The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia

Mental disorders affect nearly 970 million people worldwide, impacting individuals and healthcare systems. Large population databases offer insights often unattainable in smaller studies, but their findings may not always generalize across diverse regions. To address this, we introduce a European co...

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Autores: De Prisco, Michele, Oliva, Vincenzo, Fico, Giovanna, Mas, Ariadna, Valenzuela-Pascual, Clàudia, Montejo, Laura, Bort, Marta, Sommerhoff, Constanza, Bortolozzi, Analía, Miquel-Rio, Lluís, Vilella, Elisabet, Forte, Maria Florencia, Fortea, Lydia, Fernández, Tabatha, Giménez-Palomo, Anna, Sague Vilavella, Maria, Madero, Santiago, Llorca Bofí, Vicent, Bioque, Miquel, Grande, Iria, Murru, Andrea, Pacchiarotti, Isabella, Cavero, Myriam, Blanch, Jordi, Viñas-Bardolet, Clara, Aparicio-Nogué, Vicenç, Martínez-Cerdá, Juan Francisco, Parellada, Eduard, Martínez-Arán, Anabel, Radua, Joaquim, Vieta, Eduard, Hidalgo-Mazzei, Diego, Anmella, Gerard
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/420703
Acceso en línea:http://hdl.handle.net/10261/420703
https://api.elsevier.com/content/abstract/scopus_id/105016726056
Access Level:acceso abierto
Palabra clave:Anxiety
Depression
Longitudinal
Mental health
Population-based cohort
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oai_identifier_str oai:digital.csic.es:10261/420703
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia
title The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia
spellingShingle The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia
De Prisco, Michele
Anxiety
Depression
Longitudinal
Mental health
Population-based cohort
title_short The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia
title_full The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia
title_fullStr The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia
title_full_unstemmed The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia
title_sort The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia
dc.creator.none.fl_str_mv De Prisco, Michele
Oliva, Vincenzo
Fico, Giovanna
Mas, Ariadna
Valenzuela-Pascual, Clàudia
Montejo, Laura
Bort, Marta
Sommerhoff, Constanza
Bortolozzi, Analía
Miquel-Rio, Lluís
Vilella, Elisabet
Forte, Maria Florencia
Fortea, Lydia
Fernández, Tabatha
Giménez-Palomo, Anna
Sague Vilavella, Maria
Madero, Santiago
Llorca Bofí, Vicent
Bioque, Miquel
Grande, Iria
Murru, Andrea
Pacchiarotti, Isabella
Cavero, Myriam
Blanch, Jordi
Viñas-Bardolet, Clara
Aparicio-Nogué, Vicenç
Martínez-Cerdá, Juan Francisco
Parellada, Eduard
Martínez-Arán, Anabel
Radua, Joaquim
Vieta, Eduard
Hidalgo-Mazzei, Diego
Anmella, Gerard
author De Prisco, Michele
author_facet De Prisco, Michele
Oliva, Vincenzo
Fico, Giovanna
Mas, Ariadna
Valenzuela-Pascual, Clàudia
Montejo, Laura
Bort, Marta
Sommerhoff, Constanza
Bortolozzi, Analía
Miquel-Rio, Lluís
Vilella, Elisabet
Forte, Maria Florencia
Fortea, Lydia
Fernández, Tabatha
Giménez-Palomo, Anna
Sague Vilavella, Maria
Madero, Santiago
Llorca Bofí, Vicent
Bioque, Miquel
Grande, Iria
Murru, Andrea
Pacchiarotti, Isabella
Cavero, Myriam
Blanch, Jordi
Viñas-Bardolet, Clara
Aparicio-Nogué, Vicenç
Martínez-Cerdá, Juan Francisco
Parellada, Eduard
Martínez-Arán, Anabel
Radua, Joaquim
Vieta, Eduard
Hidalgo-Mazzei, Diego
Anmella, Gerard
author_role author
author2 Oliva, Vincenzo
Fico, Giovanna
Mas, Ariadna
Valenzuela-Pascual, Clàudia
Montejo, Laura
Bort, Marta
Sommerhoff, Constanza
Bortolozzi, Analía
Miquel-Rio, Lluís
Vilella, Elisabet
Forte, Maria Florencia
Fortea, Lydia
Fernández, Tabatha
Giménez-Palomo, Anna
Sague Vilavella, Maria
Madero, Santiago
Llorca Bofí, Vicent
Bioque, Miquel
Grande, Iria
Murru, Andrea
Pacchiarotti, Isabella
Cavero, Myriam
Blanch, Jordi
Viñas-Bardolet, Clara
Aparicio-Nogué, Vicenç
Martínez-Cerdá, Juan Francisco
Parellada, Eduard
Martínez-Arán, Anabel
Radua, Joaquim
Vieta, Eduard
Hidalgo-Mazzei, Diego
Anmella, Gerard
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Fundació Clínic per a la Recerca Biomèdica
Fundación Española de Psiquiatría y Salud Mental
Sociedad Española de Psiquiatría y Salud Mental
Generalitat de Catalunya
European Commission
Ministerio de Sanidad (España)
Ministerio de Ciencia, Innovación y Universidades (España)
Agencia Estatal de Investigación (España)
Instituto de Salud Carlos III
Fundació La Marató de TV3
Centro de Investigación Biomédica en Red Salud Mental (España)
Bortolozzi, Analía [0000-0002-2069-9192]
Anmella, Gerard [0000-0002-6798-4054]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Anxiety
Depression
Longitudinal
Mental health
Population-based cohort
topic Anxiety
Depression
Longitudinal
Mental health
Population-based cohort
description Mental disorders affect nearly 970 million people worldwide, impacting individuals and healthcare systems. Large population databases offer insights often unattainable in smaller studies, but their findings may not always generalize across diverse regions. To address this, we introduce a European cohort from Catalonia, Spain, allowing for comparisons between individuals with mental disorders and the general population.
publishDate 2025
dc.date.none.fl_str_mv 2025
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/420703
https://api.elsevier.com/content/abstract/scopus_id/105016726056
url http://hdl.handle.net/10261/420703
https://api.elsevier.com/content/abstract/scopus_id/105016726056
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI//TED2021-131999BI00
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-141700OB-I00
The underlying dataset has been published as supplementary material of the article in the publisher platform at https://doi.org/10.1192/j.eurpsy.2025.10103
https://doi.org/10.1192/j.eurpsy.2025.10103
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Cambridge University Press
publisher.none.fl_str_mv Cambridge University Press
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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spelling The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in CataloniaDe Prisco, MicheleOliva, VincenzoFico, GiovannaMas, AriadnaValenzuela-Pascual, ClàudiaMontejo, LauraBort, MartaSommerhoff, ConstanzaBortolozzi, AnalíaMiquel-Rio, LluísVilella, ElisabetForte, Maria FlorenciaFortea, LydiaFernández, TabathaGiménez-Palomo, AnnaSague Vilavella, MariaMadero, SantiagoLlorca Bofí, VicentBioque, MiquelGrande, IriaMurru, AndreaPacchiarotti, IsabellaCavero, MyriamBlanch, JordiViñas-Bardolet, ClaraAparicio-Nogué, VicençMartínez-Cerdá, Juan FranciscoParellada, EduardMartínez-Arán, AnabelRadua, JoaquimVieta, EduardHidalgo-Mazzei, DiegoAnmella, GerardAnxietyDepressionLongitudinalMental healthPopulation-based cohortMental disorders affect nearly 970 million people worldwide, impacting individuals and healthcare systems. Large population databases offer insights often unattainable in smaller studies, but their findings may not always generalize across diverse regions. To address this, we introduce a European cohort from Catalonia, Spain, allowing for comparisons between individuals with mental disorders and the general population.The PRESTO project was supported by the Fundació Clínic per a la Recerca Biomèdica through the Pons Bartran 2020 grant (PI046549); the Spanish Foundation for Psychiatry and Mental Health, the Spanish Psychiatric Society, and the Spanish Society of Biological Psychiatry (PI046813); the Agència de Gestió d’Ajuts Universitaris i de Recerca (AGAUR) – PANDÈMIES 2020 grant (2020PANDE00081), Generalitat de Catalunya; the Ministerio de Sanidad through the Pla Director de Salut Mental i Addiccions and the Direcció General de Planificació i Recerca en Salut, Departament de Salut, Generalitat de Catalunya; and by the Ministerio de Ciencia, Innovación y Universidades (MCIN) and the Agencia Estatal de Investigación (AEI, project TED2021-131999BI00, Strategic Projects Oriented to the Ecological Transition and the Digital Transition 2021), with funding from the European Union NextGenerationEU/PRTR. MDP is supported by the Translational Research Programme for Brain Disorders, IDIBAPS. VO is supported by a Rio Hortega 2024 grant (CM24/00143) from the Spanish Ministry of Science, Innovation and Universities financed by the Instituto de Salud Carlos III (ISCIII) and co-financed by the Fondo Social Europeo Plus (FSE+). CVP is supported by a FPU grant for University Teaching Training (FPU23/01555) from the Spanish Ministry of Science, Innovation, and Universities and would like to thank the Ministry for its support. MBo thanks the support of a Marató-TV3 Foundation grant 202230-31. AB thanks the support MCIU/AEI/FEDER, UE grant (PID2022-141700OB-I00, MCIN/AEI/10.13039/501100011033); Spanish Stress Research Network, MCIN/AEI /10.13039/501100011033; and Fundación La Marató-TV3 and Catalan Government (Grant 202207). EVil thanks the support of the Catalan Agency of Research and Universities (2021SGR01065). MFF received the support of “Contratos predoctorales de formación en investigación en salud" (PFIS22) (FI22/00185) from the Instituto de Salud Carlos III (ISCIII) with European funds from the Recovery, Transformation and Resilience Plan, by virtue of the Resolution of the Directorate of the Carlos III Health Institute, O.A., M.P. of December 14, 2022, granting Predoctoral Research Training Contracts in Health (PFIS Contracts). Funded by the European Union Next Generation EU. She has also been granted by M-AES mobility fellowship (MV24/00050). SM has received support from the “Fundacio Clinic de Recerca Biomedica” through the Emili Letang-Josep Font Scholarship program. VLB is supported by a Rio Hortega 2024 grant (CM24/00074) from the Spanish Ministry of Science, financed by the Instituto de Salud Carlos III (ISCIII) and co-financed by the Fondo Social Europeo Plus (FSE+). MBi thanks the support from the Spanish Ministry of Health, Instituto de Salud Carlos III (PI20/01066), Fundació La Marató de TVV3 (202206-30-31), and the Pons-Bartran legacy (FCRB_IPB1_2023). AMA thanks the support of the Spanish Ministry of Science, Innovation and Universities (PI21/00787, PI24/00432), integrated into the Plan Nacional de I+D+I and co-financed by the Instituto de Salud Carlos III -Subdirección General de Evaluación and the Fondo Europeo de Desarrollo Regional (FEDER); the Generalitat de Catalunya and Secretaria d’Universitats i Recerca del Departament d’Economia i Coneixement (2021 SGR 01128), CERCA Programme, Generalitat de Catalunya; La Marató-TV3 Foundation grants 202235 33. JR thanks the support of the Spanish Ministry of Science, Innovation and Universities (CPII19/00009, PI22/00261), integrated into the Plan Nacional de I + D+I and co-financed by the ISCIII-Subdirección General de Evaluación and the Fondo Europeo de Desarrollo Regional (FEDER) and the Instituto de Salud Carlos III; and the Secretaria d’Universitats i Recerca del Departament d’Economia i Coneixement (2021-SGR-01128). EVie thanks the support of the Spanish Ministry of Science, Innovation and Universities (PI21/00787, PI24/00432) integrated into the Plan Nacional de I+D+I and co-financed by the Instituto de Salud Carlos III -Subdirección General de Evaluación and the Fondo Europeo de Desarrollo Regional (FEDER); the Generalitat de Catalunya and Secretaria d’Universitats i Recerca del Departament d’Economia i Coneixement (2021 SGR 01128), CERCA Programme, Generalitat de Catalunya; La Marató-TV3 Foundation grants 202234-30; the European Union Horizon 2020 research and innovation program (H2020-EU.3.1.1. - Understanding health, wellbeing and disease, H2020-EU.3.1.3. Treating and managing disease: Grant 945151, HORIZON.2.1.1 - Health throughout the Life Course: Grant 101057454 and EIT Health (EDIT-B project). DHM gratefully acknowledges the support of the Spanish Ministry of Health, Instituto de Salud Carlos III (PI049759) and the Pons-Bartran Legacy grant 2024 (FCRB_IPB1_2024). GA thanks the support of the Spanish Ministry of Science, Innovation and Universities financed by the Instituto de Salud Carlos III (ISCIII) and co-financed by the European Social Fund+ (ESF+) (JR23/00050, MV22/00058, CM21/00017); the ISCIII (PI24/00584, PI24/01051, PI21/00340, PI21/00169); the Milken Family Foundation (PI046998); the Fundació Clínic per a la Recerca Biomèdica (FCRB) – Pons Bartan 2020 grant (PI04/6549), the Sociedad Española de Psiquiatría y Salud Mental (SEPSM); the Fundació Vila Saborit; the Societat Catalana de Psiquiatria i Salut Mental (SCPiSM); and the Translational Research Programme for Brain Disorders, IDIBAPS. IG has received support from the Spanish Ministry of Science, Innovation and Universities (MCIN) (PI23/00822) integrated into the Plan Nacional de I+D+I and cofinanced by the ISCIII-Subdirección General de Evaluación and European Union (FEDER, FSE, Next Generation EU/Plan de Recuperación Transformación y Resiliencia_PRTR); the Instituto de Salud Carlos III; the CIBER of Mental Health (CIBERSAM); and Generalitat de Catalunya and Secretaria d’Universitats i Recerca del Departament d’Economia i Coneixement (2021 SGR 01128), CERCA Programme/Generalitat de Catalunya as well as the Fundació Clínic per la Recerca Biomèdica (Pons Bartran 2022-FRCB_PB1_2022). SM has received support from the “Fundacio Clinic de Recerca Biomedica” through the Emili Letang-Josep Font Scholarship program.Peer reviewedCambridge University PressFundació Clínic per a la Recerca BiomèdicaFundación Española de Psiquiatría y Salud MentalSociedad Española de Psiquiatría y Salud MentalGeneralitat de CatalunyaEuropean CommissionMinisterio de Sanidad (España)Ministerio de Ciencia, Innovación y Universidades (España)Agencia Estatal de Investigación (España)Instituto de Salud Carlos IIIFundació La Marató de TV3Centro de Investigación Biomédica en Red Salud Mental (España)Bortolozzi, Analía [0000-0002-2069-9192]Anmella, Gerard [0000-0002-6798-4054]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202620262025info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/420703https://api.elsevier.com/content/abstract/scopus_id/105016726056reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI//TED2021-131999BI00info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-141700OB-I00The underlying dataset has been published as supplementary material of the article in the publisher platform at https://doi.org/10.1192/j.eurpsy.2025.10103https://doi.org/10.1192/j.eurpsy.2025.10103Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/4207032026-05-22T06:33:51Z
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