Menopausal shift on women’s health and microbial niches

Menopause marks a key milestone in women’s aging, triggering hormonal, histological, and microbiome changes. This review explores how hormonal shifts during menopause alter the microbiome’s composition, affecting oral, intestinal, and urogenital communities, potentially leading to disease. The micro...

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Bibliographic Details
Authors: Nieto, Maria R., Jiménez Rus, María, Areal Quecuty, Victoria, Lubián-López, Daniel M., Simon-Soro, Aurea
Format: article
Status:Published version
Publication Date:2025
Country:España
Institution:Universidad de Sevilla (US)
Repository:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/167330
Online Access:https://hdl.handle.net/11441/167330
https://doi.org/10.1038/s44294-024-00050-y
Access Level:Open access
Keyword:Menopause
Microbial niches
hormonal shifts
Description
Summary:Menopause marks a key milestone in women’s aging, triggering hormonal, histological, and microbiome changes. This review explores how hormonal shifts during menopause alter the microbiome’s composition, affecting oral, intestinal, and urogenital communities, potentially leading to disease. The microbial metabolism of sex hormones highlights the bidirectional relationship between hormones and the microbiome. Understanding this interplay is crucial for developing personalized interventions to restore microbial balance and improve women’s health during menopause.