Screening great ape museum specimens for DNA viruses
Natural history museum collections harbour a record of wild species from the past centuries, providing a unique opportunity to study animals as well as their infectious agents. Thousands of great ape specimens are kept in these collections, and could become an important resource for studying the evo...
| Autores: | , , , , , , , , , , , , , , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Recursos: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:10230/69493 |
| Acesso em linha: | http://hdl.handle.net/10230/69493 http://dx.doi.org/10.1038/s41598-024-80780-w |
| Access Level: | acceso abierto |
| Palavra-chave: | Great apes Hepatitis B virus Museomics Target-enrichment capture Viruses |
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| dc.title.none.fl_str_mv |
Screening great ape museum specimens for DNA viruses |
| title |
Screening great ape museum specimens for DNA viruses |
| spellingShingle |
Screening great ape museum specimens for DNA viruses Hämmerle, Michelle Great apes Hepatitis B virus Museomics Target-enrichment capture Viruses |
| title_short |
Screening great ape museum specimens for DNA viruses |
| title_full |
Screening great ape museum specimens for DNA viruses |
| title_fullStr |
Screening great ape museum specimens for DNA viruses |
| title_full_unstemmed |
Screening great ape museum specimens for DNA viruses |
| title_sort |
Screening great ape museum specimens for DNA viruses |
| dc.creator.none.fl_str_mv |
Hämmerle, Michelle Guellil, Meriam Trgovec-Greif, Lovro Cheronet, Olivia Sawyer, Susanna Ruiz-Gartzia, Irune Lizano González, Esther, 1974- Rymbekova, Aigerim Gelabert Xirinachs, Pere, 1991- Bernardi, Paolo Han, Sojung Rattei, Thomas Schuenemann, Verena J. Marquès i Bonet, Tomàs, 1975- Guschanski, Katerina Calvignac-Spencer, Sebastien Pinhasi, Ron Kuhlwilm, Martin |
| author |
Hämmerle, Michelle |
| author_facet |
Hämmerle, Michelle Guellil, Meriam Trgovec-Greif, Lovro Cheronet, Olivia Sawyer, Susanna Ruiz-Gartzia, Irune Lizano González, Esther, 1974- Rymbekova, Aigerim Gelabert Xirinachs, Pere, 1991- Bernardi, Paolo Han, Sojung Rattei, Thomas Schuenemann, Verena J. Marquès i Bonet, Tomàs, 1975- Guschanski, Katerina Calvignac-Spencer, Sebastien Pinhasi, Ron Kuhlwilm, Martin |
| author_role |
author |
| author2 |
Guellil, Meriam Trgovec-Greif, Lovro Cheronet, Olivia Sawyer, Susanna Ruiz-Gartzia, Irune Lizano González, Esther, 1974- Rymbekova, Aigerim Gelabert Xirinachs, Pere, 1991- Bernardi, Paolo Han, Sojung Rattei, Thomas Schuenemann, Verena J. Marquès i Bonet, Tomàs, 1975- Guschanski, Katerina Calvignac-Spencer, Sebastien Pinhasi, Ron Kuhlwilm, Martin |
| author2_role |
author author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
Great apes Hepatitis B virus Museomics Target-enrichment capture Viruses |
| topic |
Great apes Hepatitis B virus Museomics Target-enrichment capture Viruses |
| description |
Natural history museum collections harbour a record of wild species from the past centuries, providing a unique opportunity to study animals as well as their infectious agents. Thousands of great ape specimens are kept in these collections, and could become an important resource for studying the evolution of DNA viruses. Their genetic material is likely to be preserved in dry museum specimens, as reported previously for monkeypox virus genomes from historical orangutan specimens. Here, we screened 209 great ape museum specimens for 99 different DNA viruses, using hybridization capture coupled with short-read high-throughput sequencing. We determined the presence of multiple viruses within this dataset from historical specimens and obtained several near-complete viral genomes. In particular, we report high-coverage (> 18-fold) hepatitis B virus genomes from one gorilla and two chimpanzee individuals, which are phylogenetically placed within clades infecting the respective host species. |
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2024 |
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2024 2025 2025 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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http://hdl.handle.net/10230/69493 http://dx.doi.org/10.1038/s41598-024-80780-w |
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http://hdl.handle.net/10230/69493 http://dx.doi.org/10.1038/s41598-024-80780-w |
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Inglés |
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Inglés |
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Sci Rep. 2024 Nov 30;14(1):29806 info:eu-repo/grantAgreement/EC/H2020/955974 info:eu-repo/grantAgreement/EC/H2020/864203 info:eu-repo/grantAgreement/ES/3PE/PID2021-126004NB-100 |
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http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf application/pdf |
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Nature Research |
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Nature Research |
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reponame:Recercat. Dipósit de la Recerca de Catalunya instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
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Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
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Recercat. Dipósit de la Recerca de Catalunya |
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Recercat. Dipósit de la Recerca de Catalunya |
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1869419349632090112 |
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Screening great ape museum specimens for DNA virusesHämmerle, MichelleGuellil, MeriamTrgovec-Greif, LovroCheronet, OliviaSawyer, SusannaRuiz-Gartzia, IruneLizano González, Esther, 1974-Rymbekova, AigerimGelabert Xirinachs, Pere, 1991-Bernardi, PaoloHan, SojungRattei, ThomasSchuenemann, Verena J.Marquès i Bonet, Tomàs, 1975-Guschanski, KaterinaCalvignac-Spencer, SebastienPinhasi, RonKuhlwilm, MartinGreat apesHepatitis B virusMuseomicsTarget-enrichment captureVirusesNatural history museum collections harbour a record of wild species from the past centuries, providing a unique opportunity to study animals as well as their infectious agents. Thousands of great ape specimens are kept in these collections, and could become an important resource for studying the evolution of DNA viruses. Their genetic material is likely to be preserved in dry museum specimens, as reported previously for monkeypox virus genomes from historical orangutan specimens. Here, we screened 209 great ape museum specimens for 99 different DNA viruses, using hybridization capture coupled with short-read high-throughput sequencing. We determined the presence of multiple viruses within this dataset from historical specimens and obtained several near-complete viral genomes. In particular, we report high-coverage (> 18-fold) hepatitis B virus genomes from one gorilla and two chimpanzee individuals, which are phylogenetically placed within clades infecting the respective host species.This project has been funded by the Vienna Science and Technology Fund (WWTF) [https://doi.org/10.47379/VRG20001] and by the Austrian Science Fund (FWF) [https://doi.org/10.55776/TAI729] to M.K. K.G. received support from the Swedish Research Council (VR) through Grant 2020-03398. L. T.-G. was supported by the European Union’s Horizon 2020 research and innovation program, under the Marie Skłodowska-Curie Actions Innovative Training Networks grant agreement no. 955974 (VIROINF). T.M.-B. is supported by funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 864203), Grant PID2021-126004NB-100 funded by MICIU/AEI/ https://doi.org/10.13039/501100011033 and ERDF/EU(MICIIN/FEDER, UE) and Secretaria d’Universitats i Recerca and CERCA Programme del Departament d’Economia i Coneixement de la Generalitat de Catalunya (GRC 2021 SGR 00177). M.G. was supported by the Austrian Science Fund (FWF) [https://doi.org/10.55776/ESP162]. S.H. was supported by the Austrian Science Fund (FWF) [https://doi.org/10.55776/ESP546].Nature Research202520252024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/69493http://dx.doi.org/10.1038/s41598-024-80780-wreponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésSci Rep. 2024 Nov 30;14(1):29806info:eu-repo/grantAgreement/EC/H2020/955974info:eu-repo/grantAgreement/EC/H2020/864203info:eu-repo/grantAgreement/ES/3PE/PID2021-126004NB-100© The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:10230/694932026-05-29T05:05:01Z |
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