'Head-to-side-chain' cyclodepsipeptides of marine origin

Since the late 1980s, a large number of depsipeptides that contain a new topography, referred to as "head-to-side-chain" cyclodepsipeptides, have been isolated and characterized. These peptides present a unique structural arrangement that comprises a macrocyclic region closed through an es...

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Autores: Pelay Gimeno, Marta, Tulla-Puche, Judit, Albericio Palomera, Fernando
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/152523
Acceso en línea:https://hdl.handle.net/2445/152523
Access Level:acceso abierto
Palabra clave:Productes naturals
Medicaments peptídics
Poliquets
Natural products
Peptide drugs
Polychaeta
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spelling 'Head-to-side-chain' cyclodepsipeptides of marine originPelay Gimeno, MartaTulla-Puche, JuditAlbericio Palomera, FernandoProductes naturalsMedicaments peptídicsPoliquetsNatural productsPeptide drugsPolychaetaSince the late 1980s, a large number of depsipeptides that contain a new topography, referred to as "head-to-side-chain" cyclodepsipeptides, have been isolated and characterized. These peptides present a unique structural arrangement that comprises a macrocyclic region closed through an ester bond between the C-terminus and a β-hydroxyl group, and terminated with a polyketide moiety or a more simple branched aliphatic acid. This structural pattern, the presence of unique and complex residues, and relevant bioactivity are the main features shared by all the members of this new class of depsipeptides, which are reviewed herein.MDPI2020202020132020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion25 p.application/pdfhttps://hdl.handle.net/2445/152523Articles publicats en revistes (Química Inorgànica i Orgànica)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.3390/md11051693Marine Drugs, 2013, vol. 11, num. 5, p. 1693-1717https://doi.org/10.3390/md11051693cc-by (c) Pelay Gimeno, Marta et al., 2013http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:recercat.cat:2445/1525232026-05-29T05:05:01Z
dc.title.none.fl_str_mv 'Head-to-side-chain' cyclodepsipeptides of marine origin
title 'Head-to-side-chain' cyclodepsipeptides of marine origin
spellingShingle 'Head-to-side-chain' cyclodepsipeptides of marine origin
Pelay Gimeno, Marta
Productes naturals
Medicaments peptídics
Poliquets
Natural products
Peptide drugs
Polychaeta
title_short 'Head-to-side-chain' cyclodepsipeptides of marine origin
title_full 'Head-to-side-chain' cyclodepsipeptides of marine origin
title_fullStr 'Head-to-side-chain' cyclodepsipeptides of marine origin
title_full_unstemmed 'Head-to-side-chain' cyclodepsipeptides of marine origin
title_sort 'Head-to-side-chain' cyclodepsipeptides of marine origin
dc.creator.none.fl_str_mv Pelay Gimeno, Marta
Tulla-Puche, Judit
Albericio Palomera, Fernando
author Pelay Gimeno, Marta
author_facet Pelay Gimeno, Marta
Tulla-Puche, Judit
Albericio Palomera, Fernando
author_role author
author2 Tulla-Puche, Judit
Albericio Palomera, Fernando
author2_role author
author
dc.subject.none.fl_str_mv Productes naturals
Medicaments peptídics
Poliquets
Natural products
Peptide drugs
Polychaeta
topic Productes naturals
Medicaments peptídics
Poliquets
Natural products
Peptide drugs
Polychaeta
description Since the late 1980s, a large number of depsipeptides that contain a new topography, referred to as "head-to-side-chain" cyclodepsipeptides, have been isolated and characterized. These peptides present a unique structural arrangement that comprises a macrocyclic region closed through an ester bond between the C-terminus and a β-hydroxyl group, and terminated with a polyketide moiety or a more simple branched aliphatic acid. This structural pattern, the presence of unique and complex residues, and relevant bioactivity are the main features shared by all the members of this new class of depsipeptides, which are reviewed herein.
publishDate 2013
dc.date.none.fl_str_mv 2013
2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/152523
url https://hdl.handle.net/2445/152523
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/md11051693
Marine Drugs, 2013, vol. 11, num. 5, p. 1693-1717
https://doi.org/10.3390/md11051693
dc.rights.none.fl_str_mv cc-by (c) Pelay Gimeno, Marta et al., 2013
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Pelay Gimeno, Marta et al., 2013
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 25 p.
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Articles publicats en revistes (Química Inorgànica i Orgànica)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543