Chiral Capillary Electrophoresis

The implications of chirality in different environments are already well known and reported extensively in the literature. Capillary Electrophoresis, a separation technique that only requires few nanoliters of sample, has demonstrated its potential for chiral analysis in the past years. The aim of t...

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Autores: Bernardo Bermejo, Samuel|||0000-0001-9126-7453, Sánchez López, Elena, Castro Puyana, María|||0000-0003-1412-4103, Marina Alegre, María Luisa|||0000-0002-5583-1624
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:ebuah.uah.es:10017/48148
Acceso en línea:http://hdl.handle.net/10017/48148
https://dx.doi.org/10.1016/j.trac.2020.115807
Access Level:acceso abierto
Palabra clave:Chiral capillary electrophoresis
Enantiomers
Electrokinetic chromatography
Pharmaceutical formulations
Food
Biological samples
Química
Chemistry
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spelling Chiral Capillary ElectrophoresisBernardo Bermejo, Samuel|||0000-0001-9126-7453Sánchez López, ElenaCastro Puyana, María|||0000-0003-1412-4103Marina Alegre, María Luisa|||0000-0002-5583-1624Chiral capillary electrophoresisEnantiomersElectrokinetic chromatographyPharmaceutical formulationsFoodBiological samplesQuímicaChemistryThe implications of chirality in different environments are already well known and reported extensively in the literature. Capillary Electrophoresis, a separation technique that only requires few nanoliters of sample, has demonstrated its potential for chiral analysis in the past years. The aim of this article is to provide an overview on the fundamentals and characteristics of Chiral Capillary Electrophoresis as well as the main advances and trends in this topic. Special attention is paid to the most recent technological and methodological developments achieved mainly in the most employed separation mode (Electroki-netic Chromatography). The most noteworthy and recent applications reported on the enantiomeric separation and determination of compounds in pharmaceutical, food, biomedical, environmental or forensic samples will also be critically overviewed. The characteristics of the developed methodologies will be detailed in Tables and future trends will also be discussed. (C) 2020 Elsevier B.V. All rights reserved.Comunidad de MadridMinisterio de Economía y Competitividad20202020-03-0120202020-03-0120222022-04-01journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10017/48148https://dx.doi.org/10.1016/j.trac.2020.115807reponame:e_Buah Biblioteca Digital Universidad de Alcaláinstname:Universidad de Alcalá (UAH)InglésengComunidad de Madrid http://dx.doi.org/10.13039/100012818 Not available S2018%2FBAA-4393 ESTRATEGIAS INTEGRADAS PARA LA MEJORA DE LA CALIDAD, LA SEGURIDAD Y LA FUNCIONALIDAD DE LOS ALIMENTOS: HACIA UNA ALIMENTACIÓN SALUDABLEMinisterio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 Not available CTQ2016-76368-P NUEVOS NANOADITIVOS PARA SEPARACIÓN QUIRAL POR ELECTROFORESIS CAPILAR: APLICACIÓN A LA DETERMINACIÓN DE BIOMARCADORESopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-ShareAlike 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccessoai:ebuah.uah.es:10017/481482026-06-18T11:13:07Z
dc.title.none.fl_str_mv Chiral Capillary Electrophoresis
title Chiral Capillary Electrophoresis
spellingShingle Chiral Capillary Electrophoresis
Bernardo Bermejo, Samuel|||0000-0001-9126-7453
Chiral capillary electrophoresis
Enantiomers
Electrokinetic chromatography
Pharmaceutical formulations
Food
Biological samples
Química
Chemistry
title_short Chiral Capillary Electrophoresis
title_full Chiral Capillary Electrophoresis
title_fullStr Chiral Capillary Electrophoresis
title_full_unstemmed Chiral Capillary Electrophoresis
title_sort Chiral Capillary Electrophoresis
dc.creator.none.fl_str_mv Bernardo Bermejo, Samuel|||0000-0001-9126-7453
Sánchez López, Elena
Castro Puyana, María|||0000-0003-1412-4103
Marina Alegre, María Luisa|||0000-0002-5583-1624
author Bernardo Bermejo, Samuel|||0000-0001-9126-7453
author_facet Bernardo Bermejo, Samuel|||0000-0001-9126-7453
Sánchez López, Elena
Castro Puyana, María|||0000-0003-1412-4103
Marina Alegre, María Luisa|||0000-0002-5583-1624
author_role author
author2 Sánchez López, Elena
Castro Puyana, María|||0000-0003-1412-4103
Marina Alegre, María Luisa|||0000-0002-5583-1624
author2_role author
author
author
dc.subject.none.fl_str_mv Chiral capillary electrophoresis
Enantiomers
Electrokinetic chromatography
Pharmaceutical formulations
Food
Biological samples
Química
Chemistry
topic Chiral capillary electrophoresis
Enantiomers
Electrokinetic chromatography
Pharmaceutical formulations
Food
Biological samples
Química
Chemistry
description The implications of chirality in different environments are already well known and reported extensively in the literature. Capillary Electrophoresis, a separation technique that only requires few nanoliters of sample, has demonstrated its potential for chiral analysis in the past years. The aim of this article is to provide an overview on the fundamentals and characteristics of Chiral Capillary Electrophoresis as well as the main advances and trends in this topic. Special attention is paid to the most recent technological and methodological developments achieved mainly in the most employed separation mode (Electroki-netic Chromatography). The most noteworthy and recent applications reported on the enantiomeric separation and determination of compounds in pharmaceutical, food, biomedical, environmental or forensic samples will also be critically overviewed. The characteristics of the developed methodologies will be detailed in Tables and future trends will also be discussed. (C) 2020 Elsevier B.V. All rights reserved.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-03-01
2020
2020-03-01
2022
2022-04-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10017/48148
https://dx.doi.org/10.1016/j.trac.2020.115807
url http://hdl.handle.net/10017/48148
https://dx.doi.org/10.1016/j.trac.2020.115807
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Comunidad de Madrid http://dx.doi.org/10.13039/100012818 Not available S2018%2FBAA-4393 ESTRATEGIAS INTEGRADAS PARA LA MEJORA DE LA CALIDAD, LA SEGURIDAD Y LA FUNCIONALIDAD DE LOS ALIMENTOS: HACIA UNA ALIMENTACIÓN SALUDABLE
Ministerio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 Not available CTQ2016-76368-P NUEVOS NANOADITIVOS PARA SEPARACIÓN QUIRAL POR ELECTROFORESIS CAPILAR: APLICACIÓN A LA DETERMINACIÓN DE BIOMARCADORES
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-ShareAlike 4.0 International
http://creativecommons.org/licenses/by-nc-sa/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-ShareAlike 4.0 International
http://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:e_Buah Biblioteca Digital Universidad de Alcalá
instname:Universidad de Alcalá (UAH)
instname_str Universidad de Alcalá (UAH)
reponame_str e_Buah Biblioteca Digital Universidad de Alcalá
collection e_Buah Biblioteca Digital Universidad de Alcalá
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repository.mail.fl_str_mv
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