Bacteria capture with magnetic nanoparticles modified with cationic carbosilane dendritic systems

Bacteria elimination from water sources is key to obtain drinkable water. Hence, the design of systems with ability to interact with bacteria and remove them from water is an attractive proposal. A diversity of polycationic macromolecules has shown bactericide properties, due to interactions with ba...

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Autores: Quintana Sánchez, Sara|||0000-0003-3184-716X, Barrios Gumiel, Andrea, Sánchez-Nieves Fernández, Javier|||0000-0003-0410-2285, Copa Patiño, José Luis|||0000-0002-2162-3907, Mata de la Mata, Francisco Javier de la|||0000-0003-0418-3935, Gómez Ramírez, Rafael|||0000-0001-6448-2414
Formato: artículo
Fecha de publicación:2022
País:España
Recursos:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:ebuah.uah.es:10017/59156
Acesso em linha:http://hdl.handle.net/10017/59156
https://dx.doi.org/10.1016/j.msec.2021.112622
Access Level:acceso abierto
Palavra-chave:Water purification
Magnetic nanoparticles
Bacteria
Dendrimer and dendron
Carbosilane
Química
Chemistry
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spelling Bacteria capture with magnetic nanoparticles modified with cationic carbosilane dendritic systemsQuintana Sánchez, Sara|||0000-0003-3184-716XBarrios Gumiel, AndreaSánchez-Nieves Fernández, Javier|||0000-0003-0410-2285Copa Patiño, José Luis|||0000-0002-2162-3907Mata de la Mata, Francisco Javier de la|||0000-0003-0418-3935Gómez Ramírez, Rafael|||0000-0001-6448-2414Water purificationMagnetic nanoparticlesBacteriaDendrimer and dendronCarbosilaneQuímicaChemistryBacteria elimination from water sources is key to obtain drinkable water. Hence, the design of systems with ability to interact with bacteria and remove them from water is an attractive proposal. A diversity of polycationic macromolecules has shown bactericide properties, due to interactions with bacteria membranes. In this work, we have grafted cationic carbosilane (CBS) dendrons and dendrimers on the surface of iron oxide magnetic nanoparticles (MNP), leading to NP (ca. 10 nm) that interact with bacteria by covering bacteria membrane. Application of an external magnetic field removes MNP from solution sweeping bacteria attached to them. The interaction of the MNP with Gram-positive S. aureus bacteria is more sensible to the size of dendritic system covering the MNP, whereas interaction with Gramnegative E. coli bacteria is more sensible to the density of cationic groups. Over 500 ppm of NPM, MNP covered with dendrons captured over 90% of both type of bacteria, whereas MNP covered with dendrimers were only able to capture S. aureus bacteria (over 90%) but not E. coli bacteria. Modified MNP were characterized by transmission electron microscopy (TEM), thermogravimetric analysis (TGA), Fourier-transform infrared spectroscopy (FTIR), Z potential and dynamic light scattering (DLS). Interaction with bacteria was analyzed by UV, TEM and scanning electron microscopy (SEM). Moreover, the possibility to recycle cationic dendronized MNP was explored.Ministerio de Economía, Industria y CompetitividadComunidad de MadridInstituto Ramón y Cajal de Investigación Sanitaria20222022-02-01journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10017/59156https://dx.doi.org/10.1016/j.msec.2021.112622reponame:e_Buah Biblioteca Digital Universidad de Alcaláinstname:Universidad de Alcalá (UAH)InglésengMinisterio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 Not available PID2020-112924RB-I00Comunidad de Madrid http://dx.doi.org/10.13039/100012818 Not available B2017%2FBMD-3703 NANODENDMEDComunidad de Madrid http://dx.doi.org/10.13039/100012818 Not available B2017%2FBMD-3733 IMMUNOTHERCANComunidad de Madrid http://dx.doi.org/10.13039/100012818 Not available EPU-INV%2F2020%2F014open accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ebuah.uah.es:10017/591562026-06-18T11:13:07Z
dc.title.none.fl_str_mv Bacteria capture with magnetic nanoparticles modified with cationic carbosilane dendritic systems
title Bacteria capture with magnetic nanoparticles modified with cationic carbosilane dendritic systems
spellingShingle Bacteria capture with magnetic nanoparticles modified with cationic carbosilane dendritic systems
Quintana Sánchez, Sara|||0000-0003-3184-716X
Water purification
Magnetic nanoparticles
Bacteria
Dendrimer and dendron
Carbosilane
Química
Chemistry
title_short Bacteria capture with magnetic nanoparticles modified with cationic carbosilane dendritic systems
title_full Bacteria capture with magnetic nanoparticles modified with cationic carbosilane dendritic systems
title_fullStr Bacteria capture with magnetic nanoparticles modified with cationic carbosilane dendritic systems
title_full_unstemmed Bacteria capture with magnetic nanoparticles modified with cationic carbosilane dendritic systems
title_sort Bacteria capture with magnetic nanoparticles modified with cationic carbosilane dendritic systems
dc.creator.none.fl_str_mv Quintana Sánchez, Sara|||0000-0003-3184-716X
Barrios Gumiel, Andrea
Sánchez-Nieves Fernández, Javier|||0000-0003-0410-2285
Copa Patiño, José Luis|||0000-0002-2162-3907
Mata de la Mata, Francisco Javier de la|||0000-0003-0418-3935
Gómez Ramírez, Rafael|||0000-0001-6448-2414
author Quintana Sánchez, Sara|||0000-0003-3184-716X
author_facet Quintana Sánchez, Sara|||0000-0003-3184-716X
Barrios Gumiel, Andrea
Sánchez-Nieves Fernández, Javier|||0000-0003-0410-2285
Copa Patiño, José Luis|||0000-0002-2162-3907
Mata de la Mata, Francisco Javier de la|||0000-0003-0418-3935
Gómez Ramírez, Rafael|||0000-0001-6448-2414
author_role author
author2 Barrios Gumiel, Andrea
Sánchez-Nieves Fernández, Javier|||0000-0003-0410-2285
Copa Patiño, José Luis|||0000-0002-2162-3907
Mata de la Mata, Francisco Javier de la|||0000-0003-0418-3935
Gómez Ramírez, Rafael|||0000-0001-6448-2414
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Water purification
Magnetic nanoparticles
Bacteria
Dendrimer and dendron
Carbosilane
Química
Chemistry
topic Water purification
Magnetic nanoparticles
Bacteria
Dendrimer and dendron
Carbosilane
Química
Chemistry
description Bacteria elimination from water sources is key to obtain drinkable water. Hence, the design of systems with ability to interact with bacteria and remove them from water is an attractive proposal. A diversity of polycationic macromolecules has shown bactericide properties, due to interactions with bacteria membranes. In this work, we have grafted cationic carbosilane (CBS) dendrons and dendrimers on the surface of iron oxide magnetic nanoparticles (MNP), leading to NP (ca. 10 nm) that interact with bacteria by covering bacteria membrane. Application of an external magnetic field removes MNP from solution sweeping bacteria attached to them. The interaction of the MNP with Gram-positive S. aureus bacteria is more sensible to the size of dendritic system covering the MNP, whereas interaction with Gramnegative E. coli bacteria is more sensible to the density of cationic groups. Over 500 ppm of NPM, MNP covered with dendrons captured over 90% of both type of bacteria, whereas MNP covered with dendrimers were only able to capture S. aureus bacteria (over 90%) but not E. coli bacteria. Modified MNP were characterized by transmission electron microscopy (TEM), thermogravimetric analysis (TGA), Fourier-transform infrared spectroscopy (FTIR), Z potential and dynamic light scattering (DLS). Interaction with bacteria was analyzed by UV, TEM and scanning electron microscopy (SEM). Moreover, the possibility to recycle cationic dendronized MNP was explored.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-02-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10017/59156
https://dx.doi.org/10.1016/j.msec.2021.112622
url http://hdl.handle.net/10017/59156
https://dx.doi.org/10.1016/j.msec.2021.112622
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Ministerio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 Not available PID2020-112924RB-I00
Comunidad de Madrid http://dx.doi.org/10.13039/100012818 Not available B2017%2FBMD-3703 NANODENDMED
Comunidad de Madrid http://dx.doi.org/10.13039/100012818 Not available B2017%2FBMD-3733 IMMUNOTHERCAN
Comunidad de Madrid http://dx.doi.org/10.13039/100012818 Not available EPU-INV%2F2020%2F014
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:e_Buah Biblioteca Digital Universidad de Alcalá
instname:Universidad de Alcalá (UAH)
instname_str Universidad de Alcalá (UAH)
reponame_str e_Buah Biblioteca Digital Universidad de Alcalá
collection e_Buah Biblioteca Digital Universidad de Alcalá
repository.name.fl_str_mv
repository.mail.fl_str_mv
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