Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines

Mononuclear gold(I) acyclic diaminocarbenes (ADCs) were prepared by the reaction of 1, 2-cyclohexanediamine with the corresponding isocyanide complexes [AuCl(CNR)] (R = Cy, tBu). The three-component coupling of aldehydes, amines, and alkynes was investigated by using these gold(I) ADC complexes. The...

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Autores: Aliaga-Lavrijsen, M., Pérez Herrera, R., Villacampa, M.D., Gimeno, M.C.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Universidad de Zaragoza
Repositorio:Zaguán. Repositorio Digital de la Universidad de Zaragoza
OAI Identifier:oai:zaguan.unizar.es:74961
Acceso en línea:http://zaguan.unizar.es/record/74961
Access Level:acceso abierto
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spelling Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and IndolizinesAliaga-Lavrijsen, M.Pérez Herrera, R.Villacampa, M.D.Gimeno, M.C.Mononuclear gold(I) acyclic diaminocarbenes (ADCs) were prepared by the reaction of 1, 2-cyclohexanediamine with the corresponding isocyanide complexes [AuCl(CNR)] (R = Cy, tBu). The three-component coupling of aldehydes, amines, and alkynes was investigated by using these gold(I) ADC complexes. The new gold(I) metal complexes are highly efficient catalysts for the synthesis of propargylamines and indolizines in the absence of solvent and in mild conditions. This method affords the corresponding final products with excellent yields in short reaction times. Additionally, chiral gold(I) complexes with ADCs have been prepared and tried in the enantioselective synthesis of propargylamines.2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://zaguan.unizar.es/record/74961reponame:Zaguán. Repositorio Digital de la Universidad de Zaragozainstname:Universidad de ZaragozaInglésinfo:eu-repo/grantAgreement/ES/DGA/E07-17Rinfo:eu-repo/grantAgreement/ES/MINECO/CTQ2016-75816-C2-1-Pinfo:eu-repo/grantAgreement/ES/MINECO/CTQ2017-88091-Pinfo:eu-repo/semantics/openAccessoai:zaguan.unizar.es:749612026-05-29T13:59:51Z
dc.title.none.fl_str_mv Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines
title Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines
spellingShingle Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines
Aliaga-Lavrijsen, M.
title_short Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines
title_full Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines
title_fullStr Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines
title_full_unstemmed Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines
title_sort Efficient Gold(I) Acyclic Diaminocarbenes for the Synthesis of Propargylamines and Indolizines
dc.creator.none.fl_str_mv Aliaga-Lavrijsen, M.
Pérez Herrera, R.
Villacampa, M.D.
Gimeno, M.C.
author Aliaga-Lavrijsen, M.
author_facet Aliaga-Lavrijsen, M.
Pérez Herrera, R.
Villacampa, M.D.
Gimeno, M.C.
author_role author
author2 Pérez Herrera, R.
Villacampa, M.D.
Gimeno, M.C.
author2_role author
author
author
description Mononuclear gold(I) acyclic diaminocarbenes (ADCs) were prepared by the reaction of 1, 2-cyclohexanediamine with the corresponding isocyanide complexes [AuCl(CNR)] (R = Cy, tBu). The three-component coupling of aldehydes, amines, and alkynes was investigated by using these gold(I) ADC complexes. The new gold(I) metal complexes are highly efficient catalysts for the synthesis of propargylamines and indolizines in the absence of solvent and in mild conditions. This method affords the corresponding final products with excellent yields in short reaction times. Additionally, chiral gold(I) complexes with ADCs have been prepared and tried in the enantioselective synthesis of propargylamines.
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://zaguan.unizar.es/record/74961
url http://zaguan.unizar.es/record/74961
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/ES/DGA/E07-17R
info:eu-repo/grantAgreement/ES/MINECO/CTQ2016-75816-C2-1-P
info:eu-repo/grantAgreement/ES/MINECO/CTQ2017-88091-P
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
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dc.source.none.fl_str_mv reponame:Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname:Universidad de Zaragoza
instname_str Universidad de Zaragoza
reponame_str Zaguán. Repositorio Digital de la Universidad de Zaragoza
collection Zaguán. Repositorio Digital de la Universidad de Zaragoza
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