had a significantly lower mean age of psychosis onset [smokers = 27.4 (± 8.1) years, non-smokers = 30.5 (± 9.9) years] than non-smokers (?2(1) = 11.72, P = 0.001). The Cox proportional hazard model showed no significant difference in the age of psychosis onset between smokers and non-smokers adjusted for covariates [hazard ratio (HR) = 1.034, 95% confidence interval (CI) = 0.828-1.291]. Age of psychosis onset was predicted significantly by cannabis use (HR = 2.073, 95% CI = 1.633-2.633) and gender (HR = 1.706, 95% CI = 1.363-2.135). CONCLUSIONS: Smokers do not appear to have a significantly earlier age of psychosis onset than non-smokers after taking into account cannabis use and gender.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-03-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10902/13718
url http://hdl.handle.net/10902/13718
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Society for the Study of Addiction
publisher.none.fl_str_mv Society for the Study of Addiction
dc.source.none.fl_str_mv Addiction. 2017 Mar;112(3):526-532
reponame:UCrea Repositorio Abierto de la Universidad de Cantabria
instname:Universidad de Cantabria (UC)
instname_str Universidad de Cantabria (UC)
reponame_str UCrea Repositorio Abierto de la Universidad de Cantabria
collection UCrea Repositorio Abierto de la Universidad de Cantabria
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869419478883762176
score 15,300719

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