Long-term effects on immunological, inflammatory markers, and HIV-1 reservoir after switching to a two-drug versus maintaining a three-drug regimen based on integrase inhibitors

[Objective] To compare the long-term effects on immune parameters, inflammation, and HIV-1 reservoir after switching to a two-drug (2DR) versus maintaining an integrase inhibitor (InSTI)-based three-drug regimen (3DR).

Detalhes bibliográficos
Autores: Saborido-Alconchel, Abraham, Serna-Gallego, Ana, Trujillo-Rodríguez, María, Muñoz-Muela, Esperanza, Álvarez-Ríos, Ana Isabel, Lozano, Carmen, Llaves-Flores, Silvia, Espinosa, Nuria, Roca-Oporto, Cristina, Herrero, Marta, Sotomayor, Cesar, Gutiérrez Valencia, Alicia, López-Cortés, Luis F.
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2024
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/386866
Acesso em linha:http://hdl.handle.net/10261/386866
https://api.elsevier.com/content/abstract/scopus_id/85199464907
Access Level:Acceso aberto
Palavra-chave:Triple therapy
HIV-1 infection
HIV-1 treatment
Antiretroviral therapy
Dual therapy
Inflammation
Long-term
Descrição
Resumo:[Objective] To compare the long-term effects on immune parameters, inflammation, and HIV-1 reservoir after switching to a two-drug (2DR) versus maintaining an integrase inhibitor (InSTI)-based three-drug regimen (3DR).