Management strategy of non-ST segment elevation acute coronary syndromes in octogenarians: a call for a personalized approach

The rate of octogenarians among patients with non-ST segment elevation acute coronary syndrome (NSTEACS) will continue to increase in the coming years due to population aging. Routine invasive management of NSTEACS has shown long-term benefit in general population but evidence-based recommendations...

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Detalles Bibliográficos
Autores: Martínez Solano, Jorge, Alonso García, Andrés, Álvarez Zaballos, Sara, Martínez Sellés Oliveria Soares, Manuel
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/11486
Acceso en línea:http://hdl.handle.net/11268/11486
Access Level:acceso abierto
Palabra clave:Infarto del miocardio sin elevación del ST
Síndrome coronario agudo
Anciano
Enfermedad cardiovascular
Tratamiento médico
Descripción
Sumario:The rate of octogenarians among patients with non-ST segment elevation acute coronary syndrome (NSTEACS) will continue to increase in the coming years due to population aging. Routine invasive management of NSTEACS has shown long-term benefit in general population but evidence-based recommendations in this subset of patients remain scarce. The decision-making process in elderly patients should take into account several geriatric factors including frailty, comorbidities, dependency, cognitive impairment, malnutrition, and polymedication. Chronological age is a poor marker of the biological situation in octogenarians and heterogeneity is common. Recent studies support an invasive strategy in most octogenarians. However, observational data suggest that significant comorbidities seem to be related to futility of an invasive approach whereas the risk-benefit balance in frail patients might favor revascularization. Further studies are needed to define a tailored approach in each octogenarian with NSTEACS through a better assessment and quantification of frailty, comorbidities and ischemic risk.