Blood-Based Biomarkers to Search for Atrial Fibrillation in High-Risk Asymptomatic Individuals and Cryptogenic Stroke Patients

Atrial fibrillation (AF) increases the risk of ischemic stroke in asymptomatic individuals and may be the underlying cause of many cryptogenic strokes. We aimed to test the usefulness of candidate blood-biomarkers related to AF pathophysiology in two prospective cohorts representative of those popul...

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Detalles Bibliográficos
Autores: Palà, Elena|||0000-0002-1074-990X, Bustamante, Alejandro|||0000-0003-4390-8900, Pagola, Jorge|||0000-0002-0725-1369, Juega, Jesus|||0000-0003-1309-0730, Francisco Pascual, Jaume|||0000-0002-8841-2581, Penalba, Anna, Rodriguez, Maite, De Lera Alfonso, Mercedes|||0000-0002-3954-9071, Arenillas, Juan F.|||0000-0001-7464-6101, Cabezas, Juan Antonio, Pérez-Sánchez, Soledad|||0000-0002-8940-9763, Moniche, Francisco|||0000-0001-8613-2909, de Torres-Chacón, Reyes, González-Alujas, Teresa, Clua Espuny, Jose Luis|||0000-0002-6508-5741, Ballesta-Ors, Juan|||0000-0002-0971-0936, Ribas, Domingo, Acosta Vélez, Juan Gabriel, Pedrote, Alonso, Gonzalez-Loyola, Felipe|||0000-0003-2947-5520, Gentile Lorente, Delicia, Muñoz, Miguel-Angel|||0000-0002-4083-3248, Molina, Carlos A.|||0000-0001-6058-6259, Montaner, Joan|||0000-0003-4845-2279
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:282449
Acceso en línea:https://ddd.uab.cat/record/282449
https://dx.doi.org/urn:doi:10.3389/fcvm.2022.908053
Access Level:acceso abierto
Palabra clave:Atrial fibrillation
Biomarkers
Cryptogenic stroke
Screening
Stroke
Descripción
Sumario:Atrial fibrillation (AF) increases the risk of ischemic stroke in asymptomatic individuals and may be the underlying cause of many cryptogenic strokes. We aimed to test the usefulness of candidate blood-biomarkers related to AF pathophysiology in two prospective cohorts representative of those populations. Two hundred seventy-four subjects aged 65-75 years with hypertension and diabetes from the AFRICAT cohort, and 218 cryptogenic stroke patients aged.