Diagnóstico de infecciones nosocomiales en niños tras cirugía cardíaca: comparación de un test molecular con hemocultivos convencionales
Nosocomial infections are a prevalent cause of death and complications in critically ill children, especially bloodstream infections (BSI). Complex congenital heart diseases (CHD) require surgical or interventionist treatment, often in neonatal period, with posterior admission in Pediatric Critical...
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| Formato: | tesis doctoral |
| Fecha de publicación: | 2025 |
| País: | España |
| Recursos: | Universidad Complutense de Madrid (UCM) |
| Repositorio: | Docta Complutense |
| Idioma: | español |
| OAI Identifier: | oai:docta.ucm.es:20.500.14352/119051 |
| Acesso em linha: | https://hdl.handle.net/20.500.14352/119051 |
| Access Level: | acceso abierto |
| Palavra-chave: | 616-022.1:614.2(1-21)(043.2) Infecciones nosocomiales Enfermedades infecciosas 3205.05 Enfermedades Infecciosas |
| Resumo: | Nosocomial infections are a prevalent cause of death and complications in critically ill children, especially bloodstream infections (BSI). Complex congenital heart diseases (CHD) require surgical or interventionist treatment, often in neonatal period, with posterior admission in Pediatric Critical Care Units (PICU) and these patients have a high risk of nosocomial infection. Conventional blood cultures are able to detect only up to 25% of BSI in children with clinical and analytical signs of invasive bacterial infection. Several studies have suggested that molecular tests, such a multiple polymerase chain reaction (PCR), could be a faster and more effective tool for detection of bacterial infections. However, there is a lack of studies comparing molecular tests with conventional cultures in hospital-acquired infections, especially in pediatric population... |
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