Spacer-mediated synthesis of bis-spiroketal disaccharides: Nonsymmetrical furanose-pyranose difructose dianhydrides

The stereochemical outcome of the dimerization reaction of D-fructose, leading to tricyclic bis-spiroketal systems, can be tuned by inserting a xylylene template between the reacting moieties. Spirocyclization becomes then an intramolecular process, the available conformational space depending on th...

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Detalles Bibliográficos
Autores: Louis, Farida F., García Moreno, M. Isabel, Balbuena Oliva, Patricia, Ortiz Mellet, Carmen, García Fernández, José Manuel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2007
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/70295
Acceso en línea:https://hdl.handle.net/11441/70295
https://doi.org/10.1055/s-2007-991055
Access Level:acceso abierto
Palabra clave:Acetals
Difructose dianhydrides
Oligosaccharides
Spiro compounds
Spiroacetals
Descripción
Sumario:The stereochemical outcome of the dimerization reaction of D-fructose, leading to tricyclic bis-spiroketal systems, can be tuned by inserting a xylylene template between the reacting moieties. Spirocyclization becomes then an intramolecular process, the available conformational space depending on the nature of the tether. The methodology is here illustrated by the stereoselective synthesis of two nonsymmetrical di-D-fructose dianhydrides present in commercial caramel