Simple isophthalamides/dipicolineamides as active transmembrane anion transporters

Eight N,N´-diarylisophthalamide/dipicolineamide derivatives have been synthesised and fully characterised, both in solution and in the solid state. The transmembrane anion transport properties of these compounds have been studied by chloride-selective electrode and fluorescence experiments. The subs...

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Detalles Bibliográficos
Autores: Picci, Giacomo, Carreira Barral, Israel, Alonso Carrillo, Daniel, Sanz González, David, Fernández López, Pablo, García Valverde, María, Caltagirone, Claudia, Quesada Pato, Roberto
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Universidad de Burgos (UBU)
Repositorio:Repositorio Institucional de la Universidad de Burgos (RIUBU)
OAI Identifier:oai:riubu.ubu.es:10259/5707
Acceso en línea:http://hdl.handle.net/10259/5707
Access Level:acceso abierto
Palabra clave:Anion binding
anion transport
ion-selective electrode
liposomes
Química orgánica
Chemistry, Organic
Descripción
Sumario:Eight N,N´-diarylisophthalamide/dipicolineamide derivatives have been synthesised and fully characterised, both in solution and in the solid state. The transmembrane anion transport properties of these compounds have been studied by chloride-selective electrode and fluorescence experiments. The substitution pattern of the aromatic moieties determines the transport properties of these systems, with those containing electron-withdrawing groups in their structures being the most active ones of the series.