Males and females with first episode psychosis present distinct profiles of social cognition and metacognition

Deficits in social cognition and metacognition impact the course of psychosis. Sex differences in social cognition and metacognition could explain heterogeneity in psychosis. 174 (58 females) patients with first-episode psychosis completed a clinical, neuropsychological, social cognitive, and metaco...

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Detalles Bibliográficos
Autores: Ferrer-Quintero, M, Fernandez, D, Lopez-Carrilero, R, Birules, I, Barajas, A, Lorente-Rovira, E, Luengo, A, Diaz-Cutraro, L, Verdaguer, M, Garcia-Mieres, H, Gutierrez-Zotes, A, Grasa, E, Pousa, E, Huerta-Ramos, E, Pelaez, T, Barrigon, ML, Gomez-Benito, J, Gonzalez-Higueras, F, Ruiz-Delgado, I, Cid, J, Moritz, S, Sevilla-Llewellyn-Jones, J, Ochoa, S
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repositorio:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p11977
Acceso en línea:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=11977
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85139374274&doi=10.1007%2fs00406-022-01438-0&partnerID=40&md5=9c30a4c7a80f6e6fa3ca7be9dfb6d453
Access Level:acceso abierto
Palabra clave:Sex differences
Profiles
Psychosis
Schizophrenia
Social cognition
Metacognition
Descripción
Sumario:Deficits in social cognition and metacognition impact the course of psychosis. Sex differences in social cognition and metacognition could explain heterogeneity in psychosis. 174 (58 females) patients with first-episode psychosis completed a clinical, neuropsychological, social cognitive, and metacognitive assessment. Subsequent latent profile analysis split by sex yielded two clusters common to both sexes (a Homogeneous group, 53% and 79.3%, and an Indecisive group, 18.3% and 8.6% of males and females, respectively), a specific male profile characterized by presenting jumping to conclusions (28.7%) and a specific female profile characterized by cognitive biases (12.1%). Males and females in the homogeneous profile seem to have a more benign course of illness. Males with jumping to conclusions had more clinical symptoms and more neuropsychological deficits. Females with cognitive biases were younger and had lower self-esteem. These results suggest that males and females may benefit from specific targeted treatment and highlights the need to consider sex when planning interventions.

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