Economics of gastroenteropancreatic neuroendocrine tumors

Despite current interest, enthusiasm and progress in the development of therapies for gastroenteropancreatic (GEP) neuroendocrine tumors (NETs), there are substantial gaps in the published literature regarding cost-of-illness analyses, economic evaluation and budget impact analyses. Compounding the...

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Detalles Bibliográficos
Autores: Grande, Enrique|||0000-0002-0134-4732, Díaz, Ángel, López, Carlos, Munarriz, Javier, Reina, Juan-José, Vera, Ruth|||0000-0003-1524-3147, Bernárdez, Beatriz, Aller, Javier, Capdevila Castillón, Jaume|||0000-0003-0718-8619, García-Carbonero, Rocío|||0000-0002-3342-397X, Jiménez Fonseca, Paula|||0000-0003-4592-3813, Trapero-Bertran, Marta|||0000-0002-9233-1776
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:226372
Acceso en línea:https://ddd.uab.cat/record/226372
https://dx.doi.org/urn:doi:10.1177/2042018819828217
Access Level:acceso abierto
Palabra clave:Budget impact
Cost-of-illness
Costs
Economic burden
Economic evaluation
Gastroenteropancreatic neuroendocrine tumors
Resource utilization
Systematic review
Descripción
Sumario:Despite current interest, enthusiasm and progress in the development of therapies for gastroenteropancreatic (GEP) neuroendocrine tumors (NETs), there are substantial gaps in the published literature regarding cost-of-illness analyses, economic evaluation and budget impact analyses. Compounding the issue is that data on resource utilization and cost-effectiveness of different diagnostic and therapeutic modalities for GEP-NETs are scarce. A systematic review on the economic impact of GEP-NETs was carried out using four databases: EMBASE, PubMed, the National Health Service Economic Evaluation Database and Cochrane review. Fully published articles from January 2000 to May 2017, in English and Spanish, were included. All articles that satisfied the inclusion criteria were included in the systematic review; summary descriptive statistics were used to describe the methodological characteristics. The 14 studies selected included cost-of-illness analyses (n = 4), economic evaluations (n = 7) and budget impact analyses (n = 3). Almost all studies were performed in the United States. Healthcare costs for patients with NETs included medication, outpatient visits, hospitalizations, and check-ups/tests. Reducing adverse events is an area where cost savings could be achieved; however, there was not enough evidence on the cost impact of adverse events. There is a lack of data related to resource utilization in the field of GEP-NETs. Therefore, cost-effectiveness and budget impact studies of existing and emerging treatments are urgently needed to help the decision-making process for patients with NETs.