Diabetes Mellitus and Its Implications in Aortic Stenosis Patients

Aortic stenosis (AS) and diabetes mellitus (DM) are both progressive diseases that if left untreated, result in significant morbidity and mortality. Several studies revealed that the prevalence of DM is substantially higher in patients with AS and, thus, the progression from mild to severe AS is gre...

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Detalles Bibliográficos
Autores: Mouriño Álvarez, Laura, Corbacho Alonso, Nerea, Sastre Oliva, Tamara, Corros Vicente, Cecilia, Solis, Jorge, Tejerina Sánchez, María Teresa, Padial, Luis R., Barderas, Maria G.
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/7049
Acceso en línea:https://hdl.handle.net/20.500.14352/7049
Access Level:acceso abierto
Palabra clave:Diabetes mellitus
Aortic stenosis
Calcification
Risk prediction
Endocrinología
Hematología
3205.02 Endocrinología
3205.04 Hematología
Descripción
Sumario:Aortic stenosis (AS) and diabetes mellitus (DM) are both progressive diseases that if left untreated, result in significant morbidity and mortality. Several studies revealed that the prevalence of DM is substantially higher in patients with AS and, thus, the progression from mild to severe AS is greater in those patients with DM. DM and common comorbidities associated with both diseases, DM and AS, increase patient management complexity and make aortic valve replacement the only effective treatment. For that reason, a better understanding of the pathogenesis underlying both these diseases and the relationships between them is necessary to design more appropriate preventive and therapeutic approaches. In this review, we provided an overview of the main aspects of the relationship between AS and DM, including common comorbidities and risk factors. We also discuss the established treatments/therapies in patients with AS and DM.