Methodology for integrating MCNP6 Monte Carlo simulation into PLUNC for prostate brachytherapy planning

[EN] Brachytherapy is a well-established therapeutic technique for treating tumours involving the placement of radioactive encapsulated sources close to or in direct contact with a tumour. Considering this type of treatments, the purpose of this work is to incorporate Monte Carlo (MC) simulation int...

Descripción completa

Detalles Bibliográficos
Autores: Díaz-Comeche, A., Oliver-Gil, Sandra|||0000-0001-8258-3972, Juste-Vidal, Belen-Jeanne|||0000-0003-1978-3765, Miró Herrero, Rafael|||0000-0003-1012-0869, Verdú Martín, Gumersindo Jesús|||0000-0001-5098-080X
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/220076
Acceso en línea:https://riunet.upv.es/handle/10251/220076
Access Level:acceso abierto
Palabra clave:Monte Carlo Simulation
Brachytherapy
MCNP6
Medical Physics
id ES_c6dfd5aba0c698944d29088faad4b558
oai_identifier_str oai:riunet.upv.es:10251/220076
network_acronym_str ES
network_name_str España
repository_id_str
spelling Methodology for integrating MCNP6 Monte Carlo simulation into PLUNC for prostate brachytherapy planningDíaz-Comeche, A.Oliver-Gil, Sandra|||0000-0001-8258-3972Juste-Vidal, Belen-Jeanne|||0000-0003-1978-3765Miró Herrero, Rafael|||0000-0003-1012-0869Verdú Martín, Gumersindo Jesús|||0000-0001-5098-080XMonte Carlo SimulationBrachytherapyMCNP6Medical Physics[EN] Brachytherapy is a well-established therapeutic technique for treating tumours involving the placement of radioactive encapsulated sources close to or in direct contact with a tumour. Considering this type of treatments, the purpose of this work is to incorporate Monte Carlo (MC) simulation into brachytherapy treatment planning. This approach allows for precise estimation of dose distribution in target organs as well as in Organs At Risk (OAR), due to the accuracy of the MC methods in describing dose deposition. To carry out this work, the medical image visualization and dose analysis tools provided by the open-source planner PlanUNC (PLUNC) were utilized. Additionally, a set of programs was developed which automatize the main steps of a treatment planning segmentation, from DICOM images, exporting geometries determining materials and seeds positions, creating an input file for the simulation code (MCNP6.2) and, finally, reading and visualization of the simulation results in the format of the used planning software. With this methodology, results of 3D dose distribution, isodoses curves, Dose-Volume Histograms (DVH), and absorbed dose in OAR were obtained. Thus, the integration of the MC simulation into PLUNC for brachytherapy treatments, has demonstrate its utility for this purpose, showing adaptability to different anatomical geometries and extensibility to various types of treatments.This work has been funded by the project: Desarrollo de una herramienta de mejora del calculo de dosis a pacientes en tratamientos personalizados de braquiterapia (BrachyDose_MC) (PAID-06-22). (01/01/23-31/12/24) . Investigacion competitiva proyectos. UNIVERSIDAD POLITECNICA DE VALENCIA. This study was also partially supported by IRAMED (CIPROM/2022/38) from "Conselleria d'Innovaci, Universitats, Cincia i Societat Digital" funded by "Generalitat Valenciana", under the program PROMETEO 2023.ElsevierInstituto Universitario de Seguridad Industrial, Radiofísica y MedioambientalDepartamento de Física AplicadaDepartamento de Ingeniería Química y NuclearEscuela Técnica Superior de Ingeniería IndustrialGENERALITAT VALENCIANAUNIVERSIDAD POLITECNICA DE VALENCIARepositorio Institucional de la Universitat Politècnica de València Riunet20242024-10-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://riunet.upv.es/handle/10251/220076reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)InglésengGeneralitat Valenciana https://doi.org/10.13039/501100003359 CIPROM%2F2022%2F38 IONIZING RADIATION DOSE REDUCTION IN MEDICAL APPLICATIONSUniversitat Politècnica de València https://doi.org/10.13039/501100004233 PAID-06-22 Desarrollo de una herramienta de mejora del cálculo de dosis a pacientes en tratamientos personalizados de braquiterapia (BrachyDose_MC)open accesshttp://purl.org/coar/access_right/c_abf2Reconocimiento (by)http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/2200762026-06-13T07:49:27Z
dc.title.none.fl_str_mv Methodology for integrating MCNP6 Monte Carlo simulation into PLUNC for prostate brachytherapy planning
title Methodology for integrating MCNP6 Monte Carlo simulation into PLUNC for prostate brachytherapy planning
spellingShingle Methodology for integrating MCNP6 Monte Carlo simulation into PLUNC for prostate brachytherapy planning
Díaz-Comeche, A.
Monte Carlo Simulation
Brachytherapy
MCNP6
Medical Physics
title_short Methodology for integrating MCNP6 Monte Carlo simulation into PLUNC for prostate brachytherapy planning
title_full Methodology for integrating MCNP6 Monte Carlo simulation into PLUNC for prostate brachytherapy planning
title_fullStr Methodology for integrating MCNP6 Monte Carlo simulation into PLUNC for prostate brachytherapy planning
title_full_unstemmed Methodology for integrating MCNP6 Monte Carlo simulation into PLUNC for prostate brachytherapy planning
title_sort Methodology for integrating MCNP6 Monte Carlo simulation into PLUNC for prostate brachytherapy planning
dc.creator.none.fl_str_mv Díaz-Comeche, A.
Oliver-Gil, Sandra|||0000-0001-8258-3972
Juste-Vidal, Belen-Jeanne|||0000-0003-1978-3765
Miró Herrero, Rafael|||0000-0003-1012-0869
Verdú Martín, Gumersindo Jesús|||0000-0001-5098-080X
author Díaz-Comeche, A.
author_facet Díaz-Comeche, A.
Oliver-Gil, Sandra|||0000-0001-8258-3972
Juste-Vidal, Belen-Jeanne|||0000-0003-1978-3765
Miró Herrero, Rafael|||0000-0003-1012-0869
Verdú Martín, Gumersindo Jesús|||0000-0001-5098-080X
author_role author
author2 Oliver-Gil, Sandra|||0000-0001-8258-3972
Juste-Vidal, Belen-Jeanne|||0000-0003-1978-3765
Miró Herrero, Rafael|||0000-0003-1012-0869
Verdú Martín, Gumersindo Jesús|||0000-0001-5098-080X
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Instituto Universitario de Seguridad Industrial, Radiofísica y Medioambiental
Departamento de Física Aplicada
Departamento de Ingeniería Química y Nuclear
Escuela Técnica Superior de Ingeniería Industrial
GENERALITAT VALENCIANA
UNIVERSIDAD POLITECNICA DE VALENCIA
Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv Monte Carlo Simulation
Brachytherapy
MCNP6
Medical Physics
topic Monte Carlo Simulation
Brachytherapy
MCNP6
Medical Physics
description [EN] Brachytherapy is a well-established therapeutic technique for treating tumours involving the placement of radioactive encapsulated sources close to or in direct contact with a tumour. Considering this type of treatments, the purpose of this work is to incorporate Monte Carlo (MC) simulation into brachytherapy treatment planning. This approach allows for precise estimation of dose distribution in target organs as well as in Organs At Risk (OAR), due to the accuracy of the MC methods in describing dose deposition. To carry out this work, the medical image visualization and dose analysis tools provided by the open-source planner PlanUNC (PLUNC) were utilized. Additionally, a set of programs was developed which automatize the main steps of a treatment planning segmentation, from DICOM images, exporting geometries determining materials and seeds positions, creating an input file for the simulation code (MCNP6.2) and, finally, reading and visualization of the simulation results in the format of the used planning software. With this methodology, results of 3D dose distribution, isodoses curves, Dose-Volume Histograms (DVH), and absorbed dose in OAR were obtained. Thus, the integration of the MC simulation into PLUNC for brachytherapy treatments, has demonstrate its utility for this purpose, showing adaptability to different anatomical geometries and extensibility to various types of treatments.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-10-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/220076
url https://riunet.upv.es/handle/10251/220076
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Generalitat Valenciana https://doi.org/10.13039/501100003359 CIPROM%2F2022%2F38 IONIZING RADIATION DOSE REDUCTION IN MEDICAL APPLICATIONS
Universitat Politècnica de València https://doi.org/10.13039/501100004233 PAID-06-22 Desarrollo de una herramienta de mejora del cálculo de dosis a pacientes en tratamientos personalizados de braquiterapia (BrachyDose_MC)
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento (by)
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento (by)
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869419109314199552
score 15,812429

Similares en LA Referencia