Single-pixel Computational Imaging: Application to Fluorescence and Diffuse Optical Imaging

In this dissertation, we demonstrate the use of single-pixel imaging methods in two important imaging modalities in biomedical applications, time-resolved fluorescence imaging and diffuse optical imaging. In fluorescence imaging, we apply a novel method based on data fusion to acquire giga-voxel 4D...

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Detalles Bibliográficos
Autor: Lenz, Armin
Tipo de recurso: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:CBUC, CESCA
Repositorio:TDR. Tesis Doctorales en Red
OAI Identifier:oai:www.tdx.cat:10803/690418
Acceso en línea:http://hdl.handle.net/10803/690418
http://dx.doi.org/10.6035/14104.2024.716126
Access Level:acceso abierto
Palabra clave:Single-pixel imaging
Computational imaging
Fluorescence imaging
Diffuse optical imaging
Spatial frequency domain imaging
Fluorescence lifetime imaging
Ciències
53
535
Descripción
Sumario:In this dissertation, we demonstrate the use of single-pixel imaging methods in two important imaging modalities in biomedical applications, time-resolved fluorescence imaging and diffuse optical imaging. In fluorescence imaging, we apply a novel method based on data fusion to acquire giga-voxel 4D hypercubes by measuring only a very small fraction of the dataset. The proposed systems combine conventional cameras with multispectral, time-resolved single-pixel cameras, and data fusion is used to merge the 2D and projections generated by each individual camera into a high-resolution 4D hypercube. In the area of diffuse optical imaging, novel systems based on single-pixel imaging techniques have been developed, allowing the use of simplified detection schemes using integrating spheres as bucket detectors.