Subcortical regional morphology correlates with fluid and spatial intelligence

Neuroimaging studies have revealed associations between intelligence and brain morphology. However, researchers have focused primarily on the anatomical features of the cerebral cortex, whereas subcortical structures, such as the basal ganglia (BG), have often been neglected despite extensive functi...

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Autores: Burgaleta Díaz, Miguel, MacDonald, Penny A., Martínez Rodríguez, Kenia, Román González, Francisco Javier, Álvarez Linera, Juan, Ramos González, Ana, Karama, Sherif, Colom Marañón, Roberto
Tipo de recurso: artículo
Fecha de publicación:2013
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/746440
Acceso en línea:https://hdl.handle.net/10486/746440
https://dx.doi.org/10.1002/hbm.22305
Access Level:acceso abierto
Palabra clave:fluid intelligence
crystallized intelligence
spatial intelligence
basal ganglia
subcortical shape
Psicología
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spelling Subcortical regional morphology correlates with fluid and spatial intelligenceBurgaleta Díaz, MiguelMacDonald, Penny A.Martínez Rodríguez, KeniaRomán González, Francisco JavierÁlvarez Linera, JuanRamos González, AnaKarama, SherifColom Marañón, Robertofluid intelligencecrystallized intelligencespatial intelligencebasal gangliasubcortical shapePsicologíaNeuroimaging studies have revealed associations between intelligence and brain morphology. However, researchers have focused primarily on the anatomical features of the cerebral cortex, whereas subcortical structures, such as the basal ganglia (BG), have often been neglected despite extensive functional evidence on their relation with higher-order cognition. Here we performed shape analyses to understand how individual differences in BG local morphology account for variability in cognitive performance. Structural MRI was acquired in 104 young adults (45 men, 59 women, mean age 5 19.83, SD 5 1.64), and the outer surface of striatal structures (caudate, nucleus accumbens, and putamen), globus pallidus, and thalamus was estimated for each subject and hemisphere. Further, nine cognitive tests were used to measure fluid (Gf), crystallized (Gc), and spatial intelligence (Gv). Latent scores for these factors were computed by means of confirmatory factor analysis and regressed vertex-wise against subcortical shape (local displacements of vertex position), controlling for age, sex, and adjusted for brain size. Significant results (FDR < 5%) were found for Gf and Gv, but not Gc, for the right striatal structures and thalamus. The main results show a relative enlargement of the rostral putamen, which is functionally connected to the right dorsolateral prefrontal cortex and other intelligence-related prefrontal areasMinisterio de Ciencia e Innovación (Ministry of Science and Innovation). Grant Numbers: SEJ2066–07890, PSI2010–20364, SEJ2009–09072, Consolider-Ingenio2010-CDS-2007-00012, FPU AP2006-00934, AP2008-00433, BES-2011–043527, CEMU-2012-004. Universidad Autonoma de Madrid, Alianza 4 Universidades Program. Grant Number: A4U-4–2011WileyDepartamento de Psicología Biológica y de la SaludFacultad de PsicologíaGobierno de España20132013-08-02research articlehttp://purl.org/coar/resource_type/c_2df8fbb1AMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10486/746440https://dx.doi.org/10.1002/hbm.2230523913782reponame:Biblos-e Archivo. Repositorio Institucional de la UAMinstname:Universidad Autónoma de MadridInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:repositorio.uam.es:10486/7464402026-06-23T12:46:27Z
dc.title.none.fl_str_mv Subcortical regional morphology correlates with fluid and spatial intelligence
title Subcortical regional morphology correlates with fluid and spatial intelligence
spellingShingle Subcortical regional morphology correlates with fluid and spatial intelligence
Burgaleta Díaz, Miguel
fluid intelligence
crystallized intelligence
spatial intelligence
basal ganglia
subcortical shape
Psicología
title_short Subcortical regional morphology correlates with fluid and spatial intelligence
title_full Subcortical regional morphology correlates with fluid and spatial intelligence
title_fullStr Subcortical regional morphology correlates with fluid and spatial intelligence
title_full_unstemmed Subcortical regional morphology correlates with fluid and spatial intelligence
title_sort Subcortical regional morphology correlates with fluid and spatial intelligence
dc.creator.none.fl_str_mv Burgaleta Díaz, Miguel
MacDonald, Penny A.
Martínez Rodríguez, Kenia
Román González, Francisco Javier
Álvarez Linera, Juan
Ramos González, Ana
Karama, Sherif
Colom Marañón, Roberto
author Burgaleta Díaz, Miguel
author_facet Burgaleta Díaz, Miguel
MacDonald, Penny A.
Martínez Rodríguez, Kenia
Román González, Francisco Javier
Álvarez Linera, Juan
Ramos González, Ana
Karama, Sherif
Colom Marañón, Roberto
author_role author
author2 MacDonald, Penny A.
Martínez Rodríguez, Kenia
Román González, Francisco Javier
Álvarez Linera, Juan
Ramos González, Ana
Karama, Sherif
Colom Marañón, Roberto
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Departamento de Psicología Biológica y de la Salud
Facultad de Psicología
Gobierno de España
dc.subject.none.fl_str_mv fluid intelligence
crystallized intelligence
spatial intelligence
basal ganglia
subcortical shape
Psicología
topic fluid intelligence
crystallized intelligence
spatial intelligence
basal ganglia
subcortical shape
Psicología
description Neuroimaging studies have revealed associations between intelligence and brain morphology. However, researchers have focused primarily on the anatomical features of the cerebral cortex, whereas subcortical structures, such as the basal ganglia (BG), have often been neglected despite extensive functional evidence on their relation with higher-order cognition. Here we performed shape analyses to understand how individual differences in BG local morphology account for variability in cognitive performance. Structural MRI was acquired in 104 young adults (45 men, 59 women, mean age 5 19.83, SD 5 1.64), and the outer surface of striatal structures (caudate, nucleus accumbens, and putamen), globus pallidus, and thalamus was estimated for each subject and hemisphere. Further, nine cognitive tests were used to measure fluid (Gf), crystallized (Gc), and spatial intelligence (Gv). Latent scores for these factors were computed by means of confirmatory factor analysis and regressed vertex-wise against subcortical shape (local displacements of vertex position), controlling for age, sex, and adjusted for brain size. Significant results (FDR < 5%) were found for Gf and Gv, but not Gc, for the right striatal structures and thalamus. The main results show a relative enlargement of the rostral putamen, which is functionally connected to the right dorsolateral prefrontal cortex and other intelligence-related prefrontal areas
publishDate 2013
dc.date.none.fl_str_mv 2013
2013-08-02
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
AM
http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10486/746440
https://dx.doi.org/10.1002/hbm.22305
23913782
url https://hdl.handle.net/10486/746440
https://dx.doi.org/10.1002/hbm.22305
identifier_str_mv 23913782
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Biblos-e Archivo. Repositorio Institucional de la UAM
instname:Universidad Autónoma de Madrid
instname_str Universidad Autónoma de Madrid
reponame_str Biblos-e Archivo. Repositorio Institucional de la UAM
collection Biblos-e Archivo. Repositorio Institucional de la UAM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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