​Integrating when and what information in the left parietal lobule allows language rule generalization

A crucial aspect when learning a language is discovering the rules that govern how words are combined in order to convey meanings. Because rules are characterized by sequential co-occurrences between elements (e.g., “These cupcakes are unbelievable”), tracking the statistical relationships between t...

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Autores: Orpella, Joan, Ripollés, Pablo, Ruzzoli, Manuela, Amengual, Julià L., Callejas, Alicia, Martinez-Alvarez, Anna, Soto-Faraco, Salvador, 1970-, de Diego-Balaguer, Ruth
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/46717
Acceso en línea:http://hdl.handle.net/10230/46717
http://dx.doi.org/10.1371/journal.pbio.3000895
Access Level:acceso abierto
Palabra clave:Language acquisition
Transcranial magnetic stimulation
Functional magnetic resonance imaging
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spelling ​Integrating when and what information in the left parietal lobule allows language rule generalizationOrpella, JoanRipollés, PabloRuzzoli, ManuelaAmengual, Julià L.Callejas, AliciaMartinez-Alvarez, AnnaSoto-Faraco, Salvador, 1970-de Diego-Balaguer, RuthLanguage acquisitionTranscranial magnetic stimulationFunctional magnetic resonance imagingA crucial aspect when learning a language is discovering the rules that govern how words are combined in order to convey meanings. Because rules are characterized by sequential co-occurrences between elements (e.g., “These cupcakes are unbelievable”), tracking the statistical relationships between these elements is fundamental. However, purely bottom-up statistical learning alone cannot fully account for the ability to create abstract rule representations that can be generalized, a paramount requirement of linguistic rules. Here, we provide evidence that, after the statistical relations between words have been extracted, the engagement of goal-directed attention is key to enable rule generalization. Incidental learning performance during a rule-learning task on an artificial language revealed a progressive shift from statistical learning to goal-directed attention. In addition, and consistent with the recruitment of attention, functional MRI (fMRI) analyses of late learning stages showed left parietal activity within a broad bilateral dorsal frontoparietal network. Critically, repetitive transcranial magnetic stimulation (rTMS) on participants’ peak of activation within the left parietal cortex impaired their ability to generalize learned rules to a structurally analogous new language. No stimulation or rTMS on a nonrelevant brain region did not have the same interfering effect on generalization. Performance on an additional attentional task showed that this rTMS on the parietal site hindered participants’ ability to integrate “what” (stimulus identity) and “when” (stimulus timing) information about an expected target. The present findings suggest that learning rules from speech is a two-stage process: following statistical learning, goal-directed attention—involving left parietal regions—integrates “what” and “when” stimulus information to facilitate rapid rule generalization.This work was supported by the European Research Council grant ERC-StG-313841 (TuningLang) and the BFU2017-87109-P Grant from the Spanish Ministerio de Ciencia e Innovación (RdD-B) which is part of Agencia Estatal de Investigación (AEI) (Co-funded by the European Regional Development Fund. ERDF, a way to build Europe), the European Research Council (Proof of Concept, ERC, 727595) (SS-F), the Juan de la Cierva Post-Doctorate Fellowship (JCI-2012-12335, Ministerio de Economia y Competividad) (MR) and CERCA Programme / Generalitat de Catalunya for institutional support. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscriptPublic Library of Science (PLoS)202120212020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/46717http://dx.doi.org/10.1371/journal.pbio.3000895reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésPLoS Biol. 2020 Nov 2;18(11):e3000895info:eu-repo/grantAgreement/ES/2PE/BFU2017-87109-Pinfo:eu-repo/grantAgreement/ES/3PN/JCI2012-12335info:eu-repo/grantAgreement/EC/ERC/313841info:eu-repo/grantAgreement/EC/ERC/727595© 2020 Orpella et al. This is an open access article distributed under the terms of the Creative Commons Attribution License https://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:10230/467172026-05-29T05:05:01Z
dc.title.none.fl_str_mv ​Integrating when and what information in the left parietal lobule allows language rule generalization
title ​Integrating when and what information in the left parietal lobule allows language rule generalization
spellingShingle ​Integrating when and what information in the left parietal lobule allows language rule generalization
Orpella, Joan
Language acquisition
Transcranial magnetic stimulation
Functional magnetic resonance imaging
title_short ​Integrating when and what information in the left parietal lobule allows language rule generalization
title_full ​Integrating when and what information in the left parietal lobule allows language rule generalization
title_fullStr ​Integrating when and what information in the left parietal lobule allows language rule generalization
title_full_unstemmed ​Integrating when and what information in the left parietal lobule allows language rule generalization
title_sort ​Integrating when and what information in the left parietal lobule allows language rule generalization
dc.creator.none.fl_str_mv Orpella, Joan
Ripollés, Pablo
Ruzzoli, Manuela
Amengual, Julià L.
Callejas, Alicia
Martinez-Alvarez, Anna
Soto-Faraco, Salvador, 1970-
de Diego-Balaguer, Ruth
author Orpella, Joan
author_facet Orpella, Joan
Ripollés, Pablo
Ruzzoli, Manuela
Amengual, Julià L.
Callejas, Alicia
Martinez-Alvarez, Anna
Soto-Faraco, Salvador, 1970-
de Diego-Balaguer, Ruth
author_role author
author2 Ripollés, Pablo
Ruzzoli, Manuela
Amengual, Julià L.
Callejas, Alicia
Martinez-Alvarez, Anna
Soto-Faraco, Salvador, 1970-
de Diego-Balaguer, Ruth
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Language acquisition
Transcranial magnetic stimulation
Functional magnetic resonance imaging
topic Language acquisition
Transcranial magnetic stimulation
Functional magnetic resonance imaging
description A crucial aspect when learning a language is discovering the rules that govern how words are combined in order to convey meanings. Because rules are characterized by sequential co-occurrences between elements (e.g., “These cupcakes are unbelievable”), tracking the statistical relationships between these elements is fundamental. However, purely bottom-up statistical learning alone cannot fully account for the ability to create abstract rule representations that can be generalized, a paramount requirement of linguistic rules. Here, we provide evidence that, after the statistical relations between words have been extracted, the engagement of goal-directed attention is key to enable rule generalization. Incidental learning performance during a rule-learning task on an artificial language revealed a progressive shift from statistical learning to goal-directed attention. In addition, and consistent with the recruitment of attention, functional MRI (fMRI) analyses of late learning stages showed left parietal activity within a broad bilateral dorsal frontoparietal network. Critically, repetitive transcranial magnetic stimulation (rTMS) on participants’ peak of activation within the left parietal cortex impaired their ability to generalize learned rules to a structurally analogous new language. No stimulation or rTMS on a nonrelevant brain region did not have the same interfering effect on generalization. Performance on an additional attentional task showed that this rTMS on the parietal site hindered participants’ ability to integrate “what” (stimulus identity) and “when” (stimulus timing) information about an expected target. The present findings suggest that learning rules from speech is a two-stage process: following statistical learning, goal-directed attention—involving left parietal regions—integrates “what” and “when” stimulus information to facilitate rapid rule generalization.
publishDate 2020
dc.date.none.fl_str_mv 2020
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/46717
http://dx.doi.org/10.1371/journal.pbio.3000895
url http://hdl.handle.net/10230/46717
http://dx.doi.org/10.1371/journal.pbio.3000895
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv PLoS Biol. 2020 Nov 2;18(11):e3000895
info:eu-repo/grantAgreement/ES/2PE/BFU2017-87109-P
info:eu-repo/grantAgreement/ES/3PN/JCI2012-12335
info:eu-repo/grantAgreement/EC/ERC/313841
info:eu-repo/grantAgreement/EC/ERC/727595
dc.rights.none.fl_str_mv https://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Public Library of Science (PLoS)
publisher.none.fl_str_mv Public Library of Science (PLoS)
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
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