Long-Term Results of Segmentectomy vs. Lobectomy for c-Stage IA Lung Cancer: A Real-Life Study with a Propensity Score Analysis Based on a National Cohort.

The objective was to compare the results of segmentectomy and lobectomy in the treatment of c-stage IA lung cancer in terms of tumor recurrence and 5-year survival. Methods: An observational study was performed using 3533 patients included in the registry of the Spanish VATS Group (GEVATS) of the Sp...

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Detalles Bibliográficos
Autores: López, I. (Iker)|||/items/5ba4b5c0-5eb6-4785-a623-57c1dacec1e8, Aguinagalde, B. (Borja)|||/items/610953dd-f873-4f89-b1e3-9e952fd4e058, Ferrer-Bonsoms, J.A. (Juan Ángel)|||/items/cfd30c63-00b2-4b7d-8deb-f34472a86ee5, Sánchez, L. (Laura)|||/items/4afdde88-1a11-466a-987b-591e9f3f9458, Ascanio, F. (Fernando)|||/items/59825ea5-da29-41ef-922f-af10e52b8517, Sesma, J. (Julio)|||/items/f7448c35-74bb-454f-94a7-06ef3d91bbd6, Recuero, J.L. (José Luís)|||/items/358588f0-6b7c-457d-94b2-37a399abef9b, Fernández-Monje, A. (Arantza)|||/items/2cc94d73-64a6-4927-8b99-b871162122ac, Embun, R. (Raúl)|||/items/07836388-99d0-4054-88fd-bb2aa78d90e0
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/117230
Acceso en línea:https://hdl.handle.net/10171/117230
Access Level:acceso abierto
Palabra clave:Lung cancer
Segmentectomy
Lobectomy
Sublobar resection
Recurrence
Survival
Descripción
Sumario:The objective was to compare the results of segmentectomy and lobectomy in the treatment of c-stage IA lung cancer in terms of tumor recurrence and 5-year survival. Methods: An observational study was performed using 3533 patients included in the registry of the Spanish VATS Group (GEVATS) of the Spanish Society of Thoracic Surgery (SECT) between 2016 and 2018. A total of 1004 lobectomies and 83 segmentectomies in c-stage IA were selected. Two comparable groups were selected through 2:1 propensity score matching with patient-, tumor- and surgery-related variables, leaving 166 lobectomies and 83 segmentectomies. Tumor recurrence was analyzed by Fisher’s test and overall, cancer-specific, recurrence-free and disease-free survival by Kaplan-Meier and Log-rank tests. Results: Overall recurrence was 23.7% in both groups, with a predominance of locoregional recurrence in segmentectomy (16.2% vs. 11.2%) and distant recurrence in lobectomy (12.5% vs. 7.5%). There was no difference between the two groups in any of the survival types. Overall survival at 5 years was 73.5% (95% CI: 65.5–82.4%) in the lobectomy group vs. 73.1% (95% CI: 60.1–88.9%) in the segmentectomy group. Conclusions: Anatomic segmentectomy may be a valid option in the treatment of c-stage IA lung cancer since the recurrence and long-term survival outcomes compared to lobectomy are equivalent.

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