Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity

A novel perspective of the function of carotenoids and carotenoid-derived products - including, but not restricted to, the retinoids - is emerging in recent years which connects these compounds to the control of adipocyte biology and body fat accumulation, with implications for the management of obe...

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Autores: Luisa Bonet, M., Canas, Jose A., Ribot, Joan, Palou, Andreu
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Conselleria de Salut i Consum del Govern de les Illes Balears
Repositorio:Docusalut
Idioma:inglés
OAI Identifier:oai:docusalut.com:20.500.13003/17317
Acceso en línea:https://hdl.handle.net/20.500.13003/17317
Access Level:acceso abierto
Palabra clave:Humans
Obesity
Carotenoids
Adiposity
Animals
Adipocytes
Adipogenesis
Adipocitos
Obesidad
Humanos
Animales
Adipogénesis
Adiposidad
Carotenoides
Apocarotenoids
Energy metabolism
White adipose tissue browning
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spelling Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesityLuisa Bonet, M.Canas, Jose A.Ribot, JoanPalou, AndreuHumansObesityCarotenoidsAdiposityAnimalsAdipocytesAdipogenesisAdipocitosObesidadHumanosAnimalesAdipogénesisAdiposidadCarotenoidesCarotenoidsApocarotenoidsObesityAdiposityEnergy metabolismWhite adipose tissue browningA novel perspective of the function of carotenoids and carotenoid-derived products - including, but not restricted to, the retinoids - is emerging in recent years which connects these compounds to the control of adipocyte biology and body fat accumulation, with implications for the management of obesity, diabetes and cardiovascular disease. Cell and animal studies indicate that carotenoids and carotenoids derivatives can reduce adiposity and impact key aspects of adipose tissue biology including adipocyte differentiation, hypertrophy, capacity for fatty acid oxidation and thermogenesis (including browning of white adipose tissue) and secretory function. Epidemiological studies in humans associate higher dietary intakes and serum levels of carotenoids with decreased adiposity. Specifically designed human intervention studies, though still sparse, indicate a beneficial effect of carotenoid supplementation in the accrual of abdominal adiposity. The objective of this review is to summarize recent findings in this area, place them in physiological contexts, and provide likely regulatory schemes whenever possible. The focus will be on the effects of carotenoids as nutritional regulators of adipose tissue biology and both animal and human studies, which support a role of carotenoids and retinoids in the prevention of abdominal adiposity.Elsevier Science Inc20152015-04-1520152015-04-15review articlehttp://purl.org/coar/resource_type/c_dcae04bcinfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.13003/17317reponame:Docusalutinstname:Conselleria de Salut i Consum del Govern de les Illes BalearsInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:docusalut.com:20.500.13003/173172026-06-22T12:44:07Z
dc.title.none.fl_str_mv Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
title Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
spellingShingle Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
Luisa Bonet, M.
Humans
Obesity
Carotenoids
Adiposity
Animals
Adipocytes
Adipogenesis
Adipocitos
Obesidad
Humanos
Animales
Adipogénesis
Adiposidad
Carotenoides
Carotenoids
Apocarotenoids
Obesity
Adiposity
Energy metabolism
White adipose tissue browning
title_short Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
title_full Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
title_fullStr Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
title_full_unstemmed Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
title_sort Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
dc.creator.none.fl_str_mv Luisa Bonet, M.
Canas, Jose A.
Ribot, Joan
Palou, Andreu
author Luisa Bonet, M.
author_facet Luisa Bonet, M.
Canas, Jose A.
Ribot, Joan
Palou, Andreu
author_role author
author2 Canas, Jose A.
Ribot, Joan
Palou, Andreu
author2_role author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Humans
Obesity
Carotenoids
Adiposity
Animals
Adipocytes
Adipogenesis
Adipocitos
Obesidad
Humanos
Animales
Adipogénesis
Adiposidad
Carotenoides
Carotenoids
Apocarotenoids
Obesity
Adiposity
Energy metabolism
White adipose tissue browning
topic Humans
Obesity
Carotenoids
Adiposity
Animals
Adipocytes
Adipogenesis
Adipocitos
Obesidad
Humanos
Animales
Adipogénesis
Adiposidad
Carotenoides
Carotenoids
Apocarotenoids
Obesity
Adiposity
Energy metabolism
White adipose tissue browning
description A novel perspective of the function of carotenoids and carotenoid-derived products - including, but not restricted to, the retinoids - is emerging in recent years which connects these compounds to the control of adipocyte biology and body fat accumulation, with implications for the management of obesity, diabetes and cardiovascular disease. Cell and animal studies indicate that carotenoids and carotenoids derivatives can reduce adiposity and impact key aspects of adipose tissue biology including adipocyte differentiation, hypertrophy, capacity for fatty acid oxidation and thermogenesis (including browning of white adipose tissue) and secretory function. Epidemiological studies in humans associate higher dietary intakes and serum levels of carotenoids with decreased adiposity. Specifically designed human intervention studies, though still sparse, indicate a beneficial effect of carotenoid supplementation in the accrual of abdominal adiposity. The objective of this review is to summarize recent findings in this area, place them in physiological contexts, and provide likely regulatory schemes whenever possible. The focus will be on the effects of carotenoids as nutritional regulators of adipose tissue biology and both animal and human studies, which support a role of carotenoids and retinoids in the prevention of abdominal adiposity.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-04-15
2015
2015-04-15
dc.type.none.fl_str_mv review article
http://purl.org/coar/resource_type/c_dcae04bc
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.13003/17317
url https://hdl.handle.net/20.500.13003/17317
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier Science Inc
publisher.none.fl_str_mv Elsevier Science Inc
dc.source.none.fl_str_mv reponame:Docusalut
instname:Conselleria de Salut i Consum del Govern de les Illes Balears
instname_str Conselleria de Salut i Consum del Govern de les Illes Balears
reponame_str Docusalut
collection Docusalut
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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