The bio-oscillator: A circuit for cell-culture assays

A system for cell-culture real-time monitoring using an oscillation-based approach is proposed. The system transforms a cell culture under test into a suitable “biological” oscillator, without needing complex circuitry for excitation and measurement. The obtained oscillation parameters are directly...

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Detalles Bibliográficos
Autores: Huertas Sánchez, Gloria, Maldonado-Jacobi, Andrés, Yúfera García, Alberto, Rueda Rueda, Adoración, Huertas Díaz, José Luis
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2015
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/74509
Acceso en línea:https://hdl.handle.net/11441/74509
https://doi.org/10.1109/TCSII.2014.2386233
Access Level:acceso abierto
Palabra clave:Bioimpedance sensors
Microelectrode
Electrical Cell-substrate Impedance Spectroscopy (ECIS)
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spelling The bio-oscillator: A circuit for cell-culture assaysHuertas Sánchez, GloriaMaldonado-Jacobi, AndrésYúfera García, AlbertoRueda Rueda, AdoraciónHuertas Díaz, José LuisBioimpedance sensorsMicroelectrodeElectrical Cell-substrate Impedance Spectroscopy (ECIS)A system for cell-culture real-time monitoring using an oscillation-based approach is proposed. The system transforms a cell culture under test into a suitable “biological” oscillator, without needing complex circuitry for excitation and measurement. The obtained oscillation parameters are directly related to biological test, owed to an empirically extracted cell–electrode electrical model. A discrete prototype is proposed and experimental results with living cell culture are presented, achieving the expected performances.Ministerio de Economía y Competitividad TEC2011-28302, TEC2013-46242-C3-1-PInstitute of Electrical and Electronics EngineersElectrónica y ElectromagnetismoMinisterio de Economía y Competitividad (MINECO). España2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/74509https://doi.org/10.1109/TCSII.2014.2386233reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésIEEE Transactions on Circuits and Systems - II - Express Briefs, 62 (2), 164-168.TEC2011-28302TEC2013-46242-C3-1-Phttp://dx.doi.org/10.1109/TCSII.2014.2386233info:eu-repo/semantics/openAccessoai:idus.us.es:11441/745092026-06-17T12:51:07Z
dc.title.none.fl_str_mv The bio-oscillator: A circuit for cell-culture assays
title The bio-oscillator: A circuit for cell-culture assays
spellingShingle The bio-oscillator: A circuit for cell-culture assays
Huertas Sánchez, Gloria
Bioimpedance sensors
Microelectrode
Electrical Cell-substrate Impedance Spectroscopy (ECIS)
title_short The bio-oscillator: A circuit for cell-culture assays
title_full The bio-oscillator: A circuit for cell-culture assays
title_fullStr The bio-oscillator: A circuit for cell-culture assays
title_full_unstemmed The bio-oscillator: A circuit for cell-culture assays
title_sort The bio-oscillator: A circuit for cell-culture assays
dc.creator.none.fl_str_mv Huertas Sánchez, Gloria
Maldonado-Jacobi, Andrés
Yúfera García, Alberto
Rueda Rueda, Adoración
Huertas Díaz, José Luis
author Huertas Sánchez, Gloria
author_facet Huertas Sánchez, Gloria
Maldonado-Jacobi, Andrés
Yúfera García, Alberto
Rueda Rueda, Adoración
Huertas Díaz, José Luis
author_role author
author2 Maldonado-Jacobi, Andrés
Yúfera García, Alberto
Rueda Rueda, Adoración
Huertas Díaz, José Luis
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Electrónica y Electromagnetismo
Ministerio de Economía y Competitividad (MINECO). España
dc.subject.none.fl_str_mv Bioimpedance sensors
Microelectrode
Electrical Cell-substrate Impedance Spectroscopy (ECIS)
topic Bioimpedance sensors
Microelectrode
Electrical Cell-substrate Impedance Spectroscopy (ECIS)
description A system for cell-culture real-time monitoring using an oscillation-based approach is proposed. The system transforms a cell culture under test into a suitable “biological” oscillator, without needing complex circuitry for excitation and measurement. The obtained oscillation parameters are directly related to biological test, owed to an empirically extracted cell–electrode electrical model. A discrete prototype is proposed and experimental results with living cell culture are presented, achieving the expected performances.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/74509
https://doi.org/10.1109/TCSII.2014.2386233
url https://hdl.handle.net/11441/74509
https://doi.org/10.1109/TCSII.2014.2386233
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv IEEE Transactions on Circuits and Systems - II - Express Briefs, 62 (2), 164-168.
TEC2011-28302
TEC2013-46242-C3-1-P
http://dx.doi.org/10.1109/TCSII.2014.2386233
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Institute of Electrical and Electronics Engineers
publisher.none.fl_str_mv Institute of Electrical and Electronics Engineers
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301629

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