Locus coeruleus integrity and neuropsychiatric symptoms in a cohort of early- and late-onset Alzheimer's disease

Early-onset Alzheimer's disease (EOAD) shows a higher burden of neuropsychiatric symptoms than late-onset Alzheimer's disease (LOAD). We aim to determine the differences in the severity of neuropsychiatric symptoms and locus coeruleus (LC) integrity between EOAD and LOAD accounting for dis...

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Bibliographic Details
Authors: Falgàs Martínez, Neus, Peña González, Marta, Val Guardiola, Andrea, Pérez Millan, Agnès, Guillén Soley, Núria, Sarto Alonso, Jordi, Esteller Gauxax, Diana, Bosch Capdevila, Beatriz, Fernández Villullas, Guadalupe, Tort Merino, Adrià, Mayà Casalprim, Gerard, Augé Fradera, Josep Maria, Iranzo, Alex, Balasa, Mircea, Lladó Plarrumaní, Albert, Morales Ruiz, Manuel, Bargalló Alabart, Núria, Muñoz Moreno, Emma, Grinberg, Lea T., Sánchez Valle, Raquel
Format: article
Status:Published version
Publication Date:2024
Country:España
Institution:Universidad de Barcelona
Repository:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/221006
Online Access:https://hdl.handle.net/2445/221006
Access Level:Open access
Keyword:Malaltia d'Alzheimer
Norepinefrina
Hormones
Neurotransmissors
Malalties neurodegeneratives
Alzheimer's disease
Noradrenaline
Neurotransmitters
Neurodegenerative Diseases
Description
Summary:Early-onset Alzheimer's disease (EOAD) shows a higher burden of neuropsychiatric symptoms than late-onset Alzheimer's disease (LOAD). We aim to determine the differences in the severity of neuropsychiatric symptoms and locus coeruleus (LC) integrity between EOAD and LOAD accounting for disease stage