Genomic characterization of the bivalve pathogen Vibrio europaeus

Bivalve hatcheries are essential for aquaculture, ensuring a stable seed supply, but face challenges, particularly mortalities caused by Vibrio species, known as vibriosis. These infections, primarily affecting larval stages, lead to significant economic losses. The pathogenicity of Vibrio depends o...

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Detalles Bibliográficos
Autor: Rodríguez Rodríguez, Sergio
Tipo de recurso: tesis doctoral
Fecha de publicación:2025
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/42463
Acceso en línea:https://hdl.handle.net/10347/42463
Access Level:acceso abierto
Palabra clave:Vibrio
bivalves
hatcheries
pangenome
virulence
251092 Acuicultura marina
241408 Procesos microbianos
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spelling Genomic characterization of the bivalve pathogen Vibrio europaeusRodríguez Rodríguez, SergioVibriobivalveshatcheriespangenomevirulence251092 Acuicultura marina241408 Procesos microbianosBivalve hatcheries are essential for aquaculture, ensuring a stable seed supply, but face challenges, particularly mortalities caused by Vibrio species, known as vibriosis. These infections, primarily affecting larval stages, lead to significant economic losses. The pathogenicity of Vibrio depends on virulence factors, host susceptibility, and environmental conditions, making prevention the best strategy. This Thesis focuses on Vibrio europaeus, a recently identified species associated with bivalve mortalities across various life stages and geographic regions. A genomic analysis was conducted on 39 strains from hatcheries worldwide. The V. europaeus pangenome, encompassing both core and accessory genes, revealed a species highly adaptable to its environment through DNA acquisition. Intraspecific variability analysis identified three phylogenetic branches and eight clusters, with Spanish strains showing lower diversity than French strains, indicating localized dispersal. In contrast, French strains were more diverse, and strains from Chile and the USA formed separate clusters, suggesting intercontinental transmission via human activities such as mollusc trade.Barja Pérez, Juan LuisDubert Pérez, JavierUniversidade de Santiago de Compostela. Escola de Doutoramento Internacional (EDIUS)20252025-01-0120252025-01-01doctoral thesishttp://purl.org/coar/resource_type/c_db06info:eu-repo/semantics/doctoralThesisapplication/pdfhttps://hdl.handle.net/10347/42463reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostelainstname:Universidad de Santiago de Compostela (USC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:minerva.usc.gal:10347/424632026-06-15T12:47:27Z
dc.title.none.fl_str_mv Genomic characterization of the bivalve pathogen Vibrio europaeus
title Genomic characterization of the bivalve pathogen Vibrio europaeus
spellingShingle Genomic characterization of the bivalve pathogen Vibrio europaeus
Rodríguez Rodríguez, Sergio
Vibrio
bivalves
hatcheries
pangenome
virulence
251092 Acuicultura marina
241408 Procesos microbianos
title_short Genomic characterization of the bivalve pathogen Vibrio europaeus
title_full Genomic characterization of the bivalve pathogen Vibrio europaeus
title_fullStr Genomic characterization of the bivalve pathogen Vibrio europaeus
title_full_unstemmed Genomic characterization of the bivalve pathogen Vibrio europaeus
title_sort Genomic characterization of the bivalve pathogen Vibrio europaeus
dc.creator.none.fl_str_mv Rodríguez Rodríguez, Sergio
author Rodríguez Rodríguez, Sergio
author_facet Rodríguez Rodríguez, Sergio
author_role author
dc.contributor.none.fl_str_mv Barja Pérez, Juan Luis
Dubert Pérez, Javier
Universidade de Santiago de Compostela. Escola de Doutoramento Internacional (EDIUS)
dc.subject.none.fl_str_mv Vibrio
bivalves
hatcheries
pangenome
virulence
251092 Acuicultura marina
241408 Procesos microbianos
topic Vibrio
bivalves
hatcheries
pangenome
virulence
251092 Acuicultura marina
241408 Procesos microbianos
description Bivalve hatcheries are essential for aquaculture, ensuring a stable seed supply, but face challenges, particularly mortalities caused by Vibrio species, known as vibriosis. These infections, primarily affecting larval stages, lead to significant economic losses. The pathogenicity of Vibrio depends on virulence factors, host susceptibility, and environmental conditions, making prevention the best strategy. This Thesis focuses on Vibrio europaeus, a recently identified species associated with bivalve mortalities across various life stages and geographic regions. A genomic analysis was conducted on 39 strains from hatcheries worldwide. The V. europaeus pangenome, encompassing both core and accessory genes, revealed a species highly adaptable to its environment through DNA acquisition. Intraspecific variability analysis identified three phylogenetic branches and eight clusters, with Spanish strains showing lower diversity than French strains, indicating localized dispersal. In contrast, French strains were more diverse, and strains from Chile and the USA formed separate clusters, suggesting intercontinental transmission via human activities such as mollusc trade.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025-01-01
2025
2025-01-01
dc.type.none.fl_str_mv doctoral thesis
http://purl.org/coar/resource_type/c_db06
dc.type.openaire.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
dc.identifier.none.fl_str_mv https://hdl.handle.net/10347/42463
url https://hdl.handle.net/10347/42463
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname:Universidad de Santiago de Compostela (USC)
instname_str Universidad de Santiago de Compostela (USC)
reponame_str Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
collection Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
repository.name.fl_str_mv
repository.mail.fl_str_mv
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