Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson’s disease: Synthesis, in vitro and in vivo studies

Monoamine oxidase B (MAO-B) inhibitors are still receiving great attention as promising therapeutic agents for central nervous system disorders. This study explores, for the first time, the potential of 3-thiophenylcoumarins as in vitro and in vivo agents against Parkinsońs disease

Detalles Bibliográficos
Autores: Rodríguez Enríquez, Fernanda, Viña Castelao, María Dolores, Uriarte Villares, Eugenio, Fontenla Gil, José Ángel, Matos, Maria João Correia Pinto Carvalho de
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/32010
Acceso en línea:http://hdl.handle.net/10347/32010
Access Level:acceso abierto
Palabra clave:Investigación
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Descripción
Sumario:Monoamine oxidase B (MAO-B) inhibitors are still receiving great attention as promising therapeutic agents for central nervous system disorders. This study explores, for the first time, the potential of 3-thiophenylcoumarins as in vitro and in vivo agents against Parkinsońs disease