Replication data for "Subcutaneous administration of an endocrine-mimetic platform allows for prolonged tumor-uptake of a tumor-targeted protein"
The dataset includes the physicochemical and in vivo characterization data supporting the article “Subcutaneous administration of an endocrine-mimetic platform allows for prolonged tumor-uptake of a tumor-targeted protein.” It contains measurements of protein size, polydispersity, zeta potential, mo...
| Autores: | , , , , , , , |
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| Tipo de recurso: | conjunto de datos |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Consorci de Serveis Universitaris de Catalunya (CSUC) |
| Repositorio: | CORA.Repositori de Dades de Recerca |
| OAI Identifier: | oai:dnet:cora.rdr____::e4a8c7b1d7738d8c5ae9d0d2a523857e |
| Acceso en línea: | https://doi.org/10.34810/DATA2656 |
| Access Level: | acceso abierto |
| Palabra clave: | Medicine, Health and Life Sciences Modular protein Drug delivery Slow release Biodistribution Tumor targeting Nanoparticles |
| Sumario: | The dataset includes the physicochemical and in vivo characterization data supporting the article “Subcutaneous administration of an endocrine-mimetic platform allows for prolonged tumor-uptake of a tumor-targeted protein.” It contains measurements of protein size, polydispersity, zeta potential, morphology, and release kinetics of zinc-induced secretory granules (SGs) obtained by DLS, FESEM, and TEM, as well as fluorescence-based biodistribution data in mice after subcutaneous, intramuscular, and intraperitoneal administration. The results demonstrate that subcutaneous administration ensures the most sustained protein release and highest tumor accumulation of the CXCR4-targeted T22-GFP-H6 protein. |
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