Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson’s disease: Synthesis, in vitro and in vivo studies

Monoamine oxidase B (MAO-B) inhibitors are still receiving great attention as promising therapeutic agents for central nervous system disorders. This study explores, for the first time, the potential of 3-thiophenylcoumarins as in vitro and in vivo agents against Parkinsońs disease

Bibliographic Details
Authors: Rodríguez Enríquez, Fernanda, Viña Castelao, María Dolores, Uriarte Villares, Eugenio, Fontenla Gil, José Ángel, Matos, Maria João Correia Pinto Carvalho de
Format: article
Publication Date:2020
Country:España
Institution:Universidad de Santiago de Compostela (USC)
Repository:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Language:English
OAI Identifier:oai:minerva.usc.gal:10347/32010
Online Access:http://hdl.handle.net/10347/32010
Access Level:Open access
Keyword:Investigación
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Description
Summary:Monoamine oxidase B (MAO-B) inhibitors are still receiving great attention as promising therapeutic agents for central nervous system disorders. This study explores, for the first time, the potential of 3-thiophenylcoumarins as in vitro and in vivo agents against Parkinsońs disease

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