Green solvents in dispersive liquid-liquid microextraction for the determination of carbonyl compounds in coffee extracts
This work presents a greener approach for ultrasound-assisted (UA) dispersive liquid-liquid microextraction (DLLME) of carbonyl compounds from coffee samples, before GC–MS determination. This work aims to substitute the solvents used in the traditional DLLME procedures with greener alternatives and...
| Autores: | , , , , , |
|---|---|
| Tipo de documento: | artigo |
| Data de publicação: | 2025 |
| País: | España |
| Recursos: | Universidad de Santiago de Compostela (USC) |
| Repositório: | Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela |
| Idioma: | inglês |
| OAI Identifier: | oai:minerva.usc.gal:10347/43302 |
| Acesso em linha: | https://hdl.handle.net/10347/43302 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Carbonyl compounds Coffee Dispersive liquid-liquid microextraction GC-MS Low-density extractant solvent Sample preparation |
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Green solvents in dispersive liquid-liquid microextraction for the determination of carbonyl compounds in coffee extractsRangel Silva, AlexandraCustodio Mendoza, Jorge AntonioRodrigo Santos, JoãoAlmeida, Paulo Jorge SilvaRodrigues, José António MaiaCarro Díaz, Antonia MaríaCarbonyl compoundsCoffeeDispersive liquid-liquid microextractionGC-MSLow-density extractant solventSample preparationThis work presents a greener approach for ultrasound-assisted (UA) dispersive liquid-liquid microextraction (DLLME) of carbonyl compounds from coffee samples, before GC–MS determination. This work aims to substitute the solvents used in the traditional DLLME procedures with greener alternatives and to decrease the volume of solvents used. Low-density solvents, 1-octanol and isooctane, were evaluated as the extraction solvent. Optimization of critical experimental parameters was conducted in two stages: an asymmetrical screening design 2331 // 8, followed by a Doehlert experimental design. In the first experimental design 4 parameters were optimized: the volume of aqueous phase volume (1.5 mL), the concentration of the derivatization reagent solution pentafluorophenylhydrazine (1.12 g/L) and the volume and type of extraction solvent (60 µL of isooctane). In the second experimental design, 15 min of derivatization at 50 °C were selected as optimized conditions. The enrichment factor associated with the DLLME procedure enabled the efficient extraction of nine carbonyl compounds (acetaldehyde, acrolein, benzaldehyde, diacetyl, formaldehyde, furfural, glyoxal, malondialdehyde, and methylglyoxal) from coffee samples. The method demonstrated strong analytical performance, with figures of merit including r2 ≥ 0.9990, limits of detection between 289 and 436 µg/L, intraday, and interday precisions < 9.5 %. Recovery values for all nine carbonyl compounds ranged from 90.0 to 110.0 %. The greenness of the developed methodology was assessed using the AGREEprep tool, yielding a score of 0.59. Acetaldehyde, benzaldehyde and furfural were quantified in most coffee samples analyzed, with no significant differences observed in carbonyl compounds composition.ElsevierUniversidade de Santiago de Compostela. Instituto de Materiais (iMATUS)20252025-03-2920252025-03-29journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10347/43302reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostelainstname:Universidad de Santiago de Compostela (USC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2© 2025 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:minerva.usc.gal:10347/433022026-06-15T12:47:27Z |
| dc.title.none.fl_str_mv |
Green solvents in dispersive liquid-liquid microextraction for the determination of carbonyl compounds in coffee extracts |
| title |
Green solvents in dispersive liquid-liquid microextraction for the determination of carbonyl compounds in coffee extracts |
| spellingShingle |
Green solvents in dispersive liquid-liquid microextraction for the determination of carbonyl compounds in coffee extracts Rangel Silva, Alexandra Carbonyl compounds Coffee Dispersive liquid-liquid microextraction GC-MS Low-density extractant solvent Sample preparation |
| title_short |
Green solvents in dispersive liquid-liquid microextraction for the determination of carbonyl compounds in coffee extracts |
| title_full |
Green solvents in dispersive liquid-liquid microextraction for the determination of carbonyl compounds in coffee extracts |
| title_fullStr |
Green solvents in dispersive liquid-liquid microextraction for the determination of carbonyl compounds in coffee extracts |
| title_full_unstemmed |
Green solvents in dispersive liquid-liquid microextraction for the determination of carbonyl compounds in coffee extracts |
| title_sort |
Green solvents in dispersive liquid-liquid microextraction for the determination of carbonyl compounds in coffee extracts |
| dc.creator.none.fl_str_mv |
Rangel Silva, Alexandra Custodio Mendoza, Jorge Antonio Rodrigo Santos, João Almeida, Paulo Jorge Silva Rodrigues, José António Maia Carro Díaz, Antonia María |
| author |
Rangel Silva, Alexandra |
| author_facet |
Rangel Silva, Alexandra Custodio Mendoza, Jorge Antonio Rodrigo Santos, João Almeida, Paulo Jorge Silva Rodrigues, José António Maia Carro Díaz, Antonia María |
| author_role |
author |
| author2 |
Custodio Mendoza, Jorge Antonio Rodrigo Santos, João Almeida, Paulo Jorge Silva Rodrigues, José António Maia Carro Díaz, Antonia María |
| author2_role |
author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade de Santiago de Compostela. Instituto de Materiais (iMATUS) |
| dc.subject.none.fl_str_mv |
Carbonyl compounds Coffee Dispersive liquid-liquid microextraction GC-MS Low-density extractant solvent Sample preparation |
| topic |
Carbonyl compounds Coffee Dispersive liquid-liquid microextraction GC-MS Low-density extractant solvent Sample preparation |
| description |
This work presents a greener approach for ultrasound-assisted (UA) dispersive liquid-liquid microextraction (DLLME) of carbonyl compounds from coffee samples, before GC–MS determination. This work aims to substitute the solvents used in the traditional DLLME procedures with greener alternatives and to decrease the volume of solvents used. Low-density solvents, 1-octanol and isooctane, were evaluated as the extraction solvent. Optimization of critical experimental parameters was conducted in two stages: an asymmetrical screening design 2331 // 8, followed by a Doehlert experimental design. In the first experimental design 4 parameters were optimized: the volume of aqueous phase volume (1.5 mL), the concentration of the derivatization reagent solution pentafluorophenylhydrazine (1.12 g/L) and the volume and type of extraction solvent (60 µL of isooctane). In the second experimental design, 15 min of derivatization at 50 °C were selected as optimized conditions. The enrichment factor associated with the DLLME procedure enabled the efficient extraction of nine carbonyl compounds (acetaldehyde, acrolein, benzaldehyde, diacetyl, formaldehyde, furfural, glyoxal, malondialdehyde, and methylglyoxal) from coffee samples. The method demonstrated strong analytical performance, with figures of merit including r2 ≥ 0.9990, limits of detection between 289 and 436 µg/L, intraday, and interday precisions < 9.5 %. Recovery values for all nine carbonyl compounds ranged from 90.0 to 110.0 %. The greenness of the developed methodology was assessed using the AGREEprep tool, yielding a score of 0.59. Acetaldehyde, benzaldehyde and furfural were quantified in most coffee samples analyzed, with no significant differences observed in carbonyl compounds composition. |
| publishDate |
2025 |
| dc.date.none.fl_str_mv |
2025 2025-03-29 2025 2025-03-29 |
| dc.type.none.fl_str_mv |
journal article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/10347/43302 |
| url |
https://hdl.handle.net/10347/43302 |
| dc.language.none.fl_str_mv |
Inglés eng |
| language_invalid_str_mv |
Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 http://creativecommons.org/licenses/by/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 http://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Elsevier |
| publisher.none.fl_str_mv |
Elsevier |
| dc.source.none.fl_str_mv |
reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela instname:Universidad de Santiago de Compostela (USC) |
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Universidad de Santiago de Compostela (USC) |
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Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela |
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Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela |
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1869418327829381120 |
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15,811543 |