The Phylum Bryozoa as a Promising Source of Anticancer Drugs

Figuerola, Blanca; Àvila, Conxita. The Phylum Bryozoa as a Promising Source of Anticancer Drugs. Marine Drugs 17(8): 477 (2019). doi: 10.3390/md17080477

Detalles Bibliográficos
Autores: Figuerola, Blanca, Àvila, Conxita
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/207278
Acceso en línea:http://hdl.handle.net/10261/207278
Access Level:acceso abierto
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spelling The Phylum Bryozoa as a Promising Source of Anticancer DrugsFiguerola, BlancaÀvila, ConxitaFiguerola, Blanca; Àvila, Conxita. The Phylum Bryozoa as a Promising Source of Anticancer Drugs. Marine Drugs 17(8): 477 (2019). doi: 10.3390/md17080477Recent advances in sampling and novel techniques in drug synthesis and isolation have promoted the discovery of anticancer agents from marine organisms to combat this major threat to public health worldwide. Bryozoans, which are filter-feeding, aquatic invertebrates often characterized by a calcified skeleton, are an excellent source of pharmacologically interesting compounds including well-known chemical classes such as alkaloids and polyketides. This review covers the literature for secondary metabolites isolated from marine cheilostome and ctenostome bryozoans that have shown potential as cancer drugs. Moreover, we highlight examples such as bryostatins, the most known class of marine-derived compounds from this animal phylum, which are advancing through anticancer clinical trials due to their low toxicity and antineoplastic activity. The bryozoan antitumor compounds discovered until now show a wide range of chemical diversity and biological activities. Therefore, more research focusing on the isolation of secondary metabolites with potential anticancer properties from bryozoans and other overlooked taxa covering wider geographic areas is needed for an efficient bioprospecting of natural products.Peer reviewedFiguerola, Blanca [0000-0003-4731-9337]202020202019info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://hdl.handle.net/10261/207278reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésNoinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2072782026-05-22T06:33:51Z
dc.title.none.fl_str_mv The Phylum Bryozoa as a Promising Source of Anticancer Drugs
title The Phylum Bryozoa as a Promising Source of Anticancer Drugs
spellingShingle The Phylum Bryozoa as a Promising Source of Anticancer Drugs
Figuerola, Blanca
title_short The Phylum Bryozoa as a Promising Source of Anticancer Drugs
title_full The Phylum Bryozoa as a Promising Source of Anticancer Drugs
title_fullStr The Phylum Bryozoa as a Promising Source of Anticancer Drugs
title_full_unstemmed The Phylum Bryozoa as a Promising Source of Anticancer Drugs
title_sort The Phylum Bryozoa as a Promising Source of Anticancer Drugs
dc.creator.none.fl_str_mv Figuerola, Blanca
Àvila, Conxita
author Figuerola, Blanca
author_facet Figuerola, Blanca
Àvila, Conxita
author_role author
author2 Àvila, Conxita
author2_role author
dc.contributor.none.fl_str_mv Figuerola, Blanca [0000-0003-4731-9337]
description Figuerola, Blanca; Àvila, Conxita. The Phylum Bryozoa as a Promising Source of Anticancer Drugs. Marine Drugs 17(8): 477 (2019). doi: 10.3390/md17080477
publishDate 2019
dc.date.none.fl_str_mv 2019
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/207278
url http://hdl.handle.net/10261/207278
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv No
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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