Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter-Feeding Amphibian

Microplastics (MPs) are of increasing global concern for species inhabiting aquatic habitats. However, the mechanisms behind animal responses to MPs still require comprehensive exploration. Amphibians are the most threatened vertebrate group with most species having a complex life cycle, commonly wi...

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Autores: Martin, Colette, Ruthsatz, Katharina, Gómez-Mestre, Iván, Burraco, Pablo
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/403302
Acesso em linha:http://hdl.handle.net/10261/403302
https://api.elsevier.com/content/abstract/scopus_id/105008685638
Access Level:acceso abierto
Palavra-chave:Xenopus laevis
Ageing
Amphibian decline
Glucocorticoids
Plastic pollution
Redox status
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spelling Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter-Feeding AmphibianMartin, ColetteRuthsatz, KatharinaGómez-Mestre, IvánBurraco, PabloXenopus laevisAgeingAmphibian declineGlucocorticoidsPlastic pollutionRedox statusMicroplastics (MPs) are of increasing global concern for species inhabiting aquatic habitats. However, the mechanisms behind animal responses to MPs still require comprehensive exploration. Amphibians are the most threatened vertebrate group with most species having a complex life cycle, commonly with an aquatic larval stage. Here, we investigated whether exposure to an environmentally relevant concentration of MPs affects the growth of filter-feeding larvae of the African clawed frog (Xenopus laevis), and the consequences for their stress physiology (corticosterone [CORT] levels), or health and ageing physiology (oxidative stress and telomere length, the latter in the liver and gut). We conducted a 3 × 2 experiment with three levels of fiber exposure (fibers absent -control-, and MP and cellulose fiber treatments), and two stress levels (CORT absent -control-, and CORT present simulating a stressful condition). We observed a negative impact of MP exposure on larval growth; however, this did not alter the CORT levels, oxidative stress. or telomere length. Our study shows that realistic concentrations of MPs are not enough to induce major alterations on the stress or health and ageing physiology of a filter-feeding amphibian. Whether compensatory growth responses during the post-metamorphic stages could lead to detrimental effects later in life should be explored in amphibians and other organisms with complex life cycles.The German Research Foundation (DFG) project (533973724); a new actor on the stage of global change: A multi-level perspective on the toxicity of microplastics pollution in amphibians) supported C.M. and K.R. Ramón y Cajal Fellowship RYC 2023-044964-I (Spanish Ministry of Science and Innovation) supported P.B.Peer reviewedJohn Wiley & SonsGerman Research FoundationMinisterio de Ciencia e Innovación (España)Agencia Estatal de Investigación (España)Ruthsatz, Katharina [0000-0002-3273-2826]Burraco, Pablo [0000-0002-9007-2643]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202520252025info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/403302https://api.elsevier.com/content/abstract/scopus_id/105008685638reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/RYC2023-044964-IBurraco, Pablo; 2024; Dataset of "Growth but not corticosterone, oxidative stress or telomere length is negatively affected by microplastic exposure in a filter-feeding amphibian" [Dataset]; Figshare; https://doi.org/10.6084/m9.figshare.25958923.v1https://doi.org/10.1002/jez.70005Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/4033022026-05-22T06:33:51Z
dc.title.none.fl_str_mv Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter-Feeding Amphibian
title Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter-Feeding Amphibian
spellingShingle Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter-Feeding Amphibian
Martin, Colette
Xenopus laevis
Ageing
Amphibian decline
Glucocorticoids
Plastic pollution
Redox status
title_short Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter-Feeding Amphibian
title_full Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter-Feeding Amphibian
title_fullStr Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter-Feeding Amphibian
title_full_unstemmed Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter-Feeding Amphibian
title_sort Growth but Not Corticosterone, Oxidative Stress, or Telomere Length Is Negatively Affected by Microplastic Exposure in a Filter-Feeding Amphibian
dc.creator.none.fl_str_mv Martin, Colette
Ruthsatz, Katharina
Gómez-Mestre, Iván
Burraco, Pablo
author Martin, Colette
author_facet Martin, Colette
Ruthsatz, Katharina
Gómez-Mestre, Iván
Burraco, Pablo
author_role author
author2 Ruthsatz, Katharina
Gómez-Mestre, Iván
Burraco, Pablo
author2_role author
author
author
dc.contributor.none.fl_str_mv German Research Foundation
Ministerio de Ciencia e Innovación (España)
Agencia Estatal de Investigación (España)
Ruthsatz, Katharina [0000-0002-3273-2826]
Burraco, Pablo [0000-0002-9007-2643]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Xenopus laevis
Ageing
Amphibian decline
Glucocorticoids
Plastic pollution
Redox status
topic Xenopus laevis
Ageing
Amphibian decline
Glucocorticoids
Plastic pollution
Redox status
description Microplastics (MPs) are of increasing global concern for species inhabiting aquatic habitats. However, the mechanisms behind animal responses to MPs still require comprehensive exploration. Amphibians are the most threatened vertebrate group with most species having a complex life cycle, commonly with an aquatic larval stage. Here, we investigated whether exposure to an environmentally relevant concentration of MPs affects the growth of filter-feeding larvae of the African clawed frog (Xenopus laevis), and the consequences for their stress physiology (corticosterone [CORT] levels), or health and ageing physiology (oxidative stress and telomere length, the latter in the liver and gut). We conducted a 3 × 2 experiment with three levels of fiber exposure (fibers absent -control-, and MP and cellulose fiber treatments), and two stress levels (CORT absent -control-, and CORT present simulating a stressful condition). We observed a negative impact of MP exposure on larval growth; however, this did not alter the CORT levels, oxidative stress. or telomere length. Our study shows that realistic concentrations of MPs are not enough to induce major alterations on the stress or health and ageing physiology of a filter-feeding amphibian. Whether compensatory growth responses during the post-metamorphic stages could lead to detrimental effects later in life should be explored in amphibians and other organisms with complex life cycles.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/403302
https://api.elsevier.com/content/abstract/scopus_id/105008685638
url http://hdl.handle.net/10261/403302
https://api.elsevier.com/content/abstract/scopus_id/105008685638
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/RYC2023-044964-I
Burraco, Pablo; 2024; Dataset of "Growth but not corticosterone, oxidative stress or telomere length is negatively affected by microplastic exposure in a filter-feeding amphibian" [Dataset]; Figshare; https://doi.org/10.6084/m9.figshare.25958923.v1
https://doi.org/10.1002/jez.70005
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv John Wiley & Sons
publisher.none.fl_str_mv John Wiley & Sons
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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