Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia: a population-based study

MPOC; Atenció primària; Tractament

Detalhes bibliográficos
Autores: Roset, Montse, Rodriguez-Blanco, Teresa, Muñoz, Laura, Miravitlles Fernández, Marc, Monteagudo, Mònica
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Recursos:Departament de Salut de la Generalitat de Catalunya (DS)
Repositorio:Scientia. Dipòsit d'Informació Digital del Departament de Salut
OAI Identifier:oai:scientiasalut.gencat.cat:11351/5895
Acesso em linha:https://hdl.handle.net/11351/5895
Access Level:acceso abierto
Palavra-chave:Pulmons - Malalties obstructives
Atenció primària - Catalunya
DISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic Obstructive
Other subheadings::Other subheadings::Other subheadings::/drug therapy
PUBLIC HEALTH::Environmental Health::Health::Health Services::Primary Health Care
GEOGRAPHICALS::Geographic Locations::Europe::Spain
ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares obstructivas::enfermedad pulmonar obstructiva crónica
Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia
SALUD PÚBLICA::salud ambiental::salud::servicios de salud::atención primaria de la salud
DENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::Europa (continente)::España
id ES_c2da076e4e28769aef890693c4d96795
oai_identifier_str oai:scientiasalut.gencat.cat:11351/5895
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia: a population-based study
title Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia: a population-based study
spellingShingle Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia: a population-based study
Roset, Montse
Pulmons - Malalties obstructives
Atenció primària - Catalunya
DISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic Obstructive
Other subheadings::Other subheadings::Other subheadings::/drug therapy
PUBLIC HEALTH::Environmental Health::Health::Health Services::Primary Health Care
GEOGRAPHICALS::Geographic Locations::Europe::Spain
ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares obstructivas::enfermedad pulmonar obstructiva crónica
Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia
SALUD PÚBLICA::salud ambiental::salud::servicios de salud::atención primaria de la salud
DENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::Europa (continente)::España
title_short Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia: a population-based study
title_full Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia: a population-based study
title_fullStr Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia: a population-based study
title_full_unstemmed Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia: a population-based study
title_sort Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia: a population-based study
dc.creator.none.fl_str_mv Roset, Montse
Rodriguez-Blanco, Teresa
Muñoz, Laura
Miravitlles Fernández, Marc
Monteagudo, Mònica
author Roset, Montse
author_facet Roset, Montse
Rodriguez-Blanco, Teresa
Muñoz, Laura
Miravitlles Fernández, Marc
Monteagudo, Mònica
author_role author
author2 Rodriguez-Blanco, Teresa
Muñoz, Laura
Miravitlles Fernández, Marc
Monteagudo, Mònica
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Institut Català de la Salut
[Monteagudo M, Rodriguez-Blanco T] Primary Care University Research Institute Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Roset M] IMS Health, Barcelona, Spain. [Muñoz L] Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS), Barcelona, Spain. [Miravitlles M] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, Spain.
Vall d'Hebron Barcelona Hospital Campus
dc.subject.none.fl_str_mv Pulmons - Malalties obstructives
Atenció primària - Catalunya
DISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic Obstructive
Other subheadings::Other subheadings::Other subheadings::/drug therapy
PUBLIC HEALTH::Environmental Health::Health::Health Services::Primary Health Care
GEOGRAPHICALS::Geographic Locations::Europe::Spain
ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares obstructivas::enfermedad pulmonar obstructiva crónica
Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia
SALUD PÚBLICA::salud ambiental::salud::servicios de salud::atención primaria de la salud
DENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::Europa (continente)::España
topic Pulmons - Malalties obstructives
Atenció primària - Catalunya
DISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic Obstructive
Other subheadings::Other subheadings::Other subheadings::/drug therapy
PUBLIC HEALTH::Environmental Health::Health::Health Services::Primary Health Care
GEOGRAPHICALS::Geographic Locations::Europe::Spain
ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares obstructivas::enfermedad pulmonar obstructiva crónica
Otros calificadores::Otros calificadores::Otros calificadores::/farmacoterapia
SALUD PÚBLICA::salud ambiental::salud::servicios de salud::atención primaria de la salud
DENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::Europa (continente)::España
description MPOC; Atenció primària; Tractament
publishDate 2017
dc.date.none.fl_str_mv 2017
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11351/5895
url https://hdl.handle.net/11351/5895
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv International Journal of Chronic Obstructive Pulmonary Disease;12
https://www.dovepress.com/characteristics-of-copd-patients-initiating-treatment-with-aclidinium--peer-reviewed-article-COPD
dc.rights.none.fl_str_mv Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Dove Medical Press
publisher.none.fl_str_mv Dove Medical Press
dc.source.none.fl_str_mv Scientia
reponame:Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname:Departament de Salut de la Generalitat de Catalunya (DS)
instname_str Departament de Salut de la Generalitat de Catalunya (DS)
reponame_str Scientia. Dipòsit d'Informació Digital del Departament de Salut
collection Scientia. Dipòsit d'Informació Digital del Departament de Salut
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869418723221176320
spelling Characteristics of COPD patients initiating treatment with aclidinium or tiotropium in primary care in Catalonia: a population-based studyRoset, MontseRodriguez-Blanco, TeresaMuñoz, LauraMiravitlles Fernández, MarcMonteagudo, MònicaPulmons - Malalties obstructivesAtenció primària - CatalunyaDISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic ObstructiveOther subheadings::Other subheadings::Other subheadings::/drug therapyPUBLIC HEALTH::Environmental Health::Health::Health Services::Primary Health CareGEOGRAPHICALS::Geographic Locations::Europe::SpainENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares obstructivas::enfermedad pulmonar obstructiva crónicaOtros calificadores::Otros calificadores::Otros calificadores::/farmacoterapiaSALUD PÚBLICA::salud ambiental::salud::servicios de salud::atención primaria de la saludDENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::Europa (continente)::EspañaMPOC; Atenció primària; TractamentEPOC; Atención primaria; TratamientoCOPD; Primary care; TreatmentObjective: To describe and compare demographic and clinical profile of patients newly initiated on aclidinium (ACL) or tiotropium (TIO) and identify factors associated with newly initiated ACL in real-life clinical practice during 2013 in Catalonia. Design: We performed a population-based, retrospective, observational study with data obtained from the Information System for Research Development in Primary Care, a population database that contains information of 5.8 million inhabitants (more than 80% of the Catalan population). Patients over 40 years old, with a recorded diagnosis of COPD and newly initiated treatment with either ACL or TIO during the study period (January to December 2013), were selected. A descriptive analysis of demographic and clinical characteristics was performed, and treatment adherence was also assessed for both cohorts. Results: A total of 8,863 individuals were identified, 4,293 initiated with ACL and 4,570 with TIO. They had a mean age of 69.4 years (standard deviation: 11.3), a median COPD duration of 3 years (interquartile range: 0–8), and 71% were males. Patients treated with ACL were older, with more respiratory comorbidities, a longer time since COPD diagnosis, worse forced expiratory volume in 1 second (% predicted), and with a higher rate of exacerbations during the previous year compared with TIO. It was found that 41.3% of patients with ACL and 62.3% of patients with TIO had no previous COPD treatment. Inhaled corticosteroid and long-acting β2-agonist were the most frequent concomitant medications (32.9% and 32.6%, respectively). Approximately 75% of patients were persistent with ACL or TIO at 3 months from the beginning of treatment, and more than 50% of patients remained persistent at 9 months. Conclusion: Patients initiated with ACL had more severe COPD and were taking more concomitant respiratory medications than patients initiated with TIO. ACL was more frequently initiated as part of triple therapy, while TIO was more frequently initiated as monotherapy.The current study has been funded by an unrestricted grant from AstraZeneca UK Limited.Dove Medical PressInstitut Català de la Salut[Monteagudo M, Rodriguez-Blanco T] Primary Care University Research Institute Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Roset M] IMS Health, Barcelona, Spain. [Muñoz L] Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS), Barcelona, Spain. [Miravitlles M] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, Spain.Vall d'Hebron Barcelona Hospital Campus202120212017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/11351/5895Scientiareponame:Scientia. Dipòsit d'Informació Digital del Departament de Salutinstname:Departament de Salut de la Generalitat de Catalunya (DS)InglésInternational Journal of Chronic Obstructive Pulmonary Disease;12https://www.dovepress.com/characteristics-of-copd-patients-initiating-treatment-with-aclidinium--peer-reviewed-article-COPDAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:scientiasalut.gencat.cat:11351/58952026-06-12T09:38:37Z
score 15,812429

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