Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose

Bifidogenic effect and stimulation of short chain fatty acid (SCFA) production by fractions of oligosaccharides with a DP≥3 and Gal β(1-6) linkages synthesised from lactose or lactulose by Pectinex Ultra SP-L and Lactozym 3000 L HP G were evaluated in human faecal slurries. Results were compared wit...

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Autores: Cardelle-Cobas, Alejandra, Fernández García, María, Salazar, Nuria, Martínez-Villaluenga, Cristina, Villamiel, Mar, Ruas-Madiedo, Patricia, González de los Reyes-Gavilán, Clara
Tipo de recurso: artículo
Fecha de publicación:2009
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/50593
Acceso en línea:http://hdl.handle.net/10261/50593
Access Level:acceso abierto
Palabra clave:Oligosaccharides
Bifidogenic effect
Short chain fatty acids
Lactose
Lactulose
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spelling Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactuloseCardelle-Cobas, AlejandraFernández García, MaríaSalazar, NuriaMartínez-Villaluenga, CristinaVillamiel, MarRuas-Madiedo, PatriciaGonzález de los Reyes-Gavilán, ClaraOligosaccharidesBifidogenic effectShort chain fatty acidsLactoseLactuloseBifidogenic effect and stimulation of short chain fatty acid (SCFA) production by fractions of oligosaccharides with a DP≥3 and Gal β(1-6) linkages synthesised from lactose or lactulose by Pectinex Ultra SP-L and Lactozym 3000 L HP G were evaluated in human faecal slurries. Results were compared with those obtained for the commercial oligosaccharide mixture Vivinal®-GOS. Quantitative real-time PCR showed that all galacto-oligosaccharide (GOS) fractions stimulated slightly higher bifidobacteria growth than lactose, lactulose and Vivinal®-GOS. GOS fractions promoted the production of total SCFA and acetic acid in a similar way to Vivinal®-GOS and more than glucose, lactose and lactulose. In conclusion, oligosaccharides derived from lactose and lactulose may represent a suitable alternative to lactulose for the design of new functional food ingredients. © Proprietors of Journal of Dairy Research 2009.The authors thank the Spanish Ministry of Education and Science (Projects Consolider Ingenio 2010 FUN-C-FOOD 2007-00063 and AGL2007-62736) and Community of Madrid (project ALIBIRD-CM S-0505/AGR-000153) for financial support. Alejandra Cardelle-Cobas and Nuria Salazar thank their predoctoral FPU and FPI grants, respectively, from the Spanish Ministry of Education and Science.Peer ReviewedCambridge University PressMinisterio de Educación y Ciencia (España)Comunidad de Madrid2012201220092012info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://hdl.handle.net/10261/50593reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglésinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/505932026-05-22T06:33:51Z
dc.title.none.fl_str_mv Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose
title Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose
spellingShingle Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose
Cardelle-Cobas, Alejandra
Oligosaccharides
Bifidogenic effect
Short chain fatty acids
Lactose
Lactulose
title_short Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose
title_full Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose
title_fullStr Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose
title_full_unstemmed Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose
title_sort Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose
dc.creator.none.fl_str_mv Cardelle-Cobas, Alejandra
Fernández García, María
Salazar, Nuria
Martínez-Villaluenga, Cristina
Villamiel, Mar
Ruas-Madiedo, Patricia
González de los Reyes-Gavilán, Clara
author Cardelle-Cobas, Alejandra
author_facet Cardelle-Cobas, Alejandra
Fernández García, María
Salazar, Nuria
Martínez-Villaluenga, Cristina
Villamiel, Mar
Ruas-Madiedo, Patricia
González de los Reyes-Gavilán, Clara
author_role author
author2 Fernández García, María
Salazar, Nuria
Martínez-Villaluenga, Cristina
Villamiel, Mar
Ruas-Madiedo, Patricia
González de los Reyes-Gavilán, Clara
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Educación y Ciencia (España)
Comunidad de Madrid
dc.subject.none.fl_str_mv Oligosaccharides
Bifidogenic effect
Short chain fatty acids
Lactose
Lactulose
topic Oligosaccharides
Bifidogenic effect
Short chain fatty acids
Lactose
Lactulose
description Bifidogenic effect and stimulation of short chain fatty acid (SCFA) production by fractions of oligosaccharides with a DP≥3 and Gal β(1-6) linkages synthesised from lactose or lactulose by Pectinex Ultra SP-L and Lactozym 3000 L HP G were evaluated in human faecal slurries. Results were compared with those obtained for the commercial oligosaccharide mixture Vivinal®-GOS. Quantitative real-time PCR showed that all galacto-oligosaccharide (GOS) fractions stimulated slightly higher bifidobacteria growth than lactose, lactulose and Vivinal®-GOS. GOS fractions promoted the production of total SCFA and acetic acid in a similar way to Vivinal®-GOS and more than glucose, lactose and lactulose. In conclusion, oligosaccharides derived from lactose and lactulose may represent a suitable alternative to lactulose for the design of new functional food ingredients. © Proprietors of Journal of Dairy Research 2009.
publishDate 2009
dc.date.none.fl_str_mv 2009
2012
2012
2012
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/50593
url http://hdl.handle.net/10261/50593
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Cambridge University Press
publisher.none.fl_str_mv Cambridge University Press
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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