LPS priming before plaque deposition impedes microglial activation and restrains Aβ pathology in the 5xFAD mouse model of Alzheimer’s disease

© 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Detalhes bibliográficos
Autores: Yang, Yiyi, García-Cruzado, Marta, Zeng, Hairuo, Camprubí-Ferrer, Lluís, Bahatyrevich-Kharitonik, Bazhena, Bachiller, Sara, Deierborg, Tomas
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/351402
Acesso em linha:http://hdl.handle.net/10261/351402
Access Level:acceso abierto
Palavra-chave:LPS
Priming
Innate immune memory
Microglia
β-amyloid pathology
Neuroinflammation
Long-term effects
Systemic inflammation
Proteomics
Descrição
Resumo:© 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).