Enkephalins and Pain Modulation : Mechanisms of Action and Therapeutic Perspectives

Enkephalins, a subclass of endogenous opioid peptides, play a pivotal role in pain modulation. Enkephalins primarily exert their effects through opioid receptors located widely throughout both the central and peripheral nervous systems. This review will explore the mechanisms by which enkephalins pr...

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Detalles Bibliográficos
Autor: García-Domínguez, Mario
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universidad Francisco de Vitoria
Repositorio:DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Idioma:inglés
OAI Identifier:oai:ddfv.ufv.es:10641/7631
Acceso en línea:https://hdl.handle.net/10641/7631
Access Level:acceso abierto
Palabra clave:analgesia
disease
enkephalin
opioid peptide
pain
pathology
Biochemistry
Molecular Biology
Journal Article
Review
Yes
yes
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spelling Enkephalins and Pain Modulation : Mechanisms of Action and Therapeutic PerspectivesGarcía-Domínguez, Marioanalgesiadiseaseenkephalinopioid peptidepainpathologyBiochemistryMolecular BiologyJournal ArticleReviewYesyesEnkephalins, a subclass of endogenous opioid peptides, play a pivotal role in pain modulation. Enkephalins primarily exert their effects through opioid receptors located widely throughout both the central and peripheral nervous systems. This review will explore the mechanisms by which enkephalins produce analgesia, emotional regulation, neuroprotection, and other physiological effects. Furthermore, this review will analyze the involvement of enkephalins in the modulation of different pathologies characterized by severe pain. Understanding the complex role of enkephalins in pain processing provides valuable insight into potential therapeutic strategies for managing pain disorders.Facultad de Educación y Psicología20242024-08-0120242024-08-01review articlehttp://purl.org/coar/resource_type/c_dcae04bcinfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10641/7631reponame:DDFV. Repositorio Institucional de la Universidad Francisco de Vitoriainstname:Universidad Francisco de VitoriaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ddfv.ufv.es:10641/76312026-06-11T12:44:57Z
dc.title.none.fl_str_mv Enkephalins and Pain Modulation : Mechanisms of Action and Therapeutic Perspectives
title Enkephalins and Pain Modulation : Mechanisms of Action and Therapeutic Perspectives
spellingShingle Enkephalins and Pain Modulation : Mechanisms of Action and Therapeutic Perspectives
García-Domínguez, Mario
analgesia
disease
enkephalin
opioid peptide
pain
pathology
Biochemistry
Molecular Biology
Journal Article
Review
Yes
yes
title_short Enkephalins and Pain Modulation : Mechanisms of Action and Therapeutic Perspectives
title_full Enkephalins and Pain Modulation : Mechanisms of Action and Therapeutic Perspectives
title_fullStr Enkephalins and Pain Modulation : Mechanisms of Action and Therapeutic Perspectives
title_full_unstemmed Enkephalins and Pain Modulation : Mechanisms of Action and Therapeutic Perspectives
title_sort Enkephalins and Pain Modulation : Mechanisms of Action and Therapeutic Perspectives
dc.creator.none.fl_str_mv García-Domínguez, Mario
author García-Domínguez, Mario
author_facet García-Domínguez, Mario
author_role author
dc.contributor.none.fl_str_mv Facultad de Educación y Psicología
dc.subject.none.fl_str_mv analgesia
disease
enkephalin
opioid peptide
pain
pathology
Biochemistry
Molecular Biology
Journal Article
Review
Yes
yes
topic analgesia
disease
enkephalin
opioid peptide
pain
pathology
Biochemistry
Molecular Biology
Journal Article
Review
Yes
yes
description Enkephalins, a subclass of endogenous opioid peptides, play a pivotal role in pain modulation. Enkephalins primarily exert their effects through opioid receptors located widely throughout both the central and peripheral nervous systems. This review will explore the mechanisms by which enkephalins produce analgesia, emotional regulation, neuroprotection, and other physiological effects. Furthermore, this review will analyze the involvement of enkephalins in the modulation of different pathologies characterized by severe pain. Understanding the complex role of enkephalins in pain processing provides valuable insight into potential therapeutic strategies for managing pain disorders.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-08-01
2024
2024-08-01
dc.type.none.fl_str_mv review article
http://purl.org/coar/resource_type/c_dcae04bc
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10641/7631
url https://hdl.handle.net/10641/7631
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2

http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2

http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
instname:Universidad Francisco de Vitoria
instname_str Universidad Francisco de Vitoria
reponame_str DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
collection DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
repository.name.fl_str_mv
repository.mail.fl_str_mv
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