Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection

Toxoplasma gondii is an exceptionally successful parasite that infects a very broad host range, including humans, across the globe. The outcome of infection differs remarkably between hosts, ranging from acute death to sterile infection. These differential disease patterns are strongly influenced by...

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Detalhes bibliográficos
Autores: Mukhopadhyay, Debanjan, Arranz Solís, David, Saeij, Jeroen P. J.
Formato: artículo
Fecha de publicación:2020
País:España
Recursos:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/129374
Acesso em linha:https://hdl.handle.net/20.500.14352/129374
Access Level:acceso abierto
Palavra-chave:576.8
Toxoplasma
Immune response
Strain
Virulence factor
Ileitis
Encephalitis
Parasitología (Veterinaria)
Parasitología (Medicina)
Inmunología
3207.12-1 Parasitología Molecular
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repository_id_str
spelling Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma InfectionMukhopadhyay, DebanjanArranz Solís, DavidSaeij, Jeroen P. J.576.8ToxoplasmaImmune responseStrainVirulence factorIleitisEncephalitisParasitología (Veterinaria)Parasitología (Medicina)Inmunología3207.12-1 Parasitología MolecularToxoplasma gondii is an exceptionally successful parasite that infects a very broad host range, including humans, across the globe. The outcome of infection differs remarkably between hosts, ranging from acute death to sterile infection. These differential disease patterns are strongly influenced by both host- and parasite-specific genetic factors. In this review, we discuss how the clinical outcome of toxoplasmosis varies between hosts and the role of different immune genes and parasite virulence factors, with a special emphasis on Toxoplasma-induced ileitis and encephalitis.FrontiersUniversidad Complutense de Madrid20202020-01-0120202020-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/129374reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/1293742026-06-02T12:44:21Z
dc.title.none.fl_str_mv Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection
title Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection
spellingShingle Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection
Mukhopadhyay, Debanjan
576.8
Toxoplasma
Immune response
Strain
Virulence factor
Ileitis
Encephalitis
Parasitología (Veterinaria)
Parasitología (Medicina)
Inmunología
3207.12-1 Parasitología Molecular
title_short Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection
title_full Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection
title_fullStr Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection
title_full_unstemmed Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection
title_sort Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection
dc.creator.none.fl_str_mv Mukhopadhyay, Debanjan
Arranz Solís, David
Saeij, Jeroen P. J.
author Mukhopadhyay, Debanjan
author_facet Mukhopadhyay, Debanjan
Arranz Solís, David
Saeij, Jeroen P. J.
author_role author
author2 Arranz Solís, David
Saeij, Jeroen P. J.
author2_role author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 576.8
Toxoplasma
Immune response
Strain
Virulence factor
Ileitis
Encephalitis
Parasitología (Veterinaria)
Parasitología (Medicina)
Inmunología
3207.12-1 Parasitología Molecular
topic 576.8
Toxoplasma
Immune response
Strain
Virulence factor
Ileitis
Encephalitis
Parasitología (Veterinaria)
Parasitología (Medicina)
Inmunología
3207.12-1 Parasitología Molecular
description Toxoplasma gondii is an exceptionally successful parasite that infects a very broad host range, including humans, across the globe. The outcome of infection differs remarkably between hosts, ranging from acute death to sterile infection. These differential disease patterns are strongly influenced by both host- and parasite-specific genetic factors. In this review, we discuss how the clinical outcome of toxoplasmosis varies between hosts and the role of different immune genes and parasite virulence factors, with a special emphasis on Toxoplasma-induced ileitis and encephalitis.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01
2020
2020-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/129374
url https://hdl.handle.net/20.500.14352/129374
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers
publisher.none.fl_str_mv Frontiers
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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