Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease

19 páginas, 3 figuras, 1 tabla.-- El documento en word es la versión post-print.

Detalles Bibliográficos
Autores: Spyridopoulos, Ioakim, Andrés, Vicente
Tipo de recurso: artículo
Fecha de publicación:1998
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/36386
Acceso en línea:http://hdl.handle.net/10261/36386
Access Level:acceso abierto
Palabra clave:Vascular smooth muscle cells
Endothelial cells
Cell cycle
Atherosclerosis
Restenosis
Angiogenesis
CDKs
Cyclins
CDK inhibitors
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spelling Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular diseaseSpyridopoulos, IoakimAndrés, VicenteVascular smooth muscle cellsEndothelial cellsCell cycleAtherosclerosisRestenosisAngiogenesisCDKsCyclinsCDK inhibitors19 páginas, 3 figuras, 1 tabla.-- El documento en word es la versión post-print.At homeostasis, endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) in the arterial wall are fully differentiated and display a very low proliferative index. However, unlike terminally differentiated cells, mature ECs and VSMCs maintain their ability to dedifferentiate and reenter the cell cycle in response to several environmental stimuli. Because of the contribution of EC and VSMC proliferation to the pathogenesis of several diseases, including cancer and cardiovascular disease, considerable effort has been devoted to elucidate the mechanisms that regulate cell cycle progression in these cell types. These regulatory networks and the implications they may have for cardiovascular disease are reviewed here.Work in V. A. laboratory was supported by grants HL57519 and AG15227 from the National Institutes of Health.Peer reviewedFrontiers in Bioscience Publications201120111998info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://hdl.handle.net/10261/36386reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://www.bioscience.org/1998/v3/d/spyridop/list.htminfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/363862026-05-22T06:33:51Z
dc.title.none.fl_str_mv Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease
title Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease
spellingShingle Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease
Spyridopoulos, Ioakim
Vascular smooth muscle cells
Endothelial cells
Cell cycle
Atherosclerosis
Restenosis
Angiogenesis
CDKs
Cyclins
CDK inhibitors
title_short Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease
title_full Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease
title_fullStr Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease
title_full_unstemmed Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease
title_sort Control of vascular smooth muscle and endothelial cell proliferation and its implication in cardiovascular disease
dc.creator.none.fl_str_mv Spyridopoulos, Ioakim
Andrés, Vicente
author Spyridopoulos, Ioakim
author_facet Spyridopoulos, Ioakim
Andrés, Vicente
author_role author
author2 Andrés, Vicente
author2_role author
dc.subject.none.fl_str_mv Vascular smooth muscle cells
Endothelial cells
Cell cycle
Atherosclerosis
Restenosis
Angiogenesis
CDKs
Cyclins
CDK inhibitors
topic Vascular smooth muscle cells
Endothelial cells
Cell cycle
Atherosclerosis
Restenosis
Angiogenesis
CDKs
Cyclins
CDK inhibitors
description 19 páginas, 3 figuras, 1 tabla.-- El documento en word es la versión post-print.
publishDate 1998
dc.date.none.fl_str_mv 1998
2011
2011
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/36386
url http://hdl.handle.net/10261/36386
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://www.bioscience.org/1998/v3/d/spyridop/list.htm
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers in Bioscience Publications
publisher.none.fl_str_mv Frontiers in Bioscience Publications
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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