A note on linkage between the angora and fgf5 genes in rabbits

[EN] The angora mutation in mice corresponds to a large deletion in the fgf5 (fibroblast growth factor 5) exon 1. Two pairs of primers were chosen in the human fgf5 coding sequence in order to amplify two fragments of the rabbit gene. One biallelic polymorphism was demonstrated in each fragment. The...

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Detalles Bibliográficos
Autores: Mulsant, P., Rochambeau, H. de, Thébault, R.G.
Tipo de recurso: artículo
Fecha de publicación:2004
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/9926
Acceso en línea:https://riunet.upv.es/handle/10251/9926
Access Level:acceso abierto
Palabra clave:Rabbit
Angora gene
Mice
Fibroblast growth factor 5 gene
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repository_id_str
spelling A note on linkage between the angora and fgf5 genes in rabbitsMulsant, P.Rochambeau, H. deThébault, R.G.RabbitAngora geneMiceFibroblast growth factor 5 gene[EN] The angora mutation in mice corresponds to a large deletion in the fgf5 (fibroblast growth factor 5) exon 1. Two pairs of primers were chosen in the human fgf5 coding sequence in order to amplify two fragments of the rabbit gene. One biallelic polymorphism was demonstrated in each fragment. The four alleles were cloned and sequenced. A random sample of unrelated angora (n=17) and wild-type control animals (n=15) were analysed for both polymorphisms. The observed haplotype frequencies show a clear separation between the two populations. Informative families were created by backcrossing to measure linkage between the angora and fgf5 loci. No recombinant was observed between them, in 56 meiosis, proving a tight linkage between both genes.World Rabbit Science. ICTA. UPVRepositorio Institucional de la Universitat Politècnica de València Riunet20042004-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://riunet.upv.es/handle/10251/9926reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Reserva de todos los derechoshttp://rightsstatements.org/vocab/InC/1.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/99262026-06-13T07:49:27Z
dc.title.none.fl_str_mv A note on linkage between the angora and fgf5 genes in rabbits
title A note on linkage between the angora and fgf5 genes in rabbits
spellingShingle A note on linkage between the angora and fgf5 genes in rabbits
Mulsant, P.
Rabbit
Angora gene
Mice
Fibroblast growth factor 5 gene
title_short A note on linkage between the angora and fgf5 genes in rabbits
title_full A note on linkage between the angora and fgf5 genes in rabbits
title_fullStr A note on linkage between the angora and fgf5 genes in rabbits
title_full_unstemmed A note on linkage between the angora and fgf5 genes in rabbits
title_sort A note on linkage between the angora and fgf5 genes in rabbits
dc.creator.none.fl_str_mv Mulsant, P.
Rochambeau, H. de
Thébault, R.G.
author Mulsant, P.
author_facet Mulsant, P.
Rochambeau, H. de
Thébault, R.G.
author_role author
author2 Rochambeau, H. de
Thébault, R.G.
author2_role author
author
dc.contributor.none.fl_str_mv Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv Rabbit
Angora gene
Mice
Fibroblast growth factor 5 gene
topic Rabbit
Angora gene
Mice
Fibroblast growth factor 5 gene
description [EN] The angora mutation in mice corresponds to a large deletion in the fgf5 (fibroblast growth factor 5) exon 1. Two pairs of primers were chosen in the human fgf5 coding sequence in order to amplify two fragments of the rabbit gene. One biallelic polymorphism was demonstrated in each fragment. The four alleles were cloned and sequenced. A random sample of unrelated angora (n=17) and wild-type control animals (n=15) were analysed for both polymorphisms. The observed haplotype frequencies show a clear separation between the two populations. Informative families were created by backcrossing to measure linkage between the angora and fgf5 loci. No recombinant was observed between them, in 56 meiosis, proving a tight linkage between both genes.
publishDate 2004
dc.date.none.fl_str_mv 2004
2004-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/9926
url https://riunet.upv.es/handle/10251/9926
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reserva de todos los derechos
http://rightsstatements.org/vocab/InC/1.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reserva de todos los derechos
http://rightsstatements.org/vocab/InC/1.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv World Rabbit Science. ICTA. UPV
publisher.none.fl_str_mv World Rabbit Science. ICTA. UPV
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869418665943760896
score 15.301603

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