Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler Irrigation

Cylindrospermopsin is an emerging cyanotoxin that can lead to phytotoxicity through different mechanisms. The presence of CYN in irrigation waters is of concern due to potential accumulation in plants, increasing the risk of human exposure by the consumption of vegetables. In this case, it is propos...

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Autores: Duque, Fredy, Prieto Ortega, Ana Isabel, Cascajosa Lira, Antonio, Montenegro, Luis Carlos, Campos, Alexandre, Jos Gallego, Ángeles Mencía, Cameán Fernández, Ana María
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2025
País:España
Recursos:Universidad de Sevilla (US)
Repositório:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/176844
Acesso em linha:https://hdl.handle.net/11441/176844
https://doi.org/10.3390/toxins17060301
Access Level:Acceso aberto
Palavra-chave:Bioaccumulation
Biotransformation
Cyanotoxin
Soil irrigation
Sprinkler irrigation
UHPLC-MS/MS
ICP-OES
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spelling Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler IrrigationDuque, FredyPrieto Ortega, Ana IsabelCascajosa Lira, AntonioMontenegro, Luis CarlosCampos, AlexandreJos Gallego, Ángeles MencíaCameán Fernández, Ana MaríaBioaccumulationBiotransformationCyanotoxinSoil irrigationSprinkler irrigationUHPLC-MS/MSICP-OESCylindrospermopsin is an emerging cyanotoxin that can lead to phytotoxicity through different mechanisms. The presence of CYN in irrigation waters is of concern due to potential accumulation in plants, increasing the risk of human exposure by the consumption of vegetables. In this case, it is proposed to evaluate the effects of CYN on a crop considered staple food in Colombia, such as Solanum tuberosum, group Phureja var Criolla Colombia, known as “yellow potato”. This work evaluates for the first time the effects of CYN in potato plants exposed to this toxin using two different irrigation systems, surface and sprinkler irrigation. The parameters evaluated were CYN bioaccumulation and biotransformation in different parts of the potato plants irrigated with water containing CYN at environmentally relevant concentrations (84.65, 33.80, 3.05 and 3.05 µg/L after first, second, and third to fourth applications, respectively) and changes in nutritional mineral content in tubers. For this purpose, the concentrations of CYN and its potential metabolites in leaves, stem, roots, and tubbers of the plants exposed to the toxin were determined by Ultra-high Performance Liquid Chromatography–MS/MS (UHPLC-MS/MS). Mineral content was determined by Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). CYN bioaccumulation was detected only in aerial parts of plants with sprinkler irrigation. A total of 57 CYN metabolites were found, and the main differences obtained in CYN biotransformation are linked to tissues and exposure conditions. There are significant differences in levels of Ca, K, Mg, Na, P, Cu, Fe, Mn, and Zn in tubers depending on CYN treatment, with higher contents after surface irrigation, and lower content with sprinkler application. These results demonstrate that the exposure conditions are an important factor for the potential presence and effects of CYN in potato plants.Multidisciplinary Digital Publishing Institute (MDPI)Nutrición y Bromatología, Toxicología y Medicina LegalEuropean Union (UE)Ministerio de Ciencia, Innovación y Universidades (MICIU). España2025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/176844https://doi.org/10.3390/toxins17060301reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésToxins, 17 (6), 301.TOXICROP 823860PID2019-104890RB-I00https://doi.org/10.3390/toxins17060301info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1768442026-06-17T12:51:07Z
dc.title.none.fl_str_mv Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler Irrigation
title Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler Irrigation
spellingShingle Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler Irrigation
Duque, Fredy
Bioaccumulation
Biotransformation
Cyanotoxin
Soil irrigation
Sprinkler irrigation
UHPLC-MS/MS
ICP-OES
title_short Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler Irrigation
title_full Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler Irrigation
title_fullStr Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler Irrigation
title_full_unstemmed Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler Irrigation
title_sort Bioaccumulation, Distribution and Biotransformation of Cylindrospermopsin in Potato (Solanum tuberosum) After Exposure by Surface or Sprinkler Irrigation
dc.creator.none.fl_str_mv Duque, Fredy
Prieto Ortega, Ana Isabel
Cascajosa Lira, Antonio
Montenegro, Luis Carlos
Campos, Alexandre
Jos Gallego, Ángeles Mencía
Cameán Fernández, Ana María
author Duque, Fredy
author_facet Duque, Fredy
Prieto Ortega, Ana Isabel
Cascajosa Lira, Antonio
Montenegro, Luis Carlos
Campos, Alexandre
Jos Gallego, Ángeles Mencía
Cameán Fernández, Ana María
author_role author
author2 Prieto Ortega, Ana Isabel
Cascajosa Lira, Antonio
Montenegro, Luis Carlos
Campos, Alexandre
Jos Gallego, Ángeles Mencía
Cameán Fernández, Ana María
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Nutrición y Bromatología, Toxicología y Medicina Legal
European Union (UE)
Ministerio de Ciencia, Innovación y Universidades (MICIU). España
dc.subject.none.fl_str_mv Bioaccumulation
Biotransformation
Cyanotoxin
Soil irrigation
Sprinkler irrigation
UHPLC-MS/MS
ICP-OES
topic Bioaccumulation
Biotransformation
Cyanotoxin
Soil irrigation
Sprinkler irrigation
UHPLC-MS/MS
ICP-OES
description Cylindrospermopsin is an emerging cyanotoxin that can lead to phytotoxicity through different mechanisms. The presence of CYN in irrigation waters is of concern due to potential accumulation in plants, increasing the risk of human exposure by the consumption of vegetables. In this case, it is proposed to evaluate the effects of CYN on a crop considered staple food in Colombia, such as Solanum tuberosum, group Phureja var Criolla Colombia, known as “yellow potato”. This work evaluates for the first time the effects of CYN in potato plants exposed to this toxin using two different irrigation systems, surface and sprinkler irrigation. The parameters evaluated were CYN bioaccumulation and biotransformation in different parts of the potato plants irrigated with water containing CYN at environmentally relevant concentrations (84.65, 33.80, 3.05 and 3.05 µg/L after first, second, and third to fourth applications, respectively) and changes in nutritional mineral content in tubers. For this purpose, the concentrations of CYN and its potential metabolites in leaves, stem, roots, and tubbers of the plants exposed to the toxin were determined by Ultra-high Performance Liquid Chromatography–MS/MS (UHPLC-MS/MS). Mineral content was determined by Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). CYN bioaccumulation was detected only in aerial parts of plants with sprinkler irrigation. A total of 57 CYN metabolites were found, and the main differences obtained in CYN biotransformation are linked to tissues and exposure conditions. There are significant differences in levels of Ca, K, Mg, Na, P, Cu, Fe, Mn, and Zn in tubers depending on CYN treatment, with higher contents after surface irrigation, and lower content with sprinkler application. These results demonstrate that the exposure conditions are an important factor for the potential presence and effects of CYN in potato plants.
publishDate 2025
dc.date.none.fl_str_mv 2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/176844
https://doi.org/10.3390/toxins17060301
url https://hdl.handle.net/11441/176844
https://doi.org/10.3390/toxins17060301
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Toxins, 17 (6), 301.
TOXICROP 823860
PID2019-104890RB-I00
https://doi.org/10.3390/toxins17060301
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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