Major dietary patterns and risk of frailty in older adults: A prospective cohort study
Background: There is emerging evidence of the role of certain nutrients as risk factors for frailty. However, people eat food, rather than nutrients, and no previous study has examined the association between dietary patterns empirically derived from food consumption and the risk of frailty in older...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2015 |
| País: | España |
| Institución: | Universidad Autónoma de Madrid |
| Repositorio: | Biblos-e Archivo. Repositorio Institucional de la UAM |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.uam.es:10486/672210 |
| Acceso en línea: | http://hdl.handle.net/10486/672210 https://dx.doi.org/10.1186/s12916-014-0255-6 |
| Access Level: | acceso abierto |
| Palabra clave: | Cohort study Diet Frailty Older adults Spain Medicina |
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Major dietary patterns and risk of frailty in older adults: A prospective cohort studyLeón-Muñoz, Luz MaríaGarcía García-Esquinas, EstherLópez García, EstherBanegas Banegas, José RamónRodríguez Artalejo, FernandoCohort studyDietFrailtyOlder adultsSpainMedicinaBackground: There is emerging evidence of the role of certain nutrients as risk factors for frailty. However, people eat food, rather than nutrients, and no previous study has examined the association between dietary patterns empirically derived from food consumption and the risk of frailty in older adults. Methods: This is a prospective cohort study of 1,872 non-institutionalized individuals aged ≥60 years recruited between 2008 and 2010. At baseline, food consumption was obtained with a validated diet history and, by using factor analysis, two dietary patterns were identified: a ‘prudent’ pattern, characterized by high intake of olive oil and vegetables, and a ‘Westernized’ pattern, with a high intake of refined bread, whole dairy products, and red and processed meat, as well as low consumption of fruit and vegetables. Participants were followed-up until 2012 to assess incident frailty, defined as at least three of the five Fried criteria (exhaustion, weakness, low physical activity, slow walking speed, and unintentional weight loss). Results: Over a 3.5-year follow-up, 96 cases of incident frailty were ascertained. The multivariate odds ratios (95% confidence interval) of frailty among those in the first (lowest), second, and third tertile of adherence to the prudent dietary pattern were 1, 0.64 (0.37–1.12), and 0.40 (0.2–0.81), respectively; P-trend = 0.009. The corresponding values for the Westernized pattern were 1, 1.53 (0.85–2.75), and 1.61 (0.85–3.03); P-trend = 0.14. Moreover, a greater adherence to the Westernized pattern was associated with an increasing risk of slow walking speed and weight loss. Conclusions: In older adults, a prudent dietary pattern showed an inverse dose-response relationship with the risk of frailty while a Westernized pattern had a direct relationship with some of their components. Clinical trials should test whether a prudent pattern is effective in preventing or delaying frailtyBaseline data collection was funded by Sanofi-Aventis. Data collection during follow-up was funded by the Spanish Government grants 09/1626 and 09/0104 (Ministry of Health of Spain). Funding specific for this analysis was obtained from the Spanish Government grant 12/1166 (Ministry of Health of Spain) and the FP7-HEALTH-2012-Proposal No: 305483–2 (FRAILOMIC Initiative). Funders had no role in data analyses, preparation of the manuscript, or in the decision to submit it for publicationBioMed CentralDepartamento de Medicina Preventiva y Salud Pública y MicrobiologíaFacultad de Medicina20152015-01-20research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10486/672210https://dx.doi.org/10.1186/s12916-014-0255-6reponame:Biblos-e Archivo. Repositorio Institucional de la UAMinstname:Universidad Autónoma de MadridInglésengEuropean Commission http://dx.doi.org/10.13039/501100000780 Framework Programme Seven 305483open accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:repositorio.uam.es:10486/6722102026-06-23T12:46:27Z |
| dc.title.none.fl_str_mv |
Major dietary patterns and risk of frailty in older adults: A prospective cohort study |
| title |
Major dietary patterns and risk of frailty in older adults: A prospective cohort study |
| spellingShingle |
Major dietary patterns and risk of frailty in older adults: A prospective cohort study León-Muñoz, Luz María Cohort study Diet Frailty Older adults Spain Medicina |
| title_short |
Major dietary patterns and risk of frailty in older adults: A prospective cohort study |
| title_full |
Major dietary patterns and risk of frailty in older adults: A prospective cohort study |
| title_fullStr |
Major dietary patterns and risk of frailty in older adults: A prospective cohort study |
| title_full_unstemmed |
Major dietary patterns and risk of frailty in older adults: A prospective cohort study |
| title_sort |
Major dietary patterns and risk of frailty in older adults: A prospective cohort study |
| dc.creator.none.fl_str_mv |
León-Muñoz, Luz María García García-Esquinas, Esther López García, Esther Banegas Banegas, José Ramón Rodríguez Artalejo, Fernando |
| author |
León-Muñoz, Luz María |
| author_facet |
León-Muñoz, Luz María García García-Esquinas, Esther López García, Esther Banegas Banegas, José Ramón Rodríguez Artalejo, Fernando |
| author_role |
author |
| author2 |
García García-Esquinas, Esther López García, Esther Banegas Banegas, José Ramón Rodríguez Artalejo, Fernando |
| author2_role |
author author author author |
| dc.contributor.none.fl_str_mv |
Departamento de Medicina Preventiva y Salud Pública y Microbiología Facultad de Medicina |
| dc.subject.none.fl_str_mv |
Cohort study Diet Frailty Older adults Spain Medicina |
| topic |
Cohort study Diet Frailty Older adults Spain Medicina |
| description |
Background: There is emerging evidence of the role of certain nutrients as risk factors for frailty. However, people eat food, rather than nutrients, and no previous study has examined the association between dietary patterns empirically derived from food consumption and the risk of frailty in older adults. Methods: This is a prospective cohort study of 1,872 non-institutionalized individuals aged ≥60 years recruited between 2008 and 2010. At baseline, food consumption was obtained with a validated diet history and, by using factor analysis, two dietary patterns were identified: a ‘prudent’ pattern, characterized by high intake of olive oil and vegetables, and a ‘Westernized’ pattern, with a high intake of refined bread, whole dairy products, and red and processed meat, as well as low consumption of fruit and vegetables. Participants were followed-up until 2012 to assess incident frailty, defined as at least three of the five Fried criteria (exhaustion, weakness, low physical activity, slow walking speed, and unintentional weight loss). Results: Over a 3.5-year follow-up, 96 cases of incident frailty were ascertained. The multivariate odds ratios (95% confidence interval) of frailty among those in the first (lowest), second, and third tertile of adherence to the prudent dietary pattern were 1, 0.64 (0.37–1.12), and 0.40 (0.2–0.81), respectively; P-trend = 0.009. The corresponding values for the Westernized pattern were 1, 1.53 (0.85–2.75), and 1.61 (0.85–3.03); P-trend = 0.14. Moreover, a greater adherence to the Westernized pattern was associated with an increasing risk of slow walking speed and weight loss. Conclusions: In older adults, a prudent dietary pattern showed an inverse dose-response relationship with the risk of frailty while a Westernized pattern had a direct relationship with some of their components. Clinical trials should test whether a prudent pattern is effective in preventing or delaying frailty |
| publishDate |
2015 |
| dc.date.none.fl_str_mv |
2015 2015-01-20 |
| dc.type.none.fl_str_mv |
research article http://purl.org/coar/resource_type/c_2df8fbb1 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
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article |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10486/672210 https://dx.doi.org/10.1186/s12916-014-0255-6 |
| url |
http://hdl.handle.net/10486/672210 https://dx.doi.org/10.1186/s12916-014-0255-6 |
| dc.language.none.fl_str_mv |
Inglés eng |
| language_invalid_str_mv |
Inglés |
| language |
eng |
| dc.relation.none.fl_str_mv |
European Commission http://dx.doi.org/10.13039/501100000780 Framework Programme Seven 305483 |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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application/pdf |
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BioMed Central |
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BioMed Central |
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reponame:Biblos-e Archivo. Repositorio Institucional de la UAM instname:Universidad Autónoma de Madrid |
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Universidad Autónoma de Madrid |
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Biblos-e Archivo. Repositorio Institucional de la UAM |
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