Embeddability of Kimura 3ST Markov matrices

In this note, we characterize the embeddability of generic Kimura 3ST Markov matrices in terms of their eigenvalues. As a consequence, we are able to compute the volume of such matrices relative to the volume of all Markov matrices within the model. We also provide examples showing that, in general,...

Descripción completa

Detalles Bibliográficos
Autores: Roca Lacostena, Jordi|||0000-0003-1651-9504, Fernández Sánchez, Jesús|||0000-0002-7062-8042
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/192336
Acceso en línea:https://hdl.handle.net/2117/192336
https://dx.doi.org/10.1016/j.jtbi.2018.02.005
Access Level:acceso abierto
Palabra clave:Markov processes
Markov matrix
Markov generator
Eigenvalues
Evolutionary model
Embeddability
Markov, Processos de
Àrees temàtiques de la UPC::Matemàtiques i estadística::Topologia::Topologia algebraica
Descripción
Sumario:In this note, we characterize the embeddability of generic Kimura 3ST Markov matrices in terms of their eigenvalues. As a consequence, we are able to compute the volume of such matrices relative to the volume of all Markov matrices within the model. We also provide examples showing that, in general, mutation rates are not identifiable from substitution probabilities. These examples also illustrate that symmetries between mutation probabilities do not necessarily arise from symmetries between the corresponding mutation rates.