Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)

Background/Objectives: Like many other countries, the management of pancreatic cancer in Spain has developed in a fragmented manner. This study analyzes clinical outcomes related to patient volume at different centers after left pancreatectomy (LP). Our goal is to determine whether our practices ali...

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Autores: Aparicio López, Daniel, Ramia, Jose Manuel, Villodre, Celia, Rubio García, Juan J., Hernández, Belén, Busquets, Juli, Secanella Medayo, Luis, Peláez, Núria, Alkorta, Maialen, Ariño Hervás, Itziar de, Achalandabaso, Mar, Toledo Martínez, Enrique, Rotellar Sastre, Fernando, Martí Cruchaga, Pablo, Gómez Bravo, Miguel Ángel, Suárez Artacho, Gonzalo, Garcés Albir, Marina, Sabater, Luis, García Plaza, Gabriel, Alcalá, Francisco J., Asensio Díaz, Enrique, Pacheco Díaz, David, Cugat Andorrà, Esteban, Espín Álvarez, Francisco, Galófre Recasens, María, Sánchez Pérez, Belinda, Santoyo, Julio, Calvo, Jorge, Loinaz, Carmelo, García Domingo, María I., Sánchez Cabús, Santiago, Martín Arnau, Belén, Blanco Fernández, Gerardo, Jaén Torrejimeno, Isabel, Domingo del Pozo, Carlos, Payá Llorente, Carmen, González, Carmen, Etxebarría, Eider, López Andújar, Rafael, Ballester, Cristina, Vico Arias, Ana B., Zambudio Carroll, Natalia, Estévez Fernández, Sergio, Nogueira Sixto, Manuel, Miota, José I., Conde, Belén, Suárez Muñoz, Miguel Ángel, Roldán De la Rua, Jorge, Blanco Rodríguez, Angélica, González Bermúdez, Manuel, González de Chaves Rodríguez, Pilar E., Reyes Correa, Betsabé, López Ben, Santiago, Tió, Berta, Mínguez, Javier, Lasa Unzué, Inmaculada, Miyar, Alberto, Solar García, Lorena, Burdío, Fernando, Ielpo, Benedetto, Carabias, Alberto, Sanz Muñoz, María P., Escartín, Alfredo, Vela, Fulthon, Marqués, Elia, Pérez, Adelino, Palomares, Gloria, Calvo Córdoba, Antonio, Castell, José T., Castro, María José, Manzanares, María Cristina, Artigues, Enrique, Blas, Juan Luis, Díez, Luis, Calero, Alicia, Quiñones, José, Rodríguez, Mario, Alcázar, Cándido, Serradilla Martín, Mario
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/223663
Acceso en línea:https://hdl.handle.net/2445/223663
Access Level:acceso abierto
Palabra clave:Pancreatografia
Cirurgia digestiva
Càncer de pàncrees
Gastrointestinal surgery
Pancreatography
Pancreas cancer
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oai_identifier_str oai:diposit.ub.edu:2445/223663
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)
title Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)
spellingShingle Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)
Aparicio López, Daniel
Pancreatografia
Cirurgia digestiva
Càncer de pàncrees
Gastrointestinal surgery
Pancreatography
Pancreas cancer
title_short Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)
title_full Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)
title_fullStr Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)
title_full_unstemmed Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)
title_sort Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)
dc.creator.none.fl_str_mv Aparicio López, Daniel
Ramia, Jose Manuel
Villodre, Celia
Rubio García, Juan J.
Hernández, Belén
Busquets, Juli
Secanella Medayo, Luis
Peláez, Núria
Alkorta, Maialen
Ariño Hervás, Itziar de
Achalandabaso, Mar
Toledo Martínez, Enrique
Rotellar Sastre, Fernando
Martí Cruchaga, Pablo
Gómez Bravo, Miguel Ángel
Suárez Artacho, Gonzalo
Garcés Albir, Marina
Sabater, Luis
García Plaza, Gabriel
Alcalá, Francisco J.
Asensio Díaz, Enrique
Pacheco Díaz, David
Cugat Andorrà, Esteban
Espín Álvarez, Francisco
Galófre Recasens, María
Sánchez Pérez, Belinda
Santoyo, Julio
Calvo, Jorge
Loinaz, Carmelo
García Domingo, María I.
Sánchez Cabús, Santiago
Martín Arnau, Belén
Blanco Fernández, Gerardo
Jaén Torrejimeno, Isabel
Domingo del Pozo, Carlos
Payá Llorente, Carmen
González, Carmen
Etxebarría, Eider
López Andújar, Rafael
Ballester, Cristina
Vico Arias, Ana B.
Zambudio Carroll, Natalia
Estévez Fernández, Sergio
Nogueira Sixto, Manuel
Miota, José I.
Conde, Belén
Suárez Muñoz, Miguel Ángel
Roldán De la Rua, Jorge
Blanco Rodríguez, Angélica
González Bermúdez, Manuel
González de Chaves Rodríguez, Pilar E.
Reyes Correa, Betsabé
López Ben, Santiago
Tió, Berta
Mínguez, Javier
Lasa Unzué, Inmaculada
Miyar, Alberto
Solar García, Lorena
Burdío, Fernando
Ielpo, Benedetto
Carabias, Alberto
Sanz Muñoz, María P.
Escartín, Alfredo
Vela, Fulthon
Marqués, Elia
Pérez, Adelino
Palomares, Gloria
Calvo Córdoba, Antonio
Castell, José T.
Castro, María José
Manzanares, María Cristina
Artigues, Enrique
Blas, Juan Luis
Díez, Luis
Calero, Alicia
Quiñones, José
Rodríguez, Mario
Alcázar, Cándido
Serradilla Martín, Mario
author Aparicio López, Daniel
author_facet Aparicio López, Daniel
Ramia, Jose Manuel
Villodre, Celia
Rubio García, Juan J.
Hernández, Belén
Busquets, Juli
Secanella Medayo, Luis
Peláez, Núria
Alkorta, Maialen
Ariño Hervás, Itziar de
Achalandabaso, Mar
Toledo Martínez, Enrique
Rotellar Sastre, Fernando
Martí Cruchaga, Pablo
Gómez Bravo, Miguel Ángel
Suárez Artacho, Gonzalo
Garcés Albir, Marina
Sabater, Luis
García Plaza, Gabriel
Alcalá, Francisco J.
Asensio Díaz, Enrique
Pacheco Díaz, David
Cugat Andorrà, Esteban
Espín Álvarez, Francisco
Galófre Recasens, María
Sánchez Pérez, Belinda
Santoyo, Julio
Calvo, Jorge
Loinaz, Carmelo
García Domingo, María I.
Sánchez Cabús, Santiago
Martín Arnau, Belén
Blanco Fernández, Gerardo
Jaén Torrejimeno, Isabel
Domingo del Pozo, Carlos
Payá Llorente, Carmen
González, Carmen
Etxebarría, Eider
López Andújar, Rafael
Ballester, Cristina
Vico Arias, Ana B.
Zambudio Carroll, Natalia
Estévez Fernández, Sergio
Nogueira Sixto, Manuel
Miota, José I.
Conde, Belén
Suárez Muñoz, Miguel Ángel
Roldán De la Rua, Jorge
Blanco Rodríguez, Angélica
González Bermúdez, Manuel
González de Chaves Rodríguez, Pilar E.
Reyes Correa, Betsabé
López Ben, Santiago
Tió, Berta
Mínguez, Javier
Lasa Unzué, Inmaculada
Miyar, Alberto
Solar García, Lorena
Burdío, Fernando
Ielpo, Benedetto
Carabias, Alberto
Sanz Muñoz, María P.
Escartín, Alfredo
Vela, Fulthon
Marqués, Elia
Pérez, Adelino
Palomares, Gloria
Calvo Córdoba, Antonio
Castell, José T.
Castro, María José
Manzanares, María Cristina
Artigues, Enrique
Blas, Juan Luis
Díez, Luis
Calero, Alicia
Quiñones, José
Rodríguez, Mario
Alcázar, Cándido
Serradilla Martín, Mario
author_role author
author2 Ramia, Jose Manuel
Villodre, Celia
Rubio García, Juan J.
Hernández, Belén
Busquets, Juli
Secanella Medayo, Luis
Peláez, Núria
Alkorta, Maialen
Ariño Hervás, Itziar de
Achalandabaso, Mar
Toledo Martínez, Enrique
Rotellar Sastre, Fernando
Martí Cruchaga, Pablo
Gómez Bravo, Miguel Ángel
Suárez Artacho, Gonzalo
Garcés Albir, Marina
Sabater, Luis
García Plaza, Gabriel
Alcalá, Francisco J.
Asensio Díaz, Enrique
Pacheco Díaz, David
Cugat Andorrà, Esteban
Espín Álvarez, Francisco
Galófre Recasens, María
Sánchez Pérez, Belinda
Santoyo, Julio
Calvo, Jorge
Loinaz, Carmelo
García Domingo, María I.
Sánchez Cabús, Santiago
Martín Arnau, Belén
Blanco Fernández, Gerardo
Jaén Torrejimeno, Isabel
Domingo del Pozo, Carlos
Payá Llorente, Carmen
González, Carmen
Etxebarría, Eider
López Andújar, Rafael
Ballester, Cristina
Vico Arias, Ana B.
Zambudio Carroll, Natalia
Estévez Fernández, Sergio
Nogueira Sixto, Manuel
Miota, José I.
Conde, Belén
Suárez Muñoz, Miguel Ángel
Roldán De la Rua, Jorge
Blanco Rodríguez, Angélica
González Bermúdez, Manuel
González de Chaves Rodríguez, Pilar E.
Reyes Correa, Betsabé
López Ben, Santiago
Tió, Berta
Mínguez, Javier
Lasa Unzué, Inmaculada
Miyar, Alberto
Solar García, Lorena
Burdío, Fernando
Ielpo, Benedetto
Carabias, Alberto
Sanz Muñoz, María P.
Escartín, Alfredo
Vela, Fulthon
Marqués, Elia
Pérez, Adelino
Palomares, Gloria
Calvo Córdoba, Antonio
Castell, José T.
Castro, María José
Manzanares, María Cristina
Artigues, Enrique
Blas, Juan Luis
Díez, Luis
Calero, Alicia
Quiñones, José
Rodríguez, Mario
Alcázar, Cándido
Serradilla Martín, Mario
author2_role author
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author
author
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dc.subject.none.fl_str_mv Pancreatografia
Cirurgia digestiva
Càncer de pàncrees
Gastrointestinal surgery
Pancreatography
Pancreas cancer
topic Pancreatografia
Cirurgia digestiva
Càncer de pàncrees
Gastrointestinal surgery
Pancreatography
Pancreas cancer
description Background/Objectives: Like many other countries, the management of pancreatic cancer in Spain has developed in a fragmented manner. This study analyzes clinical outcomes related to patient volume at different centers after left pancreatectomy (LP). Our goal is to determine whether our practices align with the standards established in the literature and assess whether centralization's advantages significantly outweigh its disadvantages. Methods: The SPANDISPAN Project (SPANish DIStal PANcreatectomy) is an observational, prospective, multicenter study focused on LP conducted in Spanish Hepato-Pancreato-Biliary (HPB) Surgery Units from 1 February 2022 to 31 January 2023. HPB units were defined as high volume if they performed more than 10 LPs annually. Results: This study included 313 patients who underwent LP at 42 centers across Spain over the course of a year. A total of 40.3% of the procedures were performed in high-volume centers. Significant differences in preoperative variables were only observed in ASA scores, which were higher in the high-volume group. Intraoperatively, minimally invasive surgical techniques were performed more frequently in high-volume centers. Postoperatively, the administration of somatostatin, major complications, and B and C postoperative pancreatic fistula (POPF) were more frequent in low-volume hospitals. Conclusions: The findings revealed that high-volume centers had a higher rate of minimally invasive surgery, lower intraoperative bleeding, fewer complications, and reduced POPFs compared to low-volume centers. However, it is important to note that low-volume centers still demonstrated acceptable outcomes. Thus, the selective referral of more complex laparoscopic procedures could initiate a gradual centralization of surgical practices.
publishDate 2025
dc.date.none.fl_str_mv 2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/223663
url https://hdl.handle.net/2445/223663
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/jcm14176013
Journal of Clinical Medicine, 2025, vol. 14, num. 17, 6013
https://doi.org/10.3390/jcm14176013
dc.rights.none.fl_str_mv cc-by (c) Aparicio López, Daniel et al., 2025
http://creativecommons.org/licenses/by/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Aparicio López, Daniel et al., 2025
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI AG
publisher.none.fl_str_mv MDPI AG
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869418995395854336
spelling Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)Aparicio López, DanielRamia, Jose ManuelVillodre, CeliaRubio García, Juan J.Hernández, BelénBusquets, JuliSecanella Medayo, LuisPeláez, NúriaAlkorta, MaialenAriño Hervás, Itziar deAchalandabaso, MarToledo Martínez, EnriqueRotellar Sastre, FernandoMartí Cruchaga, PabloGómez Bravo, Miguel ÁngelSuárez Artacho, GonzaloGarcés Albir, MarinaSabater, LuisGarcía Plaza, GabrielAlcalá, Francisco J.Asensio Díaz, EnriquePacheco Díaz, DavidCugat Andorrà, EstebanEspín Álvarez, FranciscoGalófre Recasens, MaríaSánchez Pérez, BelindaSantoyo, JulioCalvo, JorgeLoinaz, CarmeloGarcía Domingo, María I.Sánchez Cabús, SantiagoMartín Arnau, BelénBlanco Fernández, GerardoJaén Torrejimeno, IsabelDomingo del Pozo, CarlosPayá Llorente, CarmenGonzález, CarmenEtxebarría, EiderLópez Andújar, RafaelBallester, CristinaVico Arias, Ana B.Zambudio Carroll, NataliaEstévez Fernández, SergioNogueira Sixto, ManuelMiota, José I.Conde, BelénSuárez Muñoz, Miguel ÁngelRoldán De la Rua, JorgeBlanco Rodríguez, AngélicaGonzález Bermúdez, ManuelGonzález de Chaves Rodríguez, Pilar E.Reyes Correa, BetsabéLópez Ben, SantiagoTió, BertaMínguez, JavierLasa Unzué, InmaculadaMiyar, AlbertoSolar García, LorenaBurdío, FernandoIelpo, BenedettoCarabias, AlbertoSanz Muñoz, María P.Escartín, AlfredoVela, FulthonMarqués, EliaPérez, AdelinoPalomares, GloriaCalvo Córdoba, AntonioCastell, José T.Castro, María JoséManzanares, María CristinaArtigues, EnriqueBlas, Juan LuisDíez, LuisCalero, AliciaQuiñones, JoséRodríguez, MarioAlcázar, CándidoSerradilla Martín, MarioPancreatografiaCirurgia digestivaCàncer de pàncreesGastrointestinal surgeryPancreatographyPancreas cancerBackground/Objectives: Like many other countries, the management of pancreatic cancer in Spain has developed in a fragmented manner. This study analyzes clinical outcomes related to patient volume at different centers after left pancreatectomy (LP). Our goal is to determine whether our practices align with the standards established in the literature and assess whether centralization's advantages significantly outweigh its disadvantages. Methods: The SPANDISPAN Project (SPANish DIStal PANcreatectomy) is an observational, prospective, multicenter study focused on LP conducted in Spanish Hepato-Pancreato-Biliary (HPB) Surgery Units from 1 February 2022 to 31 January 2023. HPB units were defined as high volume if they performed more than 10 LPs annually. Results: This study included 313 patients who underwent LP at 42 centers across Spain over the course of a year. A total of 40.3% of the procedures were performed in high-volume centers. Significant differences in preoperative variables were only observed in ASA scores, which were higher in the high-volume group. Intraoperatively, minimally invasive surgical techniques were performed more frequently in high-volume centers. Postoperatively, the administration of somatostatin, major complications, and B and C postoperative pancreatic fistula (POPF) were more frequent in low-volume hospitals. Conclusions: The findings revealed that high-volume centers had a higher rate of minimally invasive surgery, lower intraoperative bleeding, fewer complications, and reduced POPFs compared to low-volume centers. However, it is important to note that low-volume centers still demonstrated acceptable outcomes. Thus, the selective referral of more complex laparoscopic procedures could initiate a gradual centralization of surgical practices.MDPI AG2025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/223663Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.3390/jcm14176013Journal of Clinical Medicine, 2025, vol. 14, num. 17, 6013https://doi.org/10.3390/jcm14176013cc-by (c) Aparicio López, Daniel et al., 2025http://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/2236632026-05-27T06:46:51Z
score 15,81155